Rationale: cluster all secreted proteins based on their structures
secreted<-read.delim2( "../analysis_and_temp_files/01_predicting_effectors/all_secreted_list.txt", sep = "\t",header = F)
signal<-read.delim2("../analysis_and_temp_files/01_predicting_effectors/GTX0501_signalp_prediction_results.txt",skip=1) %>% filter(Prediction!="OTHER") %>%
mutate(TranscriptID = X..ID,
last_position_in_SP = as.numeric(gsub("CS pos: ([0-9]+)-.*$", "\\1", CS.Position))) %>%
select(TranscriptID,last_position_in_SP,CS.Position) %>%
filter(TranscriptID %in% secreted$V1)
library(Rpdb)
## Loading required package: rgl
## This build of rgl does not include OpenGL functions. Use
## rglwidget() to display results, e.g. via options(rgl.printRglwidget = TRUE).
##
## Attaching package: 'Rpdb'
## The following objects are masked from 'package:base':
##
## norm, replicate, unsplit
clip_SP <- function(input_file,output_file,residue){
pdb<-read.pdb(input_file)
pdb_subset<-subset(pdb,pdb$atoms$resid>residue)
write.pdb(pdb_subset,output_file)
rm(pdb,pdb_subset)}
df<-data.frame("input_file" = list.files("../analysis_and_temp_files/03_fold_secretome/colab_fold_best_model", pattern=".pdb",full.names = T)) %>%
mutate(TranscriptID = gsub("../analysis_and_temp_files/03_fold_secretome/colab_fold_best_model/(.*)_unrelaxed.*$", "\\1", input_file)) %>%
mutate(output_file = paste0("../analysis_and_temp_files/05_cluster_structures/pdb_signal_removed/",TranscriptID,"_clipped.pdb")) %>% left_join(signal)
mapply(clip_SP, df$input_file,df$output_file,df$last_position_in_SP)
analysis_and_temp_files/05_cluster_structures/pdb_signal_removed/ added an empty file identifiers.txt and an empty folder called structs
mv "${JOBNAME}/ADD HERE THE FOLDER NAME/"*.pdb "${JOBNAME}/ADD HERE THE FOLDER NAME"*.cif "${JOBNAME}/structs"foldtree_struct_tree.PP.nwk.rooted.finalanalysis_and_temp_files/05_cluster_structures/pdb_signal_removed_da39a.result.zipFoldtree produces three trees:
The trees seem very different
Anecdotally comparing the trees. Took one protein model: FUN_009178-T1
Took another example: FUN_005200-T1
In these examples, lddt works best
Results: the tree seems random. The proteins with identical or nearly identical sequences are grouped together, as expected. But beyond that, clades make no sense
After SP removal, some models still had disordered regions in the N-terminus
With Adam, we did his filtering, the files for this process is in analysis_and_temp_files/05_cluster_structures/pdb_signal_removed_filtering_Adam
Used Adam’s script byeSP.py (analysis_and_temp_files/05_cluster_structures/pdb_signal_removed_filtering_Adam/analysis_and_temp_files/05_cluster_structures/pdb_signal_removed_filtering_Adam/PDB_edit/byeSP.py) to clip all residues with pLDDT <=55 from the N-terminus. This should make sure that all parts of the disordered region are gone
analysis_and_temp_files/05_cluster_structures/pdb_signal_removed_filtering_Adam/PDB_edit/No_SP_Xep)
analysis_and_temp_files/05_cluster_structures/pdb_signal_removed_filtering_Adam/PDB_edit/No_SP_Xep_editRemoving low-confidence models:
analysis_and_temp_files/05_cluster_structures/pdb_signal_removed_filtering_Adam/pTM_sort/pTM_sort.py)
analysis_and_temp_files/05_cluster_structures/pdb_signal_removed_filtering_Adam/pTM_sortabove_50 and below_50Copied the final folder (above_50) to analysis_and_temp_files/05_cluster_structures/pdb_SP_removed_filtered. Added the empty structs/ and identifier.txt, and ziped them
Results: after filtering, had 393 proteins left
Analyzed these files with Foldtree, and got an error close to the end of the pipeline.
*_struct_tree.nwk. These files are not final (the final should be called *_struct_tree.PP.nwk.rooted.final). However, when I compared foldtree_struct_tree.nwk and foldtree_struct_tree.PP.nwk.rooted.final from the previous successful run, they were identical except for the rooting point. From this, I conclude that I can use the *_struct_tree.nwk files*_struct_tree.nwk were produced. To ensure that all three are produced, added one argument to the snakemake command --until quicktreeComparing the trees to each other and also to the previous run with the infiltered set of trees
The same anecdotal example: FUN_009178-T1
The same anecdotal example: FUN_005200-T1
Foldtree tree (pTM = global alignment) consistantly fails. Will use lDDT tree instead
On the large scale, all three trees are completely incongruent
library(ape)
library(treeio)
lddt<-treeio::read.newick("../analysis_and_temp_files/05_cluster_structures/pdb_SP_removed_filtered_da39a/lddt_struct_tree.nwk")
fold<-treeio::read.newick("../analysis_and_temp_files/05_cluster_structures/pdb_SP_removed_filtered_da39a/foldtree_struct_tree.nwk")
aln<-treeio::read.newick("../analysis_and_temp_files/05_cluster_structures/pdb_SP_removed_filtered_da39a/alntmscore_struct_tree.nwk")
assoc<-data.frame(fold$tip.label ,fold$tip.label)
cophyloplot(lddt,aln,assoc,space=400)
analysis_and_temp_files/05_cluster_structures/pdb_SP_removed_filtered_da39a/lddt_struct_tree_annotated.svganalysis_and_temp_files/05_cluster_structures/pdb_signal_removed/ folder, see above)library(jsonlite)
get_ptm<-function(jsonfile){
ptm<-fromJSON(jsonfile)$ptm
return(ptm)
}
df2<-data.frame("input_file" = list.files("../analysis_and_temp_files/03_fold_secretome/colab_fold_best_model", pattern=".json",full.names = T)) %>%
mutate(TranscriptID = gsub("../analysis_and_temp_files/03_fold_secretome/colab_fold_best_model/(.*)_scores.*$", "\\1", input_file))
df2$ptm<-mapply(get_ptm, df2$input_file)
get_avg_lddt<-function(input_file){
pdb<-read.pdb(input_file)
avg_lddt<-mean(pdb$atoms$temp)
return(avg_lddt)
}
df$avg_lddt<-mapply(get_avg_lddt, df$input_file)
pdb_stats<-df2 %>% select(-input_file) %>% left_join(df) %>% select(TranscriptID,ptm,avg_lddt,input_file,last_position_in_SP)
write.table(pdb_stats,"../analysis_and_temp_files/05_cluster_structures/pdb_stats.txt",col.names = T,row.names = F,quote = F,sep="\t")
clip_lddt <- function(input_file,output_file,threshold){
pdb<-read.pdb(input_file)
pdb_subset<-subset(pdb,pdb$atoms$temp>threshold)
write.pdb(pdb_subset,output_file)
rm(pdb,pdb_subset)}
pdb_stats<-read.delim2("../analysis_and_temp_files/05_cluster_structures/pdb_stats.txt")
df3<-data.frame("input_file" = list.files("../analysis_and_temp_files/05_cluster_structures/pdb_signal_removed/", pattern=".pdb",full.names = T)) %>%
mutate(TranscriptID = gsub("../analysis_and_temp_files/05_cluster_structures/pdb_signal_removed//(.*)_clipped.*$", "\\1", input_file)) %>%
mutate(output_file = paste0("../analysis_and_temp_files/05_cluster_structures/pdb_SP_removed_clipped_filtered/",TranscriptID,".pdb")) %>%
filter(TranscriptID %in% pdb_stats$TranscriptID[pdb_stats$ptm>=0.5])
mapply(clip_lddt, df3$input_file,df3$output_file,55)
/analysis_and_temp_files/05_cluster_structures/pdb_SP_removed_clipped_filtered_da39a_0/analysis_and_temp_files/05_cluster_structures/pdb_SP_removed_clipped_filtered_da39a_0/lddt_struct_tree_annotated.*
analysis_and_temp_files/05_cluster_structures/clusterin_lddt_clipped_filtered.txtclusters_df<-read.delim2("../analysis_and_temp_files/05_cluster_structures/clusterin_lddt_clipped_filtered.txt") %>% filter(cluster_id!="")
cluster_info<-clusters_df %>% group_by(cluster_id) %>% summarize(n_proteins=n()) %>%
left_join(clusters_df %>% select(-tip) %>% distinct())
cluster_info %>% group_by(n_proteins) %>%summarize(n=n())
## # A tibble: 12 × 2
## n_proteins n
## <int> <int>
## 1 1 1
## 2 2 42
## 3 3 12
## 4 4 8
## 5 5 7
## 6 6 1
## 7 7 2
## 8 8 7
## 9 9 1
## 10 11 1
## 11 12 1
## 12 15 1
ggplot(cluster_info)+
geom_histogram(aes(x=n_proteins))
library(phytools)
lddt<-treeio::read.newick("../analysis_and_temp_files/05_cluster_structures/pdb_SP_removed_clipped_filtered_da39a_0/lddt_struct_tree.nwk")
fold<-treeio::read.newick("../analysis_and_temp_files/05_cluster_structures/pdb_SP_removed_clipped_filtered_da39a_0/foldtree_struct_tree.nwk")
aln<-treeio::read.newick("../analysis_and_temp_files/05_cluster_structures/pdb_SP_removed_clipped_filtered_da39a_0/alntmscore_struct_tree.nwk")
lddt_rooted<-midpoint.root(lddt)
fold_rooted<-midpoint.root(fold)
aln_rooted<-midpoint.root(aln)
clade<-c("FUN_010209-T1","FUN_007256-T1","FUN_005784-T1")
data.frame(rbind(c("lddt","foldtree","aln"),sapply(c(lddt_rooted,fold_rooted,aln_rooted),is.monophyletic,tips=clade)))
## X1 X2 X3
## 1 lddt foldtree aln
## 2 TRUE FALSE TRUE
clusters_df<-read.delim2("../analysis_and_temp_files/05_cluster_structures/clusterin_lddt_clipped_filtered.txt") %>% filter(cluster_id!="")
cluster_info<-clusters_df %>% group_by(cluster_id) %>% summarize(n_proteins=n()) %>%
left_join(clusters_df %>% select(-tip) %>% distinct())
test_cluster<-function(cl){
tip_list<-clusters_df$tip[clusters_df$cluster_id==cl]
l<-is.monophyletic(lddt_rooted,tip_list)
f<-is.monophyletic(fold_rooted,tip_list)
a<-is.monophyletic(aln_rooted,tip_list)
df<-data.frame("cluster_id"=cl,"lDDT"=l,"pTM"=f,"Sequence"=a)
return(df)
}
l<-lapply(cluster_info$cluster_id,test_cluster)
cluster_info2<-cluster_info %>% left_join(do.call(rbind,l))
cluster_info2 %>%
kable(format = "html", col.names = colnames(cluster_info2)) %>%
kable_styling() %>%
kableExtra::scroll_box(width = "100%", height = "300px")
| cluster_id | n_proteins | descrition | interest | lDDT | pTM | Sequence |
|---|---|---|---|---|---|---|
| cl01 | 2 | Amidase | N | TRUE | TRUE | TRUE |
| cl02 | 3 | Tyrosinase | N | TRUE | FALSE | FALSE |
| cl03 | 2 | No annotation | N | TRUE | FALSE | FALSE |
| cl04 | 8 | No annotation | Y | TRUE | FALSE | FALSE |
| cl05 | 4 | Lipase | N | TRUE | FALSE | FALSE |
| cl06 | 4 | Carboxylesterase | N | TRUE | FALSE | FALSE |
| cl07 | 4 | Esterase | N | TRUE | FALSE | TRUE |
| cl08 | 2 | Annotations do not match | N | TRUE | FALSE | FALSE |
| cl09 | 5 | Peptidase S10P | N | TRUE | FALSE | FALSE |
| cl10 | 2 | Pyrethroid Hydrolase and Hydroxynitrile Lyase | N | TRUE | FALSE | FALSE |
| cl11 | 3 | Lipase | N | TRUE | FALSE | TRUE |
| cl12 | 2 | Esterase | N | TRUE | TRUE | TRUE |
| cl13 | 3 | No annotation | N | TRUE | FALSE | FALSE |
| cl14 | 2 | No annotation | N | TRUE | FALSE | FALSE |
| cl15 | 8 | No annotation | N | TRUE | FALSE | FALSE |
| cl16 | 2 | Ribonuclease/ribotoxin | Y | TRUE | FALSE | FALSE |
| cl17 | 2 | Peptidase S53 | N | TRUE | FALSE | TRUE |
| cl18 | 6 | Match to effector from Zymoseptoria | Y | TRUE | FALSE | FALSE |
| cl19 | 4 | No annotation | Y | TRUE | FALSE | FALSE |
| cl20 | 7 | No annotation | Y | TRUE | FALSE | FALSE |
| cl21 | 5 | Killer toxin | Y | TRUE | FALSE | FALSE |
| cl22 | 2 | No annotation | Y | TRUE | FALSE | FALSE |
| cl23 | 3 | No annotation | Y | TRUE | FALSE | FALSE |
| cl24 | 9 | Match to effector from Zymoseptoria | Y | FALSE | FALSE | FALSE |
| cl24a | 11 | Match to effector from Zymoseptoria | Y | TRUE | FALSE | FALSE |
| cl25 | 2 | Beta lactamase | N | TRUE | FALSE | FALSE |
| cl26 | 2 | DUF3455 | N | TRUE | FALSE | FALSE |
| cl27 | 2 | Cetoacetate decarboxylase | N | TRUE | FALSE | TRUE |
| cl28 | 2 | Mettalopeptidase | N | TRUE | FALSE | FALSE |
| cl29 | 4 | Extracellular membrane protein | N | TRUE | FALSE | FALSE |
| cl30 | 3 | No annotation | N | TRUE | FALSE | FALSE |
| cl31 | 4 | No annotation | N | TRUE | FALSE | FALSE |
| cl32 | 12 | Mettalopeptidase | N | TRUE | FALSE | FALSE |
| cl33 | 2 | Vacuolar protein sorting-associated protein 62 | N | TRUE | FALSE | TRUE |
| cl34 | 4 | SnoaL | N | TRUE | FALSE | FALSE |
| cl35 | 2 | Annotations do not match | N | TRUE | FALSE | FALSE |
| cl36 | 2 | SUN family | N | TRUE | FALSE | FALSE |
| cl37 | 2 | thaumatin-like | Y | TRUE | FALSE | FALSE |
| cl38 | 4 | thaumatin-like | Y | TRUE | FALSE | FALSE |
| cl39 | 2 | PIR domain | N | TRUE | FALSE | FALSE |
| cl40 | 2 | No annotation | N | TRUE | FALSE | TRUE |
| cl41 | 3 | Ricin B-like lectin | N | TRUE | FALSE | TRUE |
| cl42 | 1 | Match to Trichoderma effector | Y | TRUE | TRUE | TRUE |
| cl43 | 2 | GH43 | N | TRUE | FALSE | TRUE |
| cl44 | 2 | Six-bladed beta-propeller, TolB-like | N | TRUE | FALSE | FALSE |
| cl45 | 2 | Arylsulfotransferase-like | N | TRUE | FALSE | TRUE |
| cl46 | 3 | Annotations do not match | N | TRUE | FALSE | FALSE |
| cl47 | 2 | Germins cupins | N | TRUE | FALSE | FALSE |
| cl48 | 3 | No annotation | N | TRUE | FALSE | TRUE |
| cl49 | 8 | GH16 | N | TRUE | FALSE | FALSE |
| cl50 | 2 | GH12 | N | TRUE | FALSE | TRUE |
| cl51 | 8 | Galactose-binding domain | N | TRUE | FALSE | FALSE |
| cl52 | 5 | No annotation | N | TRUE | FALSE | FALSE |
| cl53 | 5 | Galactose-binding domain Coagulation factor. different otherwise | N | TRUE | FALSE | FALSE |
| cl54 | 2 | Chloroperoxidase | N | TRUE | FALSE | FALSE |
| cl55 | 3 | FAD linked oxidase | N | TRUE | FALSE | TRUE |
| cl56 | 15 | flavoprotein EncM | N | TRUE | FALSE | FALSE |
| cl57 | 2 | SGNH hydrolase domain | N | TRUE | FALSE | FALSE |
| cl58 | 3 | GDSL lipase/esterase | N | TRUE | FALSE | FALSE |
| cl59 | 5 | GH128 | N | TRUE | FALSE | FALSE |
| cl60 | 2 | Spherulation | N | TRUE | FALSE | FALSE |
| cl61 | 2 | GH71 | N | TRUE | FALSE | FALSE |
| cl62 | 2 | GH20 | N | TRUE | TRUE | FALSE |
| cl63 | 3 | GH5 | N | TRUE | FALSE | FALSE |
| cl64 | 2 | GH5 | N | TRUE | FALSE | FALSE |
| cl65 | 8 | GH72 | N | TRUE | FALSE | FALSE |
| cl66 | 2 | No annotation | N | TRUE | FALSE | FALSE |
| cl67 | 8 | Kremen-like | N | TRUE | FALSE | FALSE |
| cl68 | 2 | Ferritin-like | N | TRUE | FALSE | TRUE |
| cl69 | 2 | Purple acid phosphatase-like | N | TRUE | TRUE | TRUE |
| cl70 | 2 | AA9 | N | TRUE | FALSE | FALSE |
| cl71 | 5 | Chitin-binding. matching by small part | N | TRUE | FALSE | FALSE |
| cl72 | 2 | Phosphatidylethanolamine-binding protein | N | TRUE | FALSE | FALSE |
| cl73 | 2 | No annotation | N | TRUE | FALSE | FALSE |
| cl74 | 2 | No annotation | N | TRUE | FALSE | TRUE |
| cl75 | 2 | Endonuclease/exonuclease/phosphatase | N | TRUE | TRUE | TRUE |
| cl76 | 2 | Aminopeptidase M28 | N | TRUE | TRUE | TRUE |
| cl77 | 2 | Patulin synthase | N | TRUE | FALSE | FALSE |
| cl78 | 7 | Cholin/aryl-alcohol oxidase | N | TRUE | FALSE | FALSE |
| cl79 | 2 | No annotation | N | TRUE | FALSE | FALSE |
| cl80 | 2 | Gamma-crystallin-like | N | TRUE | FALSE | FALSE |
| cl81 | 8 | Aspartic peptidase | N | TRUE | FALSE | FALSE |
| cl82 | 3 | No annotation | N | TRUE | FALSE | TRUE |
| cl83 | 5 | Papain inbitor | N | TRUE | FALSE | FALSE |
library(ggtree)
library(RColorBrewer)
col_1<-cluster_info %>% mutate(selected = ifelse(
cluster_id %in% c("cl18","cl19","cl20","cl21","cl22","cl23","cl24","cl24a"),cluster_id,"other")) %>% select(cluster_id,selected)
col_f1<-data.frame("tip"=fold$tip.label) %>% left_join(clusters_df) %>%
left_join(col_1)
ggtree(fold,ladderize = TRUE,right = T) %<+% col_f1 +
geom_tiplab(pch=16,size=3,aes(col=selected))+
scale_color_manual(values=c("other"="black","cl18"=brewer.pal(n = 8, name = "Dark2")[1],
"cl19"=brewer.pal(n = 8, name = "Dark2")[2],
"cl20"=brewer.pal(n = 8, name = "Dark2")[3],
"cl21"=brewer.pal(n = 8, name = "Dark2")[4],
"cl22"=brewer.pal(n = 8, name = "Dark2")[5],
"cl23"=brewer.pal(n = 8, name = "Dark2")[6],
"cl24"=brewer.pal(n = 8, name = "Dark2")[7],
"cl24a"="red"))+
xlim(0, 1.2)
col_a1<-data.frame("tip"=aln$tip.label) %>% left_join(clusters_df) %>%
left_join(col_1)
ggtree(aln,ladderize = TRUE,right = T) %<+% col_a1 +
geom_tiplab(pch=16,size=3,aes(col=selected))+
scale_color_manual(values=c("other"="black", #NA="black",
"cl18"=brewer.pal(n = 8, name = "Dark2")[1],
"cl19"=brewer.pal(n = 8, name = "Dark2")[2],
"cl20"=brewer.pal(n = 8, name = "Dark2")[3],
"cl21"=brewer.pal(n = 8, name = "Dark2")[4],
"cl22"=brewer.pal(n = 8, name = "Dark2")[5],
"cl23"=brewer.pal(n = 8, name = "Dark2")[6],
"cl24"=brewer.pal(n = 8, name = "Dark2")[7],
"cl24a"="red"))+
xlim(0, 1.2)
col_l1<-data.frame("tip"=lddt$tip.label) %>% left_join(clusters_df) %>%
left_join(col_1)
ggtree(lddt,ladderize = TRUE,right = T) %<+% col_l1 +
geom_tiplab(pch=16,size=3,aes(col=selected))+
scale_color_manual(values=c("other"="black",
"cl18"=brewer.pal(n = 8, name = "Dark2")[1],
"cl19"=brewer.pal(n = 8, name = "Dark2")[2],
"cl20"=brewer.pal(n = 8, name = "Dark2")[3],
"cl21"=brewer.pal(n = 8, name = "Dark2")[4],
"cl22"=brewer.pal(n = 8, name = "Dark2")[5],
"cl23"=brewer.pal(n = 8, name = "Dark2")[6],
"cl24"=brewer.pal(n = 8, name = "Dark2")[7],
"cl24a"="red"))+
xlim(0, 1.2)
library(Biostrings)
## Warning: package 'S4Vectors' was built under R version 4.1.3
all_fa<-readAAStringSet("../analysis_and_temp_files/01_predicting_effectors/all_secreted.fa")
subset_fa<-all_fa[df3$TranscriptID]
writeXStringSet(subset_fa,"../analysis_and_temp_files/05_cluster_structures/filtered.fa")
sbatch --mem=10G -c 20 --partition=tsl-short --wrap="source package /tgac/software/testing/bin/mafft-7.271; mafft --maxiterate 1000 --genafpair --thread 20 analysis_and_temp_files/05_cluster_structures/filtered.fa > analysis_and_temp_files/05_cluster_structures/filtered_aligned.fa"
sbatch --mem=10G -c 20 --partition=tsl-short --wrap="source package /tsl/software/testing/bin/trimal-1.2; trimal -in analysis_and_temp_files/05_cluster_structures/filtered_aligned.fa -out analysis_and_temp_files/05_cluster_structures/filtered_aligned.phyl -gt 0.01 -phylip"
sbatch --mem=20G -c 25 --partition=tsl-long --wrap="source package /tgac/software/testing/bin/iqtree-2.2.2.2; iqtree2 -s analysis_and_temp_files/05_cluster_structures/filtered_aligned.phyl -B 1000 -T 25 --threads-max 25"
iq<-treeio::read.newick("../analysis_and_temp_files/05_cluster_structures/filtered_aligned.phyl.contree")
iq_rooted<-midpoint.root(iq)
#rename tips in iqtree to make consistent
rename<-data.frame("new"=lddt_rooted$tip.label) %>% mutate(iq_old=sub("-.*", "", new))
rename<-data.frame("iq_old"=iq_rooted$tip.label) %>% left_join(rename)
## Joining with `by = join_by(iq_old)`
iq_rooted$tip.label<-rename$new
#test clusters
test_cluster2<-function(cl){
tip_list<-clusters_df$tip[clusters_df$cluster_id==cl]
i<-is.monophyletic(iq_rooted,tip_list)
l<-is.monophyletic(lddt_rooted,tip_list)
f<-is.monophyletic(fold_rooted,tip_list)
a<-is.monophyletic(aln_rooted,tip_list)
df<-data.frame("cluster_id"=cl,"IQTREE_sequence"=i,"FOldtree_sequence"=a,"lDDT"=l,"pTM"=f)
return(df)
}
l<-lapply(cluster_info$cluster_id,test_cluster2)
cluster_info3<-cluster_info %>% left_join(do.call(rbind,l))
## Joining with `by = join_by(cluster_id)`
cluster_info3 %>%
kable(format = "html", col.names = colnames(cluster_info3)) %>%
kable_styling() %>%
kableExtra::scroll_box(width = "100%", height = "300px")
| cluster_id | n_proteins | descrition | interest | IQTREE_sequence | FOldtree_sequence | lDDT | pTM |
|---|---|---|---|---|---|---|---|
| cl01 | 2 | Amidase | N | TRUE | TRUE | TRUE | TRUE |
| cl02 | 3 | Tyrosinase | N | FALSE | FALSE | TRUE | FALSE |
| cl03 | 2 | No annotation | N | FALSE | FALSE | TRUE | FALSE |
| cl04 | 8 | No annotation | Y | FALSE | FALSE | TRUE | FALSE |
| cl05 | 4 | Lipase | N | FALSE | FALSE | TRUE | FALSE |
| cl06 | 4 | Carboxylesterase | N | FALSE | FALSE | TRUE | FALSE |
| cl07 | 4 | Esterase | N | TRUE | TRUE | TRUE | FALSE |
| cl08 | 2 | Annotations do not match | N | FALSE | FALSE | TRUE | FALSE |
| cl09 | 5 | Peptidase S10P | N | FALSE | FALSE | TRUE | FALSE |
| cl10 | 2 | Pyrethroid Hydrolase and Hydroxynitrile Lyase | N | TRUE | FALSE | TRUE | FALSE |
| cl11 | 3 | Lipase | N | FALSE | TRUE | TRUE | FALSE |
| cl12 | 2 | Esterase | N | TRUE | TRUE | TRUE | TRUE |
| cl13 | 3 | No annotation | N | FALSE | FALSE | TRUE | FALSE |
| cl14 | 2 | No annotation | N | FALSE | FALSE | TRUE | FALSE |
| cl15 | 8 | No annotation | N | FALSE | FALSE | TRUE | FALSE |
| cl16 | 2 | Ribonuclease/ribotoxin | Y | FALSE | FALSE | TRUE | FALSE |
| cl17 | 2 | Peptidase S53 | N | TRUE | TRUE | TRUE | FALSE |
| cl18 | 6 | Match to effector from Zymoseptoria | Y | FALSE | FALSE | TRUE | FALSE |
| cl19 | 4 | No annotation | Y | FALSE | FALSE | TRUE | FALSE |
| cl20 | 7 | No annotation | Y | FALSE | FALSE | TRUE | FALSE |
| cl21 | 5 | Killer toxin | Y | FALSE | FALSE | TRUE | FALSE |
| cl22 | 2 | No annotation | Y | FALSE | FALSE | TRUE | FALSE |
| cl23 | 3 | No annotation | Y | FALSE | FALSE | TRUE | FALSE |
| cl24 | 9 | Match to effector from Zymoseptoria | Y | FALSE | FALSE | FALSE | FALSE |
| cl24a | 11 | Match to effector from Zymoseptoria | Y | FALSE | FALSE | TRUE | FALSE |
| cl25 | 2 | Beta lactamase | N | FALSE | FALSE | TRUE | FALSE |
| cl26 | 2 | DUF3455 | N | FALSE | FALSE | TRUE | FALSE |
| cl27 | 2 | Cetoacetate decarboxylase | N | FALSE | TRUE | TRUE | FALSE |
| cl28 | 2 | Mettalopeptidase | N | FALSE | FALSE | TRUE | FALSE |
| cl29 | 4 | Extracellular membrane protein | N | TRUE | FALSE | TRUE | FALSE |
| cl30 | 3 | No annotation | N | FALSE | FALSE | TRUE | FALSE |
| cl31 | 4 | No annotation | N | FALSE | FALSE | TRUE | FALSE |
| cl32 | 12 | Mettalopeptidase | N | FALSE | FALSE | TRUE | FALSE |
| cl33 | 2 | Vacuolar protein sorting-associated protein 62 | N | TRUE | TRUE | TRUE | FALSE |
| cl34 | 4 | SnoaL | N | FALSE | FALSE | TRUE | FALSE |
| cl35 | 2 | Annotations do not match | N | FALSE | FALSE | TRUE | FALSE |
| cl36 | 2 | SUN family | N | FALSE | FALSE | TRUE | FALSE |
| cl37 | 2 | thaumatin-like | Y | TRUE | FALSE | TRUE | FALSE |
| cl38 | 4 | thaumatin-like | Y | FALSE | FALSE | TRUE | FALSE |
| cl39 | 2 | PIR domain | N | FALSE | FALSE | TRUE | FALSE |
| cl40 | 2 | No annotation | N | FALSE | TRUE | TRUE | FALSE |
| cl41 | 3 | Ricin B-like lectin | N | FALSE | TRUE | TRUE | FALSE |
| cl42 | 1 | Match to Trichoderma effector | Y | TRUE | TRUE | TRUE | TRUE |
| cl43 | 2 | GH43 | N | FALSE | TRUE | TRUE | FALSE |
| cl44 | 2 | Six-bladed beta-propeller, TolB-like | N | FALSE | FALSE | TRUE | FALSE |
| cl45 | 2 | Arylsulfotransferase-like | N | TRUE | TRUE | TRUE | FALSE |
| cl46 | 3 | Annotations do not match | N | FALSE | FALSE | TRUE | FALSE |
| cl47 | 2 | Germins cupins | N | FALSE | FALSE | TRUE | FALSE |
| cl48 | 3 | No annotation | N | TRUE | TRUE | TRUE | FALSE |
| cl49 | 8 | GH16 | N | FALSE | FALSE | TRUE | FALSE |
| cl50 | 2 | GH12 | N | FALSE | TRUE | TRUE | FALSE |
| cl51 | 8 | Galactose-binding domain | N | FALSE | FALSE | TRUE | FALSE |
| cl52 | 5 | No annotation | N | FALSE | FALSE | TRUE | FALSE |
| cl53 | 5 | Galactose-binding domain Coagulation factor. different otherwise | N | FALSE | FALSE | TRUE | FALSE |
| cl54 | 2 | Chloroperoxidase | N | FALSE | FALSE | TRUE | FALSE |
| cl55 | 3 | FAD linked oxidase | N | TRUE | TRUE | TRUE | FALSE |
| cl56 | 15 | flavoprotein EncM | N | FALSE | FALSE | TRUE | FALSE |
| cl57 | 2 | SGNH hydrolase domain | N | FALSE | FALSE | TRUE | FALSE |
| cl58 | 3 | GDSL lipase/esterase | N | TRUE | FALSE | TRUE | FALSE |
| cl59 | 5 | GH128 | N | FALSE | FALSE | TRUE | FALSE |
| cl60 | 2 | Spherulation | N | TRUE | FALSE | TRUE | FALSE |
| cl61 | 2 | GH71 | N | FALSE | FALSE | TRUE | FALSE |
| cl62 | 2 | GH20 | N | TRUE | FALSE | TRUE | TRUE |
| cl63 | 3 | GH5 | N | TRUE | FALSE | TRUE | FALSE |
| cl64 | 2 | GH5 | N | FALSE | FALSE | TRUE | FALSE |
| cl65 | 8 | GH72 | N | FALSE | FALSE | TRUE | FALSE |
| cl66 | 2 | No annotation | N | FALSE | FALSE | TRUE | FALSE |
| cl67 | 8 | Kremen-like | N | FALSE | FALSE | TRUE | FALSE |
| cl68 | 2 | Ferritin-like | N | FALSE | TRUE | TRUE | FALSE |
| cl69 | 2 | Purple acid phosphatase-like | N | TRUE | TRUE | TRUE | TRUE |
| cl70 | 2 | AA9 | N | FALSE | FALSE | TRUE | FALSE |
| cl71 | 5 | Chitin-binding. matching by small part | N | FALSE | FALSE | TRUE | FALSE |
| cl72 | 2 | Phosphatidylethanolamine-binding protein | N | FALSE | FALSE | TRUE | FALSE |
| cl73 | 2 | No annotation | N | FALSE | FALSE | TRUE | FALSE |
| cl74 | 2 | No annotation | N | TRUE | TRUE | TRUE | FALSE |
| cl75 | 2 | Endonuclease/exonuclease/phosphatase | N | TRUE | TRUE | TRUE | TRUE |
| cl76 | 2 | Aminopeptidase M28 | N | TRUE | TRUE | TRUE | TRUE |
| cl77 | 2 | Patulin synthase | N | TRUE | FALSE | TRUE | FALSE |
| cl78 | 7 | Cholin/aryl-alcohol oxidase | N | FALSE | FALSE | TRUE | FALSE |
| cl79 | 2 | No annotation | N | FALSE | FALSE | TRUE | FALSE |
| cl80 | 2 | Gamma-crystallin-like | N | FALSE | FALSE | TRUE | FALSE |
| cl81 | 8 | Aspartic peptidase | N | FALSE | FALSE | TRUE | FALSE |
| cl82 | 3 | No annotation | N | TRUE | TRUE | TRUE | FALSE |
| cl83 | 5 | Papain inbitor | N | FALSE | FALSE | TRUE | FALSE |
col_i1<-data.frame("tip"=iq_rooted$tip.label) %>% left_join(clusters_df) %>%
left_join(col_1)
ggtree(iq_rooted,ladderize = TRUE,right = T) %<+% col_i1 +
geom_tiplab(pch=16,size=3,aes(col=selected))+
scale_color_manual(values=c("other"="black",
"cl18"=brewer.pal(n = 8, name = "Dark2")[1],
"cl19"=brewer.pal(n = 8, name = "Dark2")[2],
"cl20"=brewer.pal(n = 8, name = "Dark2")[3],
"cl21"=brewer.pal(n = 8, name = "Dark2")[4],
"cl22"=brewer.pal(n = 8, name = "Dark2")[5],
"cl23"=brewer.pal(n = 8, name = "Dark2")[6],
"cl24"=brewer.pal(n = 8, name = "Dark2")[7],
"cl24a"="red"))+
xlim(0, 5)+geom_treescale()
analysis_and_temp_files/05_cluster_structures/clustering_results.txtann<-read.delim("../analysis_and_temp_files/04_characterize_secretome/secretome_annotations.txt")
clusters_df$TranscriptID <- str_replace(clusters_df$tip,"FUN","XANPAGTX0501")
pdb_stats$TranscriptID <- str_replace(pdb_stats$TranscriptID,"FUN","XANPAGTX0501")
size<-data.frame("size"=width(all_fa),"name"=names(all_fa))
size$TranscriptID <- str_replace(size$name,"FUN","XANPAGTX0501")
combined<-ann %>% left_join(clusters_df) %>% left_join(pdb_stats) %>% left_join(size) %>%
select(TranscriptID,cluster_id,descrition,DGE,ptm,pLDDT,size,InterPro,CAZyme_new,Protease_new,antimicrobial,pdb_best,pdb_second,af_best,af_second) %>%
mutate(cluster_id = case_when(is.na(cluster_id) & ptm>=0.5 ~ "not in cluster",
is.na(cluster_id) & ptm<0.5 ~ "pTM below threshold",
T ~ cluster_id)) %>% arrange(cluster_id)
colnames(combined)<-c("ProteinID","ClusterID","CLuster_Description","Gene_Expression",
"pTM_Score", "Average_pLDDT", "Size_aa", "InterPro", "CAZyme_new","Protease_new","Antimicrobial_activity_prediction","Best_match_PDB","Second_match_PDB","Best_match_AF","Second_match_AF")
write.table(combined,"../analysis_and_temp_files/05_cluster_structures/clustering_results.txt",col.names = T,row.names = F,quote = F,sep="\t")
combined %>%
kable(format = "html", col.names = colnames(combined)) %>%
kable_styling() %>%
kableExtra::scroll_box(width = "100%", height = "300px")
| ProteinID | ClusterID | CLuster_Description | Gene_Expression | pTM_Score | Average_pLDDT | Size_aa | InterPro | CAZyme_new | Protease_new | Antimicrobial_activity_prediction | Best_match_PDB | Second_match_PDB | Best_match_AF | Second_match_AF |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| XANPAGTX0501_001769-T1 | cl01 | Amidase | Non-DGE | 0.92 | 92.03780 | 644 | IPR023631 Amidase signature domain;IPR036928 Amidase signature (AS) superfamily | NA | NA | Non-antimicrobial | 1OBL; crystal structure of the S133A mutant of Malonamidase E2 complexed with malonate from Bradyrhizobium japonicum; 1.039e-22 | 1OCK; THE CRYSTAL STRUCTURE OF MALONAMIDASE E2 FROM BRADYRHIZOBIUM JAPONICUM; 7.681e-22 | A0A1V8UQ83; Amidase domain-containing protein; Rachicladosporium sp. CCFEE 5018; 1.283e-90 | A0A1F5LL44; Amidase domain-containing protein; Penicillium arizonense; 1.425e-75 |
| XANPAGTX0501_010624-T1 | cl01 | Amidase | Upregulated in lichen | 0.92 | 92.40121 | 652 | IPR023631 Amidase signature domain;IPR036928 Amidase signature (AS) superfamily | NA | NA | Antimicrobial | 2DC0; Crystal structure of amidase; 1.145e-21 | 1OBL; crystal structure of the S133A mutant of Malonamidase E2 complexed with malonate from Bradyrhizobium japonicum; 1.916e-21 | L7J9U7; Glutamyl-tRNA(Gln) amidotransferase; Pyricularia oryzae (strain P131) (Rice blast fungus) (Magnaporthe oryzae); 4.605e-77 | A0A4Y9XTD4; Amidase domain-containing protein; Rhodofomes roseus; 2.156e-76 |
| XANPAGTX0501_001150-T1 | cl02 | Tyrosinase | Non-DGE | 0.91 | 90.56552 | 598 | IPR002227 Tyrosinase copper-binding domain;IPR008922 Di-copper centre-containing domain superfamily;IPR041640 Tyosinase, C-terminal | NA | NA | Non-antimicrobial | 4OUA; Coexistent single-crystal structure of latent and active mushroom tyrosinase (abPPO4) mediated by a hexatungstotellurate(VI); 1.152e-36 | 5M6B; structure of recombinant mushroom tyrosinase (abPPO4); 8.655e-36 | A0A232M6A5; tyrosinase (EC 1.14.18.1); Elaphomyces granulatus; 4.536e-59 | U1HZ89; tyrosinase (EC 1.14.18.1); Endocarpon pusillum (strain Z07020 / HMAS-L-300199) (Lichen-forming fungus); 1.573e-56 |
| XANPAGTX0501_003876-T1 | cl02 | Tyrosinase | Non-DGE | 0.9 | 92.56312 | 381 | IPR002227 Tyrosinase copper-binding domain;IPR008922 Di-copper centre-containing domain superfamily | NA | NA | Non-antimicrobial | 5OR3; Crystal structure of Aspergillus oryzae catechol oxidase in met/deoxy-form; 9.865e-36 | 4J3Q; Crystal structure of truncated catechol oxidase from Aspergillus oryzae; 1.012e-33 | A0A1L7XJB2; Related to monophenol monooxygenase (Tyrosinase); Phialocephala subalpina; 3.877e-35 | A0A6A6W082; Tyrosinase; Pseudovirgaria hyperparasitica; 1.885e-34 |
| XANPAGTX0501_004818-T1 | cl02 | Tyrosinase | Non-DGE | 0.82 | 83.06497 | 294 | IPR002227 Tyrosinase copper-binding domain;IPR008922 Di-copper centre-containing domain superfamily | NA | NA | Antimicrobial | 5M6B; structure of recombinant mushroom tyrosinase (abPPO4); 1.623e-14 | 6JUD; Radiation damage in Aspergillus oryzae pro-tyrosinase oxygen-bound C92A/H103F mutant; 1.781e-13 | A0A5M8PXI5; tyrosinase (EC 1.14.18.1); Lasallia pustulata; 1.841e-22 | A0A1Y1ZT51; Common central domain of tyrosinase-domain-containing protein; Clohesyomyces aquaticus; 2.572e-22 |
| XANPAGTX0501_001123-T1 | cl03 | No annotation | Non-DGE | 0.51 | 68.40650 | 203 | NA | NA | NA | Non-antimicrobial | NA | NA | A0A0K8L317; deleted; ; 9.48e-14 | A0A5M9M9I3; 4Fe-4S ferredoxin-type domain-containing protein; Aspergillus tanneri; 2.749e-13 |
| XANPAGTX0501_003936-T1 | cl03 | No annotation | Non-DGE | 0.5 | 69.73432 | 192 | NA | NA | NA | Non-antimicrobial | NA | NA | A0A165K0S4; PCI domain-containing protein; Xylona heveae (strain CBS 132557 / TC161); 2.041e-09 | A0A1W5DB61; Uncharacterized protein; Lasallia pustulata; 5.797e-09 |
| XANPAGTX0501_000516-T1 | cl04 | No annotation | Non-DGE | 0.54 | 53.96782 | 298 | NA | NA | NA | Below pLDDT threshold | NA | NA | A0A177DZ91; Uncharacterized protein; Alternaria alternata (Alternaria rot fungus) (Torula alternata); 2.617e-08 | A0A4Q4QFQ8; deleted; ; 4.084e-08 |
| XANPAGTX0501_002012-T1 | cl04 | No annotation | Non-DGE | 0.62 | 60.28573 | 295 | NA | NA | NA | Below pLDDT threshold | NA | NA | A0A194X1P8; Uncharacterized protein; Mollisia scopiformis (Conifer needle endophyte fungus) (Phialocephala scopiformis); 8.6e-14 | A0A384JZK1; Uncharacterized protein; Botryotinia fuckeliana (strain B05.10) (Noble rot fungus) (Botrytis cinerea); 5.239e-12 |
| XANPAGTX0501_002315-T2 | cl04 | No annotation | Upregulated in lichen | 0.63 | 58.00690 | 316 | NA | NA | NA | Below pLDDT threshold | NA | NA | A0A1Y1YB21; Uncharacterized protein; Clohesyomyces aquaticus; 8.593e-08 | A0A4Q4SRX6; Uncharacterized protein; Alternaria arborescens; 1.329e-07 |
| XANPAGTX0501_003678-T1 | cl04 | No annotation | Non-DGE | 0.81 | 79.67219 | 274 | NA | NA | NA | Non-antimicrobial | NA | NA | A0A7C8MK18; Uncharacterized protein; Massariosphaeria phaeospora; 6.646e-11 | A0A194X1P8; Uncharacterized protein; Mollisia scopiformis (Conifer needle endophyte fungus) (Phialocephala scopiformis); 9.511e-11 |
| XANPAGTX0501_005039-T1 | cl04 | No annotation | Non-DGE | 0.69 | 65.00582 | 282 | NA | NA | NA | Non-antimicrobial | NA | NA | A0A1V8SC36; Uncharacterized protein; Rachicladosporium antarcticum; 6.292e-09 | A0A1V8VA03; Uncharacterized protein; Rachicladosporium sp. CCFEE 5018; 9.701e-09 |
| XANPAGTX0501_005768-T1 | cl04 | No annotation | Non-DGE | 0.65 | 62.55987 | 301 | NA | NA | NA | Below pLDDT threshold | NA | NA | A0A4Z1GB68; Uncharacterized protein; Botrytis hyacinthi; 5.298e-09 | A0A4Z1HMH8; Uncharacterized protein; Botryotinia convoluta; 1.316e-08 |
| XANPAGTX0501_009148-T1 | cl04 | No annotation | Non-DGE | 0.55 | 51.94609 | 289 | NA | NA | NA | Below pLDDT threshold | NA | NA | A0A0F7U4N9; Uncharacterized protein; Penicillium brasilianum; 2.078e-08 | A0A7J6IN97; Uncharacterized protein; Colletotrichum fructicola (strain Nara gc5) (Anthracnose fungus) (Colletotrichum gloeosporioides (strain Nara gc5)); 2.075e-06 |
| XANPAGTX0501_010247-T1 | cl04 | No annotation | Upregulated in lichen | 0.69 | 65.92789 | 331 | NA | NA | NA | Non-antimicrobial | NA | NA | A0A6A7BBL6; Uncharacterized protein; Plenodomus tracheiphilus IPT5; 2.921e-15 | E5A2A2; Uncharacterized protein; Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8) (Blackleg fungus) (Phoma lingam); 5.012e-13 |
| XANPAGTX0501_002910-T1 | cl05 | Lipase | Non-DGE | 0.76 | 74.32514 | 391 | IPR002921 Fungal lipase-like domain;IPR029058 Alpha/Beta hydrolase fold | NA | NA | Non-antimicrobial | 3O0D; Crystal structure of Lip2 lipase from Yarrowia lipolytica at 1.7 A resolution; 4.744e-24 | 3O0D; Crystal structure of Lip2 lipase from Yarrowia lipolytica at 1.7 A resolution; 2.429e-23 | A0A5J5ERY1; Alpha/Beta hydrolase protein; Sphaerosporella brunnea; 6.083e-37 | A0A2C5ZFB3; Fungal lipase-like domain-containing protein; Ophiocordyceps australis; 3.472e-33 |
| XANPAGTX0501_005151-T1 | cl05 | Lipase | Non-DGE | 0.83 | 82.60072 | 318 | IPR002921 Fungal lipase-like domain;IPR005592 Mono-/di-acylglycerol lipase, N-terminal;IPR029058 Alpha/Beta hydrolase fold | NA | NA | Non-antimicrobial | 5CH8; Crystal structure of MDLA N225Q mutant form Penicillium cyclopium; 1.01e-27 | 1TIA; AN UNUSUAL BURIED POLAR CLUSTER IN A FAMILY OF FUNGAL LIPASES; 2.47e-23 | A0A151GN20; Fungal lipase-like domain-containing protein; Drechmeria coniospora; 3.859e-27 | A0A4Q0A149; Alpha/Beta hydrolase protein; Dimargaris cristalligena; 2.738e-21 |
| XANPAGTX0501_005200-T1 | cl05 | Lipase | Non-DGE | 0.86 | 88.66610 | 310 | IPR002921 Fungal lipase-like domain;IPR005592 Mono-/di-acylglycerol lipase, N-terminal;IPR029058 Alpha/Beta hydrolase fold | NA | NA | Non-antimicrobial | 1DU4; THE STRUCTURAL ORIGINS OF INTERFACIAL ACTIVATION IN THERMOMYCES (HUMICOLA) LANUGINOSA LIPASE OTHER STRUCTURE DETAILS; 1.208e-31 | 5XK2; Crystal structure of mono- and diacylglycerol lipase from Aspergillus oryzae; 4.332e-31 | M2VDZ6; Fungal lipase-like domain-containing protein; Cochliobolus heterostrophus (strain C5 / ATCC 48332 / race O) (Southern corn leaf blight fungus) (Bipolaris maydis); 1.614e-40 | A0A2T2P6Z2; Alpha/beta-hydrolase; Corynespora cassiicola Philippines; 2.649e-39 |
| XANPAGTX0501_007071-T1 | cl05 | Lipase | Non-DGE | 0.66 | 69.82050 | 604 | IPR002921 Fungal lipase-like domain;IPR029058 Alpha/Beta hydrolase fold | NA | NA | Antimicrobial | NA | NA | A0A1V6U163; triacylglycerol lipase (EC 3.1.1.3) (Autophagy-related protein 15); Penicillium steckii; 6.163e-51 | A0A165GXK6; triacylglycerol lipase (EC 3.1.1.3) (Autophagy-related protein 15); Xylona heveae (strain CBS 132557 / TC161); 1.017e-48 |
| XANPAGTX0501_003746-T1 | cl06 | Carboxylesterase | Non-DGE | 0.92 | 93.16333 | 559 | IPR002018 Carboxylesterase, type B;IPR019819 Carboxylesterase type B, conserved site;IPR019826 Carboxylesterase type B, active site;IPR029058 Alpha/Beta hydrolase fold | NA | S09X | Non-antimicrobial | 1C7I; THERMOPHYLIC PNB ESTERASE; 5.855e-38 | 1QE3; PNB ESTERASE; 2.791e-37 | A0A0D2GVE1; Carboxylic ester hydrolase (EC 3.1.1.-); Fonsecaea pedrosoi CBS 271.37; 7.64e-80 | W9X4S7; Zn(2)-C6 fungal-type domain-containing protein; Cladophialophora psammophila CBS 110553; 1.881e-70 |
| XANPAGTX0501_004372-T1 | cl06 | Carboxylesterase | Upregulated in lichen | 0.91 | 89.42864 | 581 | IPR002018 Carboxylesterase, type B;IPR029058 Alpha/Beta hydrolase fold | NA | S09X | Non-antimicrobial | 1UKC; Crystal Structure of Aspergillus niger EstA; 3.901e-40 | 1LLF; Cholesterol Esterase (Candida Cylindracea) Crystal Structure at 1.4A resolution; 3.298e-35 | A0A1Y2DQ58; Alpha/Beta hydrolase protein; Pseudomassariella vexata; 2.91e-67 | A0A2N3NG78; Carboxylesterase type B domain-containing protein; Lomentospora prolificans; 2.748e-66 |
| XANPAGTX0501_008841-T1 | cl06 | Carboxylesterase | Non-DGE | 0.89 | 87.54931 | 507 | IPR002018 Carboxylesterase, type B;IPR019826 Carboxylesterase type B, active site;IPR029058 Alpha/Beta hydrolase fold | NA | S09X | Non-antimicrobial | 6EMI; Crystal structure of a variant of human butyrylcholinesterase expressed in bacteria.; 1.413e-37 | 2WSL; Aged Form of Human Butyrylcholinesterase Inhibited by Tabun Analogue TA4; 1.622e-36 | W6YBH2; Carboxylic ester hydrolase (EC 3.1.1.-); Cochliobolus carbonum (strain 26-R-13) (Maize leaf spot fungus) (Bipolaris zeicola); 1.318e-76 | A0A0A2IML7; Carboxylic ester hydrolase (EC 3.1.1.-); Penicillium expansum (Blue mold rot fungus); 9.628e-66 |
| XANPAGTX0501_010387-T1 | cl06 | Carboxylesterase | Non-DGE | 0.91 | 89.53768 | 629 | IPR002018 Carboxylesterase, type B;IPR019819 Carboxylesterase type B, conserved site;IPR019826 Carboxylesterase type B, active site;IPR029058 Alpha/Beta hydrolase fold | NA | S09X | Non-antimicrobial | 1UKC; Crystal Structure of Aspergillus niger EstA; 1.105e-40 | 5TYM; alpha-esterase-7 in complex with [3-bromo-5-(pyrrolidin-1-yl)phenyl]borinic acid; 2.15e-28 | A0A2N3NJP6; Carboxylic ester hydrolase (EC 3.1.1.-); Lomentospora prolificans; 1.199e-77 | A0A175W3Y4; Carboxylic ester hydrolase (EC 3.1.1.-); Madurella mycetomatis; 1.271e-77 |
| XANPAGTX0501_004947-T1 | cl07 | Esterase | Non-DGE | 0.75 | 75.97718 | 280 | IPR029058 Alpha/Beta hydrolase fold | NA | NA | Non-antimicrobial | 4Q34; Crystal structure of a putative esterase (BDI_1566) from Parabacteroides distasonis ATCC 8503 at 1.60 A resolution; 7.096e-12 | 8J7J; crystal structure of SulE mutant; 2.396e-10 | A0A2S7R5N2; Alpha beta-hydrolase protein; Rutstroemia sp. NJR-2017a WRK4; 1.305e-26 | A0A5M9J6M4; AB hydrolase-1 domain-containing protein; Monilinia fructicola (Brown rot fungus) (Ciboria fructicola); 5.539e-26 |
| XANPAGTX0501_005390-T1 | cl07 | Esterase | Non-DGE | 0.85 | 82.22738 | 370 | IPR000073 Alpha/beta hydrolase fold-1;IPR029058 Alpha/Beta hydrolase fold | NA | NA | Non-antimicrobial | 7Y0L; SulE-S209A; 6.17e-17 | 8GOY; SulE P44R; 2.948e-16 | A0A5M9MXD6; Uncharacterized protein; Aspergillus tanneri; 1.183e-36 | W3X8Z8; Uncharacterized protein; Pestalotiopsis fici (strain W106-1 / CGMCC3.15140); 1.481e-35 |
| XANPAGTX0501_009613-T1 | cl07 | Esterase | Upregulated in culture | 0.87 | 89.68830 | 411 | IPR000073 Alpha/beta hydrolase fold-1;IPR029058 Alpha/Beta hydrolase fold | NA | NA | Non-antimicrobial | 2WKW; Alcaligenes esterase complexed with product analogue; 2.269e-18 | 2XMR; Crystal structure of human NDRG2 protein provides insight into its role as a tumor suppressor; 1.238e-05 | A0A4S9HIU3; Alpha/beta-hydrolase; Aureobasidium pullulans (Black yeast) (Pullularia pullulans); 3.139e-58 | W3XMF4; AB hydrolase-1 domain-containing protein; Pestalotiopsis fici (strain W106-1 / CGMCC3.15140); 2.594e-56 |
| XANPAGTX0501_009663-T1 | cl07 | Esterase | Non-DGE | 0.87 | 90.03199 | 396 | IPR029058 Alpha/Beta hydrolase fold | NA | NA | Non-antimicrobial | 7Y0L; SulE-S209A; 5.344e-21 | 8J7J; crystal structure of SulE mutant; 6.404e-21 | A0A6G1JNZ9; Alpha/beta-hydrolase; Lentithecium fluviatile CBS 122367; 1.496e-43 | A0A5M9MXD6; Uncharacterized protein; Aspergillus tanneri; 5.64e-43 |
| XANPAGTX0501_002987-T1 | cl08 | Annotations do not match | Non-DGE | 0.9 | 92.13380 | 502 | IPR000073 Alpha/beta hydrolase fold-1;IPR029058 Alpha/Beta hydrolase fold | NA | S33 | Non-antimicrobial | 5UGQ; Crystal Structure of Hip1 (Rv2224c); 7.392e-29 | 5BKM; Crystal Structure of Hip1 (Rv2224c) mutant - S228DHA (dehydroalanine); 1.067e-28 | A0A517LJC5; AB hydrolase-1 domain-containing protein; Venturia effusa; 3.629e-54 | A0A319E729; Uncharacterized protein; Aspergillus sclerotiicarbonarius (strain CBS 121057 / IBT 28362); 5.829e-53 |
| XANPAGTX0501_003285-T1 | cl08 | Annotations do not match | Upregulated in lichen | 0.89 | 91.59657 | 545 | IPR008758 Peptidase S28;IPR029058 Alpha/Beta hydrolase fold;IPR042269 Serine carboxypeptidase S28, SKS domain | NA | S28 | Antimicrobial | 7WAB; Crystal structure of the prolyl endoprotease, PEP, from Aspergillus niger; 3.561e-30 | 3JYH; Human dipeptidyl peptidase DPP7; 2.669e-20 | A0A0J8R059; Uncharacterized protein; Coccidioides immitis RMSCC 3703; 6.685e-63 | A0A6H0XQH2; Serine carboxypeptidase S28; Peltaster fructicola; 1.192e-60 |
| XANPAGTX0501_000182-T1 | cl09 | Peptidase S10P | Non-DGE | 0.88 | 88.12758 | 549 | IPR001563 Peptidase S10, serine carboxypeptidase;IPR008442 Propeptide, carboxypeptidase Y;IPR018202 Serine carboxypeptidase, serine active site;IPR029058 Alpha/Beta hydrolase fold | NA | S10 | Antimicrobial | 1YSC; 2.8 ANGSTROMS STRUCTURE OF YEAST SERINE CARBOXYPEPTIDASE; 5.144e-57 | 1CPY; SITE-DIRECTED MUTAGENESIS ON (SERINE) CARBOXYPEPTIDASE Y FROM YEAST. THE SIGNIFICANCE OF THR 60 AND MET 398 IN HYDROLYSIS AND AMINOLYSIS REACTIONS; 3.598e-56 | A0A1R3S1F9; Carboxypeptidase (EC 3.4.16.-); Aspergillus carbonarius (strain ITEM 5010); 3.931e-87 | A0A7T7BNH1; Carboxypeptidase (EC 3.4.16.-); Penicillium digitatum (Green mold); 1.951e-86 |
| XANPAGTX0501_000540-T1 | cl09 | Peptidase S10P | Non-DGE | 0.88 | 90.25310 | 577 | IPR001563 Peptidase S10, serine carboxypeptidase;IPR018202 Serine carboxypeptidase, serine active site;IPR029058 Alpha/Beta hydrolase fold | NA | S10 | Antimicrobial | 1YSC; 2.8 ANGSTROMS STRUCTURE OF YEAST SERINE CARBOXYPEPTIDASE; 8.707e-35 | 1CPY; SITE-DIRECTED MUTAGENESIS ON (SERINE) CARBOXYPEPTIDASE Y FROM YEAST. THE SIGNIFICANCE OF THR 60 AND MET 398 IN HYDROLYSIS AND AMINOLYSIS REACTIONS; 3.248e-33 | A0A3M7P144; Carboxypeptidase (EC 3.4.16.-); Chaetothyriales sp. CBS 134916; 3.571e-80 | A0A179UWX9; Carboxypeptidase (EC 3.4.16.-); Blastomyces gilchristii (strain SLH14081) (Blastomyces dermatitidis); 1.264e-73 |
| XANPAGTX0501_008146-T1 | cl09 | Peptidase S10P | Upregulated in lichen | 0.88 | 87.83462 | 506 | IPR001563 Peptidase S10, serine carboxypeptidase;IPR018202 Serine carboxypeptidase, serine active site;IPR029058 Alpha/Beta hydrolase fold | NA | S10 | Non-antimicrobial | 4CI9; Crystal structure of cathepsin A, apo-structure; 6.196e-31 | 1IVY; PHYSIOLOGICAL DIMER HPP PRECURSOR; 4.587e-30 | A0A1W5DCK7; Carboxypeptidase (EC 3.4.16.-); Lasallia pustulata; 3.809e-66 | A0A094AVS9; Carboxypeptidase (EC 3.4.16.-); Pseudogymnoascus sp. VKM F-4281 (FW-2241); 2.688e-48 |
| XANPAGTX0501_009239-T1 | cl09 | Peptidase S10P | Non-DGE | 0.86 | 86.90514 | 677 | IPR001563 Peptidase S10, serine carboxypeptidase;IPR018202 Serine carboxypeptidase, serine active site;IPR029058 Alpha/Beta hydrolase fold;IPR033124 Serine carboxypeptidases, histidine active site | NA | S10 | Antimicrobial | 4CIB; crystal structure of cathepsin a, complexed with compound 2; 2.142e-26 | 4CI9; Crystal structure of cathepsin A, apo-structure; 2.6e-25 | A0A364LCY0; Major facilitator superfamily (MFS) profile domain-containing protein; Talaromyces amestolkiae; 1.375e-85 | A0A0A2JXA2; Poly [ADP-ribose] polymerase (PARP) (EC 2.4.2.-); Penicillium expansum (Blue mold rot fungus); 2.939e-85 |
| XANPAGTX0501_009986-T1 | cl09 | Peptidase S10P | Non-DGE | 0.9 | 91.46279 | 551 | IPR001563 Peptidase S10, serine carboxypeptidase;IPR018202 Serine carboxypeptidase, serine active site;IPR029058 Alpha/Beta hydrolase fold | NA | S10 | Antimicrobial | 4MWS; Crystal structure of human PPCA (trigonal crystal form 1); 6.332e-28 | 4CI9; Crystal structure of cathepsin A, apo-structure; 3.404e-27 | A0A1S1VAN8; deleted; ; 4.902e-78 | A0A3M7MD23; Carboxypeptidase (EC 3.4.16.-); Pyrenophora seminiperda CCB06; 2.635e-77 |
| XANPAGTX0501_009724-T1 | cl10 | Pyrethroid Hydrolase and Hydroxynitrile Lyase | Non-DGE | 0.85 | 90.04939 | 295 | IPR000073 Alpha/beta hydrolase fold-1;IPR029058 Alpha/Beta hydrolase fold | NA | NA | Non-antimicrobial | 5Y5R; Crystal structure of a novel Pyrethroid Hydrolase PytH with BIF; 5.077e-16 | 5Y51; Crystal structure of PytH_H230A; 5.776e-16 | A0A1Y1Y4L9; Alpha/beta hydrolase fold-1; Clohesyomyces aquaticus; 1.027e-39 | A0A2V1D9L3; Alpha/beta-hydrolase; Periconia macrospinosa; 1.513e-39 |
| XANPAGTX0501_009860-T1 | cl10 | Pyrethroid Hydrolase and Hydroxynitrile Lyase | Non-DGE | 0.85 | 90.14534 | 294 | IPR000073 Alpha/beta hydrolase fold-1;IPR029058 Alpha/Beta hydrolase fold | NA | NA | Antimicrobial | 5TDX; Resurrected Ancestral Hydroxynitrile Lyase from Flowering Plants; 8.805e-13 | 5Y5V; Crystal structure of a novel Pyrethroid Hydrolase PytH (S78A); 2.03e-11 | A0A2V1D9L3; Alpha/beta-hydrolase; Periconia macrospinosa; 2.057e-39 | A0A1Y1Y4L9; Alpha/beta hydrolase fold-1; Clohesyomyces aquaticus; 3.071e-39 |
| XANPAGTX0501_002310-T1 | cl11 | Lipase | Non-DGE | 0.91 | 92.19912 | 443 | IPR029058 Alpha/Beta hydrolase fold | NA | NA | Non-antimicrobial | 5HDP; Hydrolase StnA mutant - S185A; 5.498e-23 | 5HDF; Hydrolase SeMet-StnA; 3.486e-22 | A0A4S9HNV5; Alpha/beta-hydrolase; Aureobasidium pullulans (Black yeast) (Pullularia pullulans); 1.305e-65 | R1GBW7; Putative alpha beta-hydrolase protein; Botryosphaeria parva (strain UCR-NP2) (Grapevine canker fungus) (Neofusicoccum parvum); 8.157e-52 |
| XANPAGTX0501_003835-T1 | cl11 | Lipase | Non-DGE | 0.85 | 86.10993 | 428 | IPR000073 Alpha/beta hydrolase fold-1;IPR029058 Alpha/Beta hydrolase fold | NA | NA | Antimicrobial | 5HDP; Hydrolase StnA mutant - S185A; 5.02e-25 | 5HDF; Hydrolase SeMet-StnA; 1.597e-24 | A0A2H2ZMS4; Esterase; Trichoderma parareesei (Filamentous fungus); 1.24e-55 | A0A6A5TNI9; Alpha/beta-hydrolase; Byssothecium circinans; 6.672e-54 |
| XANPAGTX0501_005856-T1 | cl11 | Lipase | Non-DGE | 0.87 | 85.57917 | 396 | IPR000073 Alpha/beta hydrolase fold-1;IPR029058 Alpha/Beta hydrolase fold | NA | NA | Antimicrobial | 5HDP; Hydrolase StnA mutant - S185A; 1.598e-21 | 5HDF; Hydrolase SeMet-StnA; 3.803e-21 | A0A165FUN5; AB hydrolase-1 domain-containing protein; Exidia glandulosa HHB12029; 1.962e-31 | A0A4V6S1T3; (4-O-methyl)-D-glucuronate–lignin esterase (EC 3.1.1.117); Antrodiella citrinella; 9.033e-29 |
| XANPAGTX0501_003182-T1 | cl12 | Esterase | Non-DGE | 0.9 | 91.96087 | 469 | IPR005152 Lipase, secreted;IPR022742 Serine aminopeptidase, S33;IPR029058 Alpha/Beta hydrolase fold | NA | NA | Non-antimicrobial | 3H2I; Crystal structure of N228W mutant of the rice cell wall degrading esterase LipA from Xanthomonas oryzae; 1.997e-18 | 3H2J; Crystal structure of the rice cell wall degrading esterase LipA from Xanthomonas oryzae; 4.028e-18 | A0A6A6ULT3; Prolyl aminopeptidase-like protein; Microthyrium microscopicum; 2.63e-58 | A0A178B9N1; Alpha/beta-hydrolase; Stagonospora sp. SRC1lsM3a; 9.082e-53 |
| XANPAGTX0501_009609-T1 | cl12 | Esterase | Upregulated in culture | 0.91 | 92.02805 | 476 | IPR000073 Alpha/beta hydrolase fold-1;IPR005152 Lipase, secreted;IPR029058 Alpha/Beta hydrolase fold | NA | NA | Non-antimicrobial | 3H2J; Crystal structure of the rice cell wall degrading esterase LipA from Xanthomonas oryzae; 1.046e-17 | 3H2G; Crystal structure of a rice cell wall degrading esterase LipA from Xanthomonas oryzae; 1.89e-17 | A0A6A6ULT3; Prolyl aminopeptidase-like protein; Microthyrium microscopicum; 1.231e-54 | A0A178B9N1; Alpha/beta-hydrolase; Stagonospora sp. SRC1lsM3a; 1.413e-50 |
| XANPAGTX0501_002540-T1 | cl13 | No annotation | Non-DGE | 0.9 | 92.84221 | 434 | IPR010520 Esterase FrsA-like;IPR029058 Alpha/Beta hydrolase fold | NA | NA | Antimicrobial | 3FNB; Crystal structure of acylaminoacyl peptidase SMU_737 from Streptococcus mutans UA159; 1.4e-20 | 3FNB; Crystal structure of acylaminoacyl peptidase SMU_737 from Streptococcus mutans UA159; 1.526e-19 | A0A0N1NX87; AB hydrolase-1 domain-containing protein; Phialophora attinorum; 3.535e-54 | A0A5C6G0M3; Peptidase S9 prolyl oligopeptidase catalytic domain-containing protein; Metarhizium rileyi; 1.373e-43 |
| XANPAGTX0501_004433-T1 | cl13 | No annotation | Non-DGE | 0.92 | 94.86553 | 714 | IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain;IPR011042 Six-bladed beta-propeller, TolB-like;IPR011659 WD40-like beta propeller;IPR029058 Alpha/Beta hydrolase fold | NA | S09C | Antimicrobial | 5YZO; Crystal structure of S9 peptidase mutant (S514A) from Deinococcus radiodurans R1; 5.984e-35 | 6IKG; Crystal structure of substrate-bound S9 peptidase (S514A mutant) from Deinococcus radiodurans; 1.509e-34 | A0A4Q4V310; Dipeptidyl-peptidase V; Monosporascus sp. MC13-8B; 0 | A0A3M0W227; Dipeptidyl-peptidase V; Chaetothyriales sp. CBS 134920; 0 |
| XANPAGTX0501_006949-T1 | cl13 | No annotation | Non-DGE | 0.84 | 84.77185 | 329 | IPR000073 Alpha/beta hydrolase fold-1;IPR029058 Alpha/Beta hydrolase fold | NA | S33 | Non-antimicrobial | 6I8W; Crystal structure of a membrane phospholipase A, a novel bacterial virulence factor; 2.061e-14 | 8CKP; X-ray structure of the crystallization-prone form of subfamily III haloalkane dehalogenase DhmeA from Haloferax mediterranei; 4.295e-14 | A0A0D2BFI4; AB hydrolase-1 domain-containing protein; Exophiala spinifera; 2.246e-45 | A0A1N6RDX9; Pimeloyl-ACP methyl ester carboxylesterase; Rhizobium sp. RU20A; 6.038e-23 |
| XANPAGTX0501_003976-T1 | cl14 | No annotation | Non-DGE | 0.79 | 79.28147 | 509 | NA | NA | NA | Antimicrobial | NA | NA | A0A1Y2V553; Uncharacterized protein; Hypoxylon sp. CO27-5; 4.332e-45 | A0A6A6B2B8; Uncharacterized protein; Aplosporella prunicola CBS 121167; 2.514e-42 |
| XANPAGTX0501_006270-T1 | cl14 | No annotation | Non-DGE | 0.57 | 55.33792 | 542 | NA | NA | NA | Below pLDDT threshold | NA | NA | A0A5N6L017; Uncharacterized protein; Carpinus fangiana; 7.191e-07 | A0A2B7X216; Uncharacterized protein; Polytolypa hystricis UAMH7299; 9.167e-07 |
| XANPAGTX0501_000377-T1 | cl15 | No annotation | Non-DGE | 0.72 | 71.00979 | 284 | NA | NA | NA | Antimicrobial | NA | NA | A0A6G1LIW3; Uncharacterized protein; Teratosphaeria nubilosa; 2.048e-06 | X0BWY9; Uncharacterized protein; Fusarium oxysporum f. sp. raphani 54005; 2.597e-06 |
| XANPAGTX0501_004983-T1 | cl15 | No annotation | Upregulated in lichen | 0.53 | 48.55580 | 305 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_005038-T1 | cl15 | No annotation | Non-DGE | 0.58 | 56.47559 | 535 | NA | NA | NA | Below pLDDT threshold | NA | NA | T0KPG9; Uncharacterized protein; Colletotrichum gloeosporioides (strain Cg-14) (Anthracnose fungus) (Glomerella cingulata); 1.935e-12 | A0A3M9XZ81; Uncharacterized protein; Verticillium nonalfalfae; 5.127e-11 |
| XANPAGTX0501_005319-T1 | cl15 | No annotation | Non-DGE | 0.75 | 72.21204 | 506 | NA | NA | NA | Antimicrobial | NA | NA | A0A0G4KS37; Uncharacterized protein; Verticillium longisporum; 3.838e-14 | A0A4R8T4G7; Uncharacterized protein; Colletotrichum sidae; 8.489e-13 |
| XANPAGTX0501_005320-T1 | cl15 | No annotation | Non-DGE | 0.64 | 63.34690 | 478 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_006348-T1 | cl15 | No annotation | Non-DGE | 0.58 | 61.99405 | 447 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_006926-T1 | cl15 | No annotation | Upregulated in culture | 0.71 | 71.66184 | 425 | NA | NA | NA | Antimicrobial | NA | NA | NA | NA |
| XANPAGTX0501_008429-T1 | cl15 | No annotation | Upregulated in lichen | 0.78 | 77.60765 | 243 | NA | NA | NA | Non-antimicrobial | NA | NA | NA | NA |
| XANPAGTX0501_000646-T1 | cl16 | Ribonuclease/ribotoxin | Non-DGE | 0.74 | 80.19038 | 182 | IPR016191 Ribonuclease/ribotoxin | NA | NA | Non-antimicrobial | 1FUT; CRYSTAL STRUCTURES OF RIBONUCLEASE F1 OF FUSARIUM MONILIFORME IN ITS FREE FORM AND IN COMPLEX WITH 2’GMP; 1.408e-05 | NA | A0A0K8LLL5; deleted; ; 1.111e-06 | A0A0K6G181; Uncharacterized protein; Rhizoctonia solani; 1.426e-06 |
| XANPAGTX0501_007281-T1 | cl16 | Ribonuclease/ribotoxin | Non-DGE | 0.74 | 87.60496 | 139 | IPR000026 Guanine-specific ribonuclease N1/T1/U2;IPR016191 Ribonuclease/ribotoxin | NA | NA | Antimicrobial | 1I3F; Ribonuclease T1 V89S mutant; 2.928e-15 | 1TRP; X-RAY CRYSTALLOGRAPHIC AND CALORIMERIC STUDIES OF THE EFFECTS OF THE MUTATION TRP 59 TYR IN RIBONUCLEASE T1; 6.326e-15 | W9XZU6; ribonuclease T1 (EC 4.6.1.24); Capronia epimyces CBS 606.96; 6.062e-17 | A0A1C1CET9; ribonuclease T1 (EC 4.6.1.24); Cladophialophora carrionii; 4.159e-16 |
| XANPAGTX0501_002596-T1 | cl17 | Peptidase S53 | Non-DGE | 0.9 | 89.73216 | 619 | IPR000209 Peptidase S8/S53 domain;IPR015366 Peptidase S53, activation domain;IPR023828 Peptidase S8, subtilisin, Ser-active site;IPR030400 Sedolisin domain;IPR036852 Peptidase S8/S53 domain superfamily | NA | S53 | Non-antimicrobial | 3EDY; Crystal Structure of the Precursor Form of Human Tripeptidyl-Peptidase 1; 4.498e-49 | 3EE6; Crystal Structure Analysis of Tripeptidyl peptidase -I; 9.796e-48 | A0A6G1I2G3; tripeptidyl-peptidase II (EC 3.4.14.10); Trichodelitschia bisporula; 3.736e-78 | A0A164QKC3; tripeptidyl-peptidase II (EC 3.4.14.10); Sistotremastrum niveocremeum HHB9708; 2.151e-73 |
| XANPAGTX0501_003328-T1 | cl17 | Peptidase S53 | Non-DGE | 0.84 | 87.49923 | 612 | IPR015366 Peptidase S53, activation domain;IPR030400 Sedolisin domain;IPR036852 Peptidase S8/S53 domain superfamily | NA | S53 | Non-antimicrobial | 3EDY; Crystal Structure of the Precursor Form of Human Tripeptidyl-Peptidase 1; 6.506e-53 | 3EE6; Crystal Structure Analysis of Tripeptidyl peptidase -I; 9.783e-52 | A1D7F7; tripeptidyl-peptidase II (EC 3.4.14.10); Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus); 1.43e-76 | A0A1V8T4J3; Peptidase S53 domain-containing protein; Rachicladosporium antarcticum; 4.12e-50 |
| XANPAGTX0501_002543-T1 | cl18 | Match to effector from Zymoseptoria | Upregulated in lichen | 0.64 | 67.46685 | 200 | NA | NA | NA | Antimicrobial | NA | NA | A0A5M8PQZ5; Uncharacterized protein; Lasallia pustulata; 2.679e-09 | A0A5M8PHA6; Uncharacterized protein; Lasallia pustulata; 1.102e-08 |
| XANPAGTX0501_002595-T1 | cl18 | Match to effector from Zymoseptoria | Non-DGE | 0.62 | 57.62480 | 229 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_003855-T1 | cl18 | Match to effector from Zymoseptoria | Non-DGE | 0.68 | 73.40631 | 195 | NA | NA | NA | Non-antimicrobial | NA | NA | A0A5M8PQF4; Uncharacterized protein; Lasallia pustulata; 2.25e-07 | A0A5M8PC24; Uncharacterized protein; Lasallia pustulata; 3.473e-05 |
| XANPAGTX0501_004956-T1 | cl18 | Match to effector from Zymoseptoria | Upregulated in lichen | 0.62 | 61.62803 | 188 | NA | NA | NA | Below pLDDT threshold | NA | NA | A0A5M8Q4D1; Uncharacterized protein; Lasallia pustulata; 0.0002609 | A0A5M8Q1J0; Uncharacterized protein; Lasallia pustulata; 0.0007029 |
| XANPAGTX0501_005641-T1 | cl18 | Match to effector from Zymoseptoria | Upregulated in lichen | 0.66 | 73.20612 | 209 | NA | NA | NA | Non-antimicrobial | NA | NA | A0A1W5CSP5; Cytidine deaminase-like; Lasallia pustulata; 2.034e-06 | A0A5M8PZ52; Uncharacterized protein; Lasallia pustulata; 1.171e-05 |
| XANPAGTX0501_008683-T1 | cl18 | Match to effector from Zymoseptoria | Upregulated in lichen | 0.71 | 76.60421 | 209 | NA | NA | NA | Non-antimicrobial | NA | NA | A0A1W5CSP5; Cytidine deaminase-like; Lasallia pustulata; 1.442e-08 | A0A5M8PR05; Uncharacterized protein; Lasallia pustulata; 1.433e-07 |
| XANPAGTX0501_000644-T1 | cl19 | No annotation | Non-DGE | 0.73 | 73.47119 | 236 | NA | NA | NA | Non-antimicrobial | NA | NA | A0A364MAI2; Ecp2 effector protein domain-containing protein; Aspergillus flavus; 4.915e-08 | A0A084FV09; Ecp2 effector protein domain-containing protein; Pseudallescheria apiosperma (Scedosporium apiospermum); 1.771e-07 |
| XANPAGTX0501_007888-T1 | cl19 | No annotation | Non-DGE | 0.51 | 51.87602 | 166 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_007976-T1 | cl19 | No annotation | Upregulated in lichen | 0.54 | 55.04935 | 309 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_008764-T1 | cl19 | No annotation | Non-DGE | 0.64 | 62.55342 | 243 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_000439-T1 | cl20 | No annotation | Non-DGE | 0.63 | 67.11952 | 167 | NA | NA | NA | Antimicrobial | NA | NA | A0A060SPR1; Uncharacterized protein; Pycnoporus cinnabarinus (Cinnabar-red polypore) (Trametes cinnabarina); 1.146e-06 | NA |
| XANPAGTX0501_000698-T1 | cl20 | No annotation | Non-DGE | 0.54 | 55.60140 | 200 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_002722-T1 | cl20 | No annotation | Non-DGE | 0.54 | 63.87725 | 193 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_007377-T1 | cl20 | No annotation | Non-DGE | 0.61 | 59.38955 | 178 | NA | NA | NA | Below pLDDT threshold | NA | NA | A0A060SPR1; Uncharacterized protein; Pycnoporus cinnabarinus (Cinnabar-red polypore) (Trametes cinnabarina); 9.237e-07 | NA |
| XANPAGTX0501_008667-T1 | cl20 | No annotation | Non-DGE | 0.71 | 75.29108 | 166 | NA | NA | NA | Non-antimicrobial | NA | NA | A0A094A1V4; Ecp2 effector protein domain-containing protein; Pseudogymnoascus sp. VKM F-4281 (FW-2241); 1.342e-10 | B8M3Y5; Ecp2 effector protein domain-containing protein; Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006) (Penicillium stipitatum); 5.448e-10 |
| XANPAGTX0501_010200-T1 | cl20 | No annotation | Non-DGE | 0.7 | 72.32185 | 173 | NA | NA | NA | Non-antimicrobial | NA | NA | A0A094A1V4; Ecp2 effector protein domain-containing protein; Pseudogymnoascus sp. VKM F-4281 (FW-2241); 1.676e-10 | B8M3Y5; Ecp2 effector protein domain-containing protein; Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006) (Penicillium stipitatum); 2.043e-07 |
| XANPAGTX0501_010384-T1 | cl20 | No annotation | Non-DGE | 0.75 | 72.57189 | 344 | NA | NA | NA | Non-antimicrobial | NA | NA | A0A5M8Q3Y7; Uncharacterized protein; Lasallia pustulata; 0.0006552 | NA |
| XANPAGTX0501_000479-T1 | cl21 | Killer toxin | Non-DGE | 0.56 | 55.79035 | 202 | IPR015131 Killer toxin, Kp4 | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_003600-T1 | cl21 | Killer toxin | Non-DGE | 0.82 | 90.35133 | 143 | IPR011329 Killer toxin Kp4/SMK;IPR015131 Killer toxin, Kp4 | NA | NA | Non-antimicrobial | 1KPT; STRUCTURE AND FUNCTION OF A VIRALLY ENCODED FUNGAL TOXIN FROM USTILAGO MAYDIS: A FUNGAL AND MAMMALIAN CALCIUM CHANNEL INHIBITOR; 2.3e-09 | NA | A9TFY6; deleted; ; 5.422e-14 | A0A1B8CHQ2; Killer toxin Kp4 domain-containing protein; Pseudogymnoascus sp. WSF 3629; 3.199e-13 |
| XANPAGTX0501_003928-T1 | cl21 | Killer toxin | Non-DGE | 0.66 | 67.63112 | 188 | IPR011329 Killer toxin Kp4/SMK;IPR015131 Killer toxin, Kp4 | NA | NA | Non-antimicrobial | NA | NA | F9F9K8; Killer toxin Kp4 domain-containing protein; Fusarium oxysporum (strain Fo5176) (Fusarium vascular wilt); 5.914e-07 | A0A1B8CHQ2; Killer toxin Kp4 domain-containing protein; Pseudogymnoascus sp. WSF 3629; 7.571e-07 |
| XANPAGTX0501_005492-T1 | cl21 | Killer toxin | Non-DGE | 0.68 | 68.89830 | 176 | IPR011329 Killer toxin Kp4/SMK;IPR015131 Killer toxin, Kp4 | NA | NA | Non-antimicrobial | NA | NA | A0A6A5ZMZ9; Killer toxin Kp4/SMK; Lophiotrema nucula; 9.134e-06 | NA |
| XANPAGTX0501_009135-T1 | cl21 | Killer toxin | Upregulated in lichen | 0.66 | 76.66139 | 187 | IPR011329 Killer toxin Kp4/SMK;IPR015131 Killer toxin, Kp4 | NA | NA | Non-antimicrobial | NA | NA | A0A6A6ELN5; Killer toxin Kp4 domain-containing protein; Zopfia rhizophila CBS 207.26; 1.3e-06 | A0A094D0J3; Killer toxin Kp4 domain-containing protein; Pseudogymnoascus sp. VKM F-4515 (FW-2607); 6.152e-06 |
| XANPAGTX0501_003287-T1 | cl22 | No annotation | Upregulated in lichen | 0.73 | 80.95278 | 144 | NA | NA | NA | Non-antimicrobial | NA | NA | A0A161W712; Uncharacterized protein; Colletotrichum tofieldiae; 3.962e-09 | A0A167B5E5; Uncharacterized protein; Colletotrichum incanum; 2.258e-08 |
| XANPAGTX0501_005361-T1 | cl22 | No annotation | Upregulated in lichen | 0.65 | 74.83741 | 116 | NA | NA | NA | Non-antimicrobial | NA | NA | A0A0G2EKX1; Uncharacterized protein; Diplodia seriata; 5.77e-07 | A0A6A6BTW9; Ecp2 effector protein domain-containing protein; Aplosporella prunicola CBS 121167; 2.452e-06 |
| XANPAGTX0501_002191-T1 | cl23 | No annotation | Upregulated in lichen | 0.64 | 64.15772 | 197 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_007255-T1 | cl23 | No annotation | Non-DGE | 0.51 | 59.76941 | 387 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_010210-T1 | cl23 | No annotation | Non-DGE | 0.51 | 59.76941 | 387 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_000051-T1 | cl24 | Match to effector from Zymoseptoria | Upregulated in lichen | 0.72 | 74.54809 | 209 | NA | NA | NA | Antimicrobial | NA | NA | A0A6A5VL10; Cyanovirin-N domain-containing protein; Bimuria novae-zelandiae CBS 107.79; 0.0006847 | NA |
| XANPAGTX0501_000388-T1 | cl24 | Match to effector from Zymoseptoria | Non-DGE | 0.62 | 66.82851 | 181 | NA | NA | NA | Antimicrobial | NA | NA | NA | NA |
| XANPAGTX0501_000861-T1 | cl24 | Match to effector from Zymoseptoria | Non-DGE | 0.73 | 74.76842 | 196 | NA | NA | NA | Non-antimicrobial | NA | NA | NA | NA |
| XANPAGTX0501_001970-T1 | cl24 | Match to effector from Zymoseptoria | Upregulated in lichen | 0.74 | 78.09834 | 199 | NA | NA | NA | Non-antimicrobial | NA | NA | A0A7U2HV09; Ecp2 effector protein domain-containing protein; Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Parastagonospora nodorum); 0.0003166 | A0A132B635; Uncharacterized protein; Mollisia scopiformis (Conifer needle endophyte fungus) (Phialocephala scopiformis); 0.000469 |
| XANPAGTX0501_003296-T1 | cl24 | Match to effector from Zymoseptoria | Non-DGE | 0.73 | 79.00464 | 209 | NA | NA | NA | Non-antimicrobial | NA | NA | A0A3A2ZMW6; Ecp2 effector protein domain-containing protein; Aspergillus sclerotialis; 0.0007546 | NA |
| XANPAGTX0501_005376-T1 | cl24 | Match to effector from Zymoseptoria | Non-DGE | 0.68 | 76.84675 | 191 | NA | NA | NA | Non-antimicrobial | NA | NA | A0A1Y2W2A6; Ig-like domain-containing protein; Hypoxylon sp. CI-4A; 0.0001963 | NA |
| XANPAGTX0501_006142-T1 | cl24 | Match to effector from Zymoseptoria | Upregulated in lichen | 0.68 | 72.71696 | 171 | NA | NA | NA | Non-antimicrobial | NA | NA | NA | NA |
| XANPAGTX0501_006349-T1 | cl24 | Match to effector from Zymoseptoria | Upregulated in lichen | 0.7 | 75.74075 | 226 | NA | NA | NA | Non-antimicrobial | NA | NA | NA | NA |
| XANPAGTX0501_007288-T1 | cl24 | Match to effector from Zymoseptoria | Non-DGE | 0.61 | 72.42179 | 319 | IPR002889 Carbohydrate-binding WSC | AA2, AA5 | NA | Antimicrobial | 7PZ2; Structure of the mechanosensor domain of Wsc1 from Saccharomyces cerevisiae; 1.55e-07 | 6SNW; Structure of Coxsackievirus A10 complexed with its receptor KREMEN1; 4.531e-05 | A0A1Y2LJZ5; WSC domain-containing protein; Epicoccum nigrum (Soil fungus) (Epicoccum purpurascens); 2.401e-08 | D8LDH2; WSC domain-containing protein; Ectocarpus siliculosus (Brown alga) (Conferva siliculosa); 4.264e-08 |
| XANPAGTX0501_000410-T1 | cl24a | Match to effector from Zymoseptoria | Non-DGE | 0.77 | 83.43706 | 293 | NA | NA | NA | Non-antimicrobial | NA | NA | NA | NA |
| XANPAGTX0501_002475-T1 | cl24a | Match to effector from Zymoseptoria | Non-DGE | 0.77 | 81.77143 | 286 | NA | NA | NA | Non-antimicrobial | NA | NA | NA | NA |
| XANPAGTX0501_005533-T1 | cl24a | Match to effector from Zymoseptoria | Upregulated in lichen | 0.74 | 79.01963 | 325 | NA | NA | NA | Non-antimicrobial | NA | NA | NA | NA |
| XANPAGTX0501_006379-T1 | cl24a | Match to effector from Zymoseptoria | Non-DGE | 0.69 | 74.20991 | 326 | NA | NA | NA | Non-antimicrobial | NA | NA | NA | NA |
| XANPAGTX0501_007272-T1 | cl24a | Match to effector from Zymoseptoria | Upregulated in lichen | 0.79 | 84.63390 | 287 | NA | NA | NA | Antimicrobial | NA | NA | Q0UJL2; Ecp2 effector protein domain-containing protein; Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Parastagonospora nodorum); 0.0008085 | A0A165A189; Ecp2 effector protein domain-containing protein; Xylona heveae (strain CBS 132557 / TC161); 0.0008581 |
| XANPAGTX0501_008015-T1 | cl24a | Match to effector from Zymoseptoria | Non-DGE | 0.73 | 78.45364 | 324 | NA | NA | NA | Non-antimicrobial | NA | NA | NA | NA |
| XANPAGTX0501_009178-T1 | cl24a | Match to effector from Zymoseptoria | Non-DGE | 0.77 | 81.47093 | 302 | NA | NA | NA | Non-antimicrobial | NA | NA | A0A175WEN3; Uncharacterized protein; Madurella mycetomatis; 0.0002072 | A0A165A189; Ecp2 effector protein domain-containing protein; Xylona heveae (strain CBS 132557 / TC161); 0.0003844 |
| XANPAGTX0501_009189-T1 | cl24a | Match to effector from Zymoseptoria | Upregulated in lichen | 0.65 | 67.62702 | 171 | NA | NA | NA | Non-antimicrobial | NA | NA | NA | NA |
| XANPAGTX0501_009340-T1 | cl24a | Match to effector from Zymoseptoria | Upregulated in lichen | 0.64 | 67.21936 | 266 | NA | NA | NA | Non-antimicrobial | NA | NA | A0A6A5VL10; Cyanovirin-N domain-containing protein; Bimuria novae-zelandiae CBS 107.79; 0.0007672 | NA |
| XANPAGTX0501_009690-T1 | cl24a | Match to effector from Zymoseptoria | Upregulated in lichen | 0.63 | 65.94845 | 328 | NA | NA | NA | Non-antimicrobial | NA | NA | NA | NA |
| XANPAGTX0501_010665-T1 | cl24a | Match to effector from Zymoseptoria | Non-DGE | 0.76 | 77.92679 | 296 | NA | NA | NA | Non-antimicrobial | NA | NA | NA | NA |
| XANPAGTX0501_003203-T1 | cl25 | Beta lactamase | Non-DGE | 0.9 | 89.68095 | 465 | IPR001466 Beta-lactamase-related;IPR012338 Beta-lactamase/transpeptidase-like | NA | S12 | Antimicrobial | 4GDN; Structure of FmtA-like protein; 5.787e-15 | 4GDN; Structure of FmtA-like protein; 2.3e-14 | A0A428PJV0; Beta-lactamase-related domain-containing protein; Fusarium duplospermum; 4.281e-48 | A0A2V1BZZ6; Beta-lactamase/transpeptidase-like protein; Cadophora sp. DSE1049; 7.489e-37 |
| XANPAGTX0501_008641-T1 | cl25 | Beta lactamase | Non-DGE | 0.9 | 90.17461 | 553 | IPR001466 Beta-lactamase-related;IPR012338 Beta-lactamase/transpeptidase-like;IPR021860 Peptidase S12, Pab87-related, C-terminal | NA | S12 | Antimicrobial | 7SPN; Crystal structure of IS11, a thermophilic esterase; 2.129e-27 | 1PW8; Covalent Acyl Enzyme Complex Of The R61 DD-Peptidase with A Highly Specific Cephalosporin; 8.092e-20 | A0A6A6W745; Beta-lactamase/transpeptidase-like protein; Pseudovirgaria hyperparasitica; 6.39e-64 | A0A1W5CZ75; Peptidase S12, Pab87-related, C-terminal; Lasallia pustulata; 1.293e-63 |
| XANPAGTX0501_000306-T1 | cl26 | DUF3455 | Upregulated in culture | 0.82 | 82.46790 | 276 | IPR021851 Protein of unknown function DUF3455 | NA | NA | Non-antimicrobial | NA | NA | A0A1W5D603; Malate dehydrogenase; Lasallia pustulata; 7.134e-22 | A0A6G1G1Q5; Malate dehydrogenase; Eremomyces bilateralis CBS 781.70; 1.618e-21 |
| XANPAGTX0501_003469-T1 | cl26 | DUF3455 | Non-DGE | 0.79 | 86.94504 | 240 | IPR021851 Protein of unknown function DUF3455 | NA | NA | Antimicrobial | NA | NA | A0A1W5CS07; Malate dehydrogenase; Lasallia pustulata; 1.979e-23 | A0A2T6ZAT9; Uncharacterized protein; Tuber borchii (White truffle); 6.239e-18 |
| XANPAGTX0501_005365-T1 | cl27 | Cetoacetate decarboxylase | Non-DGE | 0.85 | 85.17466 | 309 | NA | NA | NA | Non-antimicrobial | NA | NA | U1HXP1; Uncharacterized protein; Endocarpon pusillum (strain Z07020 / HMAS-L-300199) (Lichen-forming fungus); 9.683e-33 | A0A7C8JJ05; Uncharacterized protein; Orbilia oligospora (Nematode-trapping fungus) (Arthrobotrys oligospora); 2.491e-17 |
| XANPAGTX0501_007902-T1 | cl27 | Cetoacetate decarboxylase | Non-DGE | 0.82 | 82.39059 | 323 | NA | NA | NA | Non-antimicrobial | 3CMB; Crystal structure of acetoacetate decarboxylase (YP_001047042.1) from Methanoculleus marisnigri JR1 at 1.60 A resolution; 2.758e-05 | NA | A0A094IDM6; Peptidase A1 domain-containing protein; Pseudogymnoascus sp. VKM F-4520 (FW-2644); 5.761e-28 | A0A093ZEF1; Acetoacetate decarboxylase; Pseudogymnoascus sp. VKM F-4246; 1.242e-26 |
| XANPAGTX0501_005675-T1 | cl28 | Mettalopeptidase | Upregulated in lichen | 0.88 | 91.35971 | 280 | IPR008754 Peptidase M43, pregnancy-associated plasma-A;IPR024079 Metallopeptidase, catalytic domain superfamily | NA | M43B | Non-antimicrobial | 7UFG; Cryo-EM structure of PAPP-A in complex with IGFBP5; 1.244e-09 | 7Y5N; Structure of 1:1 PAPP-A.ProMBP complex(half map); 4.116e-09 | A0A2P8ADR0; Extracellular metalloprotease-4; Elsinoe australis; 6.434e-32 | A0A0G2E8P6; Putative metalloprotease 1; Diplodia seriata; 5.14e-31 |
| XANPAGTX0501_008269-T1 | cl28 | Mettalopeptidase | Non-DGE | 0.78 | 80.12037 | 300 | IPR001506 Peptidase M12A;IPR006026 Peptidase, metallopeptidase;IPR024079 Metallopeptidase, catalytic domain superfamily | NA | M12A | Non-antimicrobial | 3EDG; Crystal structure of bone morphogenetic protein 1 protease domain; 3.559e-12 | 3VTG; High choriolytic enzyme 1 (HCE-1), a hatching enzyme zinc-protease from Oryzias latipes (Medaka fish); 4.882e-12 | A0A6A5KBT9; Zincin; Decorospora gaudefroyi; 1.18e-18 | A0A177D3J4; Peptidase metallopeptidase domain-containing protein; Alternaria alternata (Alternaria rot fungus) (Torula alternata); 1.426e-18 |
| XANPAGTX0501_000709-T1 | cl29 | Extracellular membrane protein | Non-DGE | 0.57 | 66.07068 | 369 | IPR008427 Extracellular membrane protein, CFEM domain | NA | NA | Non-antimicrobial | NA | NA | NA | NA |
| XANPAGTX0501_007274-T1 | cl29 | Extracellular membrane protein | Non-DGE | 0.6 | 69.00925 | 268 | NA | NA | NA | Non-antimicrobial | NA | NA | NA | NA |
| XANPAGTX0501_009181-T1 | cl29 | Extracellular membrane protein | Non-DGE | 0.68 | 70.78173 | 260 | IPR008427 Extracellular membrane protein, CFEM domain | NA | NA | Non-antimicrobial | NA | NA | NA | NA |
| XANPAGTX0501_009311-T1 | cl29 | Extracellular membrane protein | Upregulated in lichen | 0.59 | 64.72571 | 287 | IPR008427 Extracellular membrane protein, CFEM domain | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_000850-T1 | cl30 | No annotation | Upregulated in culture | 0.57 | 75.66208 | 192 | NA | NA | NA | Antimicrobial | NA | NA | J3PGZ1; Uncharacterized protein; Gaeumannomyces tritici (strain R3-111a-1) (Wheat and barley take-all root rot fungus) (Gaeumannomyces graminis var. tritici); 0.0002212 | A0A6G1ITF1; Carbohydrate-binding module family 18 protein; Lentithecium fluviatile CBS 122367; 0.0008497 |
| XANPAGTX0501_003101-T1 | cl30 | No annotation | Non-DGE | 0.52 | 66.07706 | 126 | NA | NA | NA | Non-antimicrobial | NA | NA | NA | NA |
| XANPAGTX0501_007884-T1 | cl30 | No annotation | Non-DGE | 0.73 | 76.02150 | 917 | IPR005151 Tail specific protease;IPR029045 ClpP/crotonase-like domain superfamily | NA | NA | Non-antimicrobial | 4QL6; Structure of C. trachomatis CT441; 7.683e-05 | NA | A0A7R7XK62; Tail specific protease domain-containing protein; Aspergillus puulaauensis; 3.654e-74 | A0A6J3MGP7; Tail specific protease domain-containing protein; Dissoconium aciculare CBS 342.82; 2.506e-71 |
| XANPAGTX0501_007275-T1 | cl31 | No annotation | Non-DGE | 0.76 | 88.21626 | 251 | IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily | GH24 | NA | Antimicrobial | NA | NA | E5QZM3; D-alanyl-D-alanine carboxypeptidase; Arthroderma gypseum (strain ATCC MYA-4604 / CBS 118893) (Microsporum gypseum); 2.24e-33 | J3KFN9; Secreted protein; Coccidioides immitis (strain RS) (Valley fever fungus); 1.87e-31 |
| XANPAGTX0501_009038-T1 | cl31 | No annotation | Non-DGE | 0.58 | 72.22559 | 739 | NA | NA | NA | Antimicrobial | NA | NA | A0A436ZYR3; Uncharacterized protein; Arthrobotrys flagrans; 2.304e-40 | A0A6A6QP31; Uncharacterized protein; Lophium mytilinum; 1.441e-33 |
| XANPAGTX0501_010470-T1 | cl31 | No annotation | Upregulated in lichen | 0.59 | 83.84567 | 268 | IPR002196 Glycoside hydrolase, family 24;IPR023346 Lysozyme-like domain superfamily;IPR033907 Endolysin/autolysin;IPR034690 Endolysin T4 type | GH24 | NA | Antimicrobial | 6ET6; Crystal structure of muramidase from Acinetobacter baumannii AB 5075UW prophage; 6.681e-12 | 6H9D; Muramidase domain of SpmX from Asticaccaulis excentricus; 2.291e-11 | A0A5N6J8L9; lysozyme (EC 3.2.1.17); Aspergillus minisclerotigenes; 1.735e-16 | A0A8B6S7C1; deleted; ; 4.096e-10 |
| XANPAGTX0501_010734-T1 | cl31 | No annotation | Non-DGE | 0.68 | 86.89559 | 254 | IPR000064 Endopeptidase, NLPC/P60 domain;IPR038765 Papain-like cysteine peptidase superfamily | NA | C40 | Antimicrobial | 4HPE; Crystal structure of a putative cell wall hydrolase (CD630_03720) from Clostridium difficile 630 at 2.38 A resolution; 3.831e-08 | 6BIQ; Structure of NlpC2 from Trichomonas vaginalis; 1.965e-07 | A0A0U1M172; NlpC/P60 domain-containing protein; Talaromyces islandicus (Penicillium islandicum); 1.076e-24 | A0A397GAT8; NlpC/P60 domain-containing protein; Aspergillus thermomutatus; 2.113e-23 |
| XANPAGTX0501_000452-T1 | cl32 | Mettalopeptidase | Non-DGE | 0.73 | 74.09979 | 289 | NA | NA | NA | Antimicrobial | NA | NA | NA | NA |
| XANPAGTX0501_001785-T1 | cl32 | Mettalopeptidase | Non-DGE | 0.71 | 82.63160 | 307 | IPR024079 Metallopeptidase, catalytic domain superfamily;IPR029482 Putative peptidase domain, HRXXH | NA | NA | Non-antimicrobial | 2X3B; AsaP1 inactive mutant E294A, an extracellular toxic zinc metalloendopeptidase; 4.415e-06 | 2X3B; AsaP1 inactive mutant E294A, an extracellular toxic zinc metalloendopeptidase; 4.902e-06 | A0A5N6TXD9; Putative peptidase domain-containing protein; Aspergillus avenaceus; 4.531e-30 | A0A0D2G5Q1; Putative peptidase domain-containing protein; Rhinocladiella mackenziei CBS 650.93; 2.994e-28 |
| XANPAGTX0501_002741-T1 | cl32 | Mettalopeptidase | Non-DGE | 0.69 | 70.91667 | 309 | NA | NA | NA | Non-antimicrobial | NA | NA | Q0UCJ2; Neutral protease 2 homolog SNOG_10522 (EC 3.4.24.39) (Deuterolysin SNOG_10522); Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Parastagonospora nodorum); 3.274e-05 | A0A3E2HK57; Uncharacterized protein; Scytalidium lignicola (Hyphomycete); 3.274e-05 |
| XANPAGTX0501_002960-T1 | cl32 | Mettalopeptidase | Non-DGE | 0.73 | 74.64852 | 344 | NA | NA | NA | Antimicrobial | NA | NA | G8S6Y6; Peptidyl-Lys metalloendopeptidase (EC 3.4.24.20); Actinoplanes sp. (strain ATCC 31044 / CBS 674.73 / SE50/110); 0.0001734 | A0A820QVP5; Lysine-specific metallo-endopeptidase domain-containing protein; Rotaria sp. Silwood2; 0.0002052 |
| XANPAGTX0501_004133-T1 | cl32 | Mettalopeptidase | Non-DGE | 0.78 | 80.51130 | 293 | NA | NA | NA | Non-antimicrobial | NA | NA | A0A2C5YVE0; deuterolysin (EC 3.4.24.39); Ophiocordyceps australis; 0.0006721 | NA |
| XANPAGTX0501_006381-T1 | cl32 | Mettalopeptidase | Non-DGE | 0.82 | 83.73197 | 300 | IPR024079 Metallopeptidase, catalytic domain superfamily | NA | NA | Non-antimicrobial | NA | NA | A0A6A5YKP2; Lysine-specific metallo-endopeptidase domain-containing protein; Lophiotrema nucula; 3.617e-30 | B2AKP7; Podospora anserina S mat+ genomic DNA chromosome 5, supercontig 9; Podospora anserina (strain S / ATCC MYA-4624 / DSM 980 / FGSC 10383) (Pleurage anserina); 3.832e-28 |
| XANPAGTX0501_006429-T1 | cl32 | Mettalopeptidase | Non-DGE | 0.86 | 86.16997 | 308 | NA | NA | NA | Antimicrobial | NA | NA | A0A6A6J4Z3; Lysine-specific metallo-endopeptidase domain-containing protein; Trematosphaeria pertusa; 2.553e-24 | A0A2J6T3S3; Lysine-specific metallo-endopeptidase domain-containing protein; Hyaloscypha bicolor E; 4.036e-24 |
| XANPAGTX0501_007985-T1 | cl32 | Mettalopeptidase | Upregulated in culture | 0.71 | 68.78266 | 320 | NA | NA | NA | Antimicrobial | NA | NA | A0A7G5IQH8; Neutral protease 2 (EC 3.4.24.39) (Deuterolysin); Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357 / JCM 12722 / SRRC 167); 6.802e-05 | A0A5N6WVU1; Neutral protease 2 (EC 3.4.24.39) (Deuterolysin); Aspergillus sergii; 0.0001065 |
| XANPAGTX0501_009743-T1 | cl32 | Mettalopeptidase | Non-DGE | 0.68 | 65.87238 | 324 | IPR024079 Metallopeptidase, catalytic domain superfamily | NA | NA | Antimicrobial | NA | NA | A0A7R7XV22; Lysine-specific metallo-endopeptidase domain-containing protein; Aspergillus puulaauensis; 4.849e-05 | NA |
| XANPAGTX0501_009833-T1 | cl32 | Mettalopeptidase | Non-DGE | 0.84 | 82.80289 | 256 | IPR024079 Metallopeptidase, catalytic domain superfamily | NA | NA | Antimicrobial | NA | NA | A0A151GRG3; deuterolysin (EC 3.4.24.39); Drechmeria coniospora; 3.762e-06 | T5ACR4; deuterolysin (EC 3.4.24.39); Ophiocordyceps sinensis (strain Co18 / CGMCC 3.14243) (Yarsagumba caterpillar fungus) (Hirsutella sinensis); 1.02e-05 |
| XANPAGTX0501_010126-T2 | cl32 | Mettalopeptidase | Upregulated in culture | 0.79 | 78.41123 | 285 | NA | NA | NA | Non-antimicrobial | 1EB6; Deuterolysin from Aspergillus oryzae; 2.506e-06 | NA | A0A5N5DA29; Lysine-specific metallo-endopeptidase domain-containing protein; Lasiodiplodia theobromae; 2.919e-17 | A0A4Q4TCS7; Lysine-specific metallo-endopeptidase domain-containing protein; Monosporascus sp. GIB2; 1.482e-15 |
| XANPAGTX0501_010449-T1 | cl32 | Mettalopeptidase | Upregulated in lichen | 0.87 | 89.49591 | 357 | IPR001384 Peptidase M35, deuterolysin;IPR024079 Metallopeptidase, catalytic domain superfamily;IPR029463 Lysine-specific metallo-endopeptidase | NA | M35 | Non-antimicrobial | 1EB6; Deuterolysin from Aspergillus oryzae; 3.4e-21 | 2X3B; AsaP1 inactive mutant E294A, an extracellular toxic zinc metalloendopeptidase; 3.408e-14 | A0A4S9VFN0; Neutral protease 2 (EC 3.4.24.39) (Deuterolysin); Aureobasidium pullulans (Black yeast) (Pullularia pullulans); 2.265e-44 | A0A1V1TI33; Neutral protease 2 (EC 3.4.24.39) (Deuterolysin); Xylariales sp. No.14919; 7.616e-37 |
| XANPAGTX0501_002229-T1 | cl33 | Vacuolar protein sorting-associated protein 62 | Non-DGE | 0.86 | 89.77827 | 346 | IPR009291 Vacuolar protein sorting-associated protein 62 | NA | NA | Non-antimicrobial | NA | NA | A0A5M8PH73; Vacuolar sorting-associated 62; Lasallia pustulata; 3.854e-49 | A0A1W5D5Z6; Vacuolar protein sorting-associated protein 62; Lasallia pustulata; 1.931e-45 |
| XANPAGTX0501_005009-T1 | cl33 | Vacuolar protein sorting-associated protein 62 | Non-DGE | 0.85 | 84.48363 | 386 | IPR009291 Vacuolar protein sorting-associated protein 62 | NA | NA | Non-antimicrobial | NA | NA | A0A4V4I671; Vacuolar protein sorting-associated protein 62; Aureobasidium pullulans (Black yeast) (Pullularia pullulans); 1.132e-47 | A0A6A6GR50; Vacuolar protein sorting-associated protein 62; Elsinoe ampelina; 1.649e-45 |
| XANPAGTX0501_000719-T1 | cl34 | SnoaL | Non-DGE | 0.8 | 83.81541 | 329 | NA | NA | NA | Non-antimicrobial | 7VX2; Crystal Structure of the Y53F/N55A/I80F/L114V/I116V mutant of LEH; 4.872e-06 | 4R9K; Structure of thermostable eightfold mutant of limonene epoxide hydrolase from Rhodococcus erythropolis; 2.03e-05 | A0A6A6BEJ4; SnoaL-like domain-containing protein; Aplosporella prunicola CBS 121167; 1.804e-34 | A0A6G1LCS3; Uncharacterized protein; Teratosphaeria nubilosa; 4.942e-33 |
| XANPAGTX0501_001941-T1 | cl34 | SnoaL | Non-DGE | 0.85 | 90.60792 | 293 | NA | NA | NA | Non-antimicrobial | 3D9R; Crystal structure of ketosteroid isomerase-like protein (YP_049581.1) from ERWINIA CAROTOVORA ATROSEPTICA SCRI1043 at 2.40 A resolution; 0.0004432 | NA | A0A139HMR0; Uncharacterized protein; Pseudocercospora eumusae; 7.208e-33 | M3CZZ1; Uncharacterized protein; Sphaerulina musiva (strain SO2202) (Poplar stem canker fungus) (Septoria musiva); 4.734e-32 |
| XANPAGTX0501_003378-T1 | cl34 | SnoaL | Non-DGE | 0.77 | 81.93318 | 192 | IPR032710 NTF2-like domain superfamily;IPR037401 SnoaL-like domain | NA | NA | Non-antimicrobial | 4L8O; Crystal structure of a bile-acid 7-alpha dehydratase (CLOHYLEM_06634) from Clostridium hylemonae DSM 15053 at 2.20 A resolution; 2.427e-08 | 4STD; HIGH RESOLUTION STRUCTURES OF SCYTALONE DEHYDRATASE-INHIBITOR COMPLEXES CRYSTALLIZED AT PHYSIOLOGICAL PH; 9.329e-07 | A0A2E9SS76; SnoaL-like domain-containing protein; Spongiibacter sp; 8.302e-09 | A0A7H8RCZ4; SnoaL-like domain-containing protein; Talaromyces rugulosus; 9.321e-09 |
| XANPAGTX0501_004515-T1 | cl34 | SnoaL | Upregulated in lichen | 0.76 | 84.68684 | 190 | IPR032710 NTF2-like domain superfamily;IPR037401 SnoaL-like domain | NA | NA | Non-antimicrobial | 4LEH; Crystal structure of a bile-acid 7-alpha dehydratase (CLOSCI_03134) from Clostridium scindens ATCC 35704 at 2.90 A resolution; 2.685e-09 | 3S5C; Crystal Structure of a Hexachlorocyclohexane dehydrochlorinase (LinA) Type2; 7.372e-09 | A0A0N1H2U8; SnoaL-like domain-containing protein; Phialophora attinorum; 1.719e-10 | A0A364NA13; Ethyl tert-butyl ether degradation protein; Stemphylium lycopersici; 2.935e-10 |
| XANPAGTX0501_002728-T1 | cl35 | Annotations do not match | Non-DGE | 0.72 | 76.14354 | 223 | IPR010895 CHRD | NA | NA | Non-antimicrobial | NA | NA | A0A3M7JBK9; CHRD domain-containing protein; Hortaea werneckii; 2.265e-20 | A0A5N6KY16; CHRD domain-containing protein; Carpinus fangiana; 6.646e-20 |
| XANPAGTX0501_005716-T1 | cl35 | Annotations do not match | Non-DGE | 0.62 | 78.42504 | 272 | IPR001424 Superoxide dismutase, copper/zinc binding domain;IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily | NA | NA | Non-antimicrobial | 5CU9; CANDIDA ALBICANS SUPEROXIDE DISMUTASE 5 (SOD5), APO; 2.352e-15 | 5KBL; Candida Albicans Superoxide Dismutase 5 (SOD5), E110Q Mutant; 4.187e-15 | A0A0J8TY34; Cytosolic Cu/Zn superoxide dismutase; Coccidioides immitis RMSCC 3703; 5.351e-21 | H6BU51; Superoxide dismutase; Exophiala dermatitidis (strain ATCC 34100 / CBS 525.76 / NIH/UT8656) (Black yeast) (Wangiella dermatitidis); 5.351e-21 |
| XANPAGTX0501_001455-T1 | cl36 | SUN family | Upregulated in lichen | 0.72 | 75.69017 | 461 | IPR005556 SUN family | GH132 | NA | Antimicrobial | NA | NA | A0A093XL89; SUN domain-containing protein; Pseudogymnoascus sp. VKM F-3808; 1.105e-38 | A0A094DHB8; SUN domain-containing protein; Pseudogymnoascus sp. VKM F-4516 (FW-969); 1.365e-38 |
| XANPAGTX0501_007482-T1 | cl36 | SUN family | Upregulated in culture | 0.56 | 65.13208 | 534 | IPR005556 SUN family | GH132 | NA | Non-antimicrobial | NA | NA | A0A370Q0T6; SUN-domain-containing protein; Aspergillus phoenicis ATCC 13157; 1.325e-47 | A0A1L9UP51; SUN domain-containing protein; Aspergillus brasiliensis (strain CBS 101740 / IMI 381727 / IBT 21946); 3.928e-47 |
| XANPAGTX0501_004065-T1 | cl37 | thaumatin-like | Upregulated in lichen | 0.55 | 65.60249 | 249 | NA | NA | NA | Antimicrobial | NA | NA | NA | NA |
| XANPAGTX0501_004980-T1 | cl37 | thaumatin-like | Non-DGE | 0.78 | 81.87807 | 238 | NA | NA | NA | Non-antimicrobial | 3ZS3; High resolution structure of Mal d 2, the thaumatin like food allergen from apple; 2.839e-07 | NA | A0A1Y1HSG8; Pathogenesis-related thaumatin superfamily protein; Klebsormidium nitens (Green alga) (Ulothrix nitens); 1.569e-07 | A0A4S8ZVY4; Uncharacterized protein; Aureobasidium pullulans (Black yeast) (Pullularia pullulans); 4.391e-07 |
| XANPAGTX0501_000203-T1 | cl38 | thaumatin-like | Non-DGE | 0.79 | 80.85749 | 407 | IPR001938 Thaumatin family;IPR037176 Osmotin/thaumatin-like superfamily | GH152 | NA | Antimicrobial | 1PCV; Crystal structure of osmotin, a plant antifungal protein; 1.711e-20 | 1AUN; PATHOGENESIS-RELATED PROTEIN 5D FROM NICOTIANA TABACUM; 3.375e-20 | A0A0D2GDB4; Osmotin, thaumatin-like protein; Phialophora macrospora; 4.591e-50 | U1GGB9; Peptidase A1 domain-containing protein; Endocarpon pusillum (strain Z07020 / HMAS-L-300199) (Lichen-forming fungus); 5.019e-48 |
| XANPAGTX0501_001160-T1 | cl38 | thaumatin-like | Non-DGE | 0.53 | 59.19148 | 379 | IPR037176 Osmotin/thaumatin-like superfamily | NA | NA | Below pLDDT threshold | 3ZS3; High resolution structure of Mal d 2, the thaumatin like food allergen from apple; 1.142e-06 | 7P23; Thaumatin-like protein of Puccinia graminis; 1.527e-06 | A0A2V4ZJ14; deleted; ; 1.985e-09 | F8C8J9; Lipoprotein; Myxococcus fulvus (strain ATCC BAA-855 / HW-1); 2.362e-09 |
| XANPAGTX0501_001856-T1 | cl38 | thaumatin-like | Upregulated in lichen | 0.75 | 76.44470 | 279 | IPR037176 Osmotin/thaumatin-like superfamily | NA | NA | Antimicrobial | 7P22; Thaumatin-like protein of Amycolatopsis rifamycinica; 1.236e-09 | 2AHN; High resolution structure of a cherry allergen Pru av 2; 3.103e-08 | J3NYP6; Thaumatin family protein; Gaeumannomyces tritici (strain R3-111a-1) (Wheat and barley take-all root rot fungus) (Gaeumannomyces graminis var. tritici); 1.449e-23 | A0A1L7XJV4; Uncharacterized protein; Phialocephala subalpina; 6.443e-23 |
| XANPAGTX0501_006050-T1 | cl38 | thaumatin-like | Non-DGE | 0.78 | 82.52902 | 245 | IPR037176 Osmotin/thaumatin-like superfamily | NA | NA | Non-antimicrobial | 3ZS3; High resolution structure of Mal d 2, the thaumatin like food allergen from apple; 1.157e-10 | 2AHN; High resolution structure of a cherry allergen Pru av 2; 1.128e-09 | A0A0C3GRS3; Thaumatin-like protein; Oidiodendron maius (strain Zn); 1.089e-23 | A0A1L7XJV4; Uncharacterized protein; Phialocephala subalpina; 5.673e-23 |
| XANPAGTX0501_004102-T1 | cl39 | PIR domain | Non-DGE | 0.55 | 59.65142 | 295 | IPR000420 Yeast PIR protein repeat | NA | NA | Below pLDDT threshold | NA | NA | A0A4U0Y4K5; Cell wall protein PhiA; Friedmanniomyces simplex; 2.054e-16 | W2S867; Uncharacterized protein; Cyphellophora europaea CBS 101466; 5.37e-16 |
| XANPAGTX0501_009124-T1 | cl39 | PIR domain | Upregulated in culture | 0.56 | 65.86180 | 272 | NA | NA | NA | Non-antimicrobial | NA | NA | A0A0M8N8D4; Cell wall mannoprotein CIS3; Escovopsis weberi; 1.477e-11 | A0A151GVE1; U1-C C2H2-type zinc finger domain-containing protein; Drechmeria coniospora; 3.936e-11 |
| XANPAGTX0501_005564-T1 | cl40 | No annotation | Non-DGE | 0.83 | 89.79662 | 210 | NA | NA | NA | Non-antimicrobial | NA | NA | A0A1F5L410; IgE-binding protein; Penicillium arizonense; 2.325e-16 | A0A101MIG8; IgE-binding protein; Penicillium freii; 1.39e-15 |
| XANPAGTX0501_008990-T1 | cl40 | No annotation | Upregulated in lichen | 0.72 | 76.45494 | 249 | NA | NA | NA | Antimicrobial | NA | NA | A0A679NV77; deleted; ; 1.834e-09 | A0A2J6PP26; WW domain-containing protein; Hyaloscypha hepaticicola; 3.444e-09 |
| XANPAGTX0501_000656-T1 | cl41 | Ricin B-like lectin | Upregulated in lichen | 0.76 | 79.99352 | 196 | IPR035992 Ricin B-like lectins | NA | NA | Non-antimicrobial | 8BAD; Tpp80Aa1; 3.84e-07 | 4I4Q; BEL beta-trefoil apo crystal form 3; 7.991e-06 | A0A1Q3M7K9; Ricin B lectin domain-containing protein; Bacteroidales bacterium 45-6; 1.63e-09 | A0A5M8P4M8; Ricin B lectin domain-containing protein; Candidatus Ordinivivax streblomastigis; 7.834e-09 |
| XANPAGTX0501_006283-T1 | cl41 | Ricin B-like lectin | Upregulated in lichen | 0.53 | 56.14573 | 335 | IPR035992 Ricin B-like lectins | NA | NA | Below pLDDT threshold | 3PG0; Crystal structure of designed 3-fold symmetric protein, ThreeFoil; 3.676e-08 | 7ZNX; Crystal structure of cocaprin 1, inhibitor of cysteine and aspartic proteases from Coprinopsis cinerea; 1.846e-07 | A0A1L7XN80; Ricin B lectin domain-containing protein; Phialocephala subalpina; 1.391e-07 | A0A229REW7; Ricin B lectin domain-containing protein; Amycolatopsis alba DSM 44262; 6.621e-07 |
| XANPAGTX0501_010170-T1 | cl41 | Ricin B-like lectin | Upregulated in lichen | 0.75 | 79.09385 | 200 | IPR035992 Ricin B-like lectins | NA | NA | Non-antimicrobial | 2X2S; Crystal structure of Sclerotinia sclerotiorum agglutinin SSA; 1.416e-10 | 6YH0; Marasmius oreades agglutinin (MOA) in complex with the truncated PVPRAHS synthetic substrate; 4.127e-09 | A0A5M8P4M8; Ricin B lectin domain-containing protein; Candidatus Ordinivivax streblomastigis; 2.28e-10 | A0A1Q3M7K9; Ricin B lectin domain-containing protein; Bacteroidales bacterium 45-6; 1.077e-09 |
| XANPAGTX0501_009887-T1 | cl42 | Match to Trichoderma effector | Upregulated in lichen | 0.77 | 88.68807 | 145 | NA | NA | NA | Non-antimicrobial | 7CWJ; Root induced Secreted protein Tsp1 from Biocontrol fungi Trichoderma virens; 1.474e-12 | NA | A0A6A6PH20; Small secreted protein; Neohortaea acidophila; 2.751e-14 | R8B8V1; Putative small secreted protein; Phaeoacremonium minimum (strain UCR-PA7) (Esca disease fungus) (Togninia minima); 3.369e-13 |
| XANPAGTX0501_005096-T1 | cl43 | GH43 | Non-DGE | 0.91 | 94.66982 | 325 | IPR006710 Glycoside hydrolase, family 43;IPR016840 Glycoside hydrolase, family 43, endo-1, 5-alpha-L-arabinosidase;IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily | GH43 | NA | Antimicrobial | 1UV4; Native Bacillus subtilis Arabinanase Arb43A; 1.013e-22 | 6B7K; GH43 Endo-Arabinanase from Bacillus licheniformis; 1.088e-21 | A0A4S9FM27; Arabinan endo-1,5-alpha-L-arabinosidase (EC 3.2.1.99); Aureobasidium pullulans (Black yeast) (Pullularia pullulans); 1.658e-39 | C6HSE3; Arabinan endo-1,5-alpha-L-arabinosidase (EC 3.2.1.99); Ajellomyces capsulatus (strain H143) (Darling’s disease fungus) (Histoplasma capsulatum); 1.135e-36 |
| XANPAGTX0501_010132-T1 | cl43 | GH43 | Upregulated in culture | 0.89 | 93.56190 | 331 | IPR006710 Glycoside hydrolase, family 43;IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily | GH43 | NA | Non-antimicrobial | 4QQS; Crystal structure of a thermostable family-43 glycoside hydrolase; 4.459e-20 | 3QZ4; Crystal structure of an Endo-1,4-beta-xylanase D (BT_3675) from Bacteroides thetaiotaomicron VPI-5482 at 1.74 A resolution; 2.127e-18 | A0A178BRK4; deleted; ; 5.515e-37 | A0A0D2GG01; Glycoside hydrolase family 43 protein; Fonsecaea pedrosoi CBS 271.37; 2.227e-36 |
| XANPAGTX0501_004076-T1 | cl44 | Six-bladed beta-propeller, TolB-like | Non-DGE | 0.91 | 93.69540 | 415 | IPR011042 Six-bladed beta-propeller, TolB-like;IPR017996 Major royal jelly protein/protein yellow | NA | NA | Non-antimicrobial | 2QE8; Crystal structure of a putative hydrolase (ava_4197) from anabaena variabilis atcc 29413 at 1.35 A resolution; 2.27e-25 | 5I5M; Shewanella denitrificans nitrous oxide reductase, Ca2+-reconstituted form; 5.254e-08 | A0A4U0XN52; Yippee domain-containing protein; Friedmanniomyces simplex; 1.999e-61 | A0A074X049; Major royal jelly protein; Aureobasidium melanogenum CBS 110374; 6.732e-60 |
| XANPAGTX0501_009462-T1 | cl44 | Six-bladed beta-propeller, TolB-like | Non-DGE | 0.83 | 86.40844 | 482 | IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase;IPR011042 Six-bladed beta-propeller, TolB-like | AA12 | NA | Non-antimicrobial | 6I1Q; Iodide structure of Trichoderma reesei Carbohydrate-Active Enzymes Family AA12; 1.964e-55 | 6I1T; Calcium structure of Trichoderma reesei Carbohydrate-Active Enzymes Family AA12; 6.186e-55 | A0A6A6Y8K3; Soluble quino protein glucose dehydrogenase; Mytilinidion resinicola; 2.263e-64 | R7YHI9; Glucose/Sorbosone dehydrogenase domain-containing protein; Coniosporium apollinis (strain CBS 100218) (Rock-inhabiting black yeast); 9.216e-62 |
| XANPAGTX0501_002723-T1 | cl45 | Arylsulfotransferase-like | Upregulated in culture | 0.86 | 86.38564 | 548 | IPR039535 Arylsulfotransferase-like | NA | NA | Antimicrobial | NA | NA | A0A4U0V102; ASST-domain-containing protein; Friedmanniomyces endolithicus; 2.083e-47 | A0A6G1KWJ1; ASST-domain-containing protein; Teratosphaeria nubilosa; 1.765e-45 |
| XANPAGTX0501_005133-T1 | cl45 | Arylsulfotransferase-like | Upregulated in lichen | 0.89 | 90.85668 | 394 | IPR039535 Arylsulfotransferase-like | NA | NA | Non-antimicrobial | 2DSO; Crystal structure of D138N mutant of Drp35, a 35kDa drug responsive protein from Staphylococcus aureus; 0.0006019 | NA | A0A6A6Z1L7; ASST-domain-containing protein; Mytilinidion resinicola; 2.017e-37 | A0A3M0VWU9; ASST-domain-containing protein; Chaetothyriales sp. CBS 134920; 1.006e-36 |
| XANPAGTX0501_004346-T1 | cl46 | Annotations do not match | Upregulated in lichen | 0.92 | 94.10081 | 445 | IPR027589 Choice-of-anchor B domain | NA | NA | Non-antimicrobial | 3F3P; Crystal structure of the nucleoporin pair Nup85-Seh1, space group P21212; 1.951e-06 | 3F3F; Crystal structure of the nucleoporin pair Nup85-Seh1, space group P21; 1.039e-05 | A0A094EZH8; Regulatory P domain-containing protein; Pseudogymnoascus sp. VKM F-4518 (FW-2643); 1.181e-71 | A0A094H9D5; Phospholipase/carboxylesterase/thioesterase domain-containing protein; Pseudogymnoascus sp. VKM F-4519 (FW-2642); 2.142e-70 |
| XANPAGTX0501_007937-T1 | cl46 | Annotations do not match | Upregulated in culture | 0.89 | 91.92003 | 398 | IPR011044 Quinoprotein amine dehydrogenase, beta chain-like;IPR015943 WD40/YVTN repeat-like-containing domain superfamily | NA | NA | Antimicrobial | 5B4X; Crystal structure of the ApoER2 ectodomain in complex with the Reelin R56 fragment; 6.968e-07 | 3P5B; The structure of the LDLR/PCSK9 complex reveals the receptor in an extended conformation; 4.433e-06 | S8BLJ6; SMP-30/Gluconolactonase/LRE-like region domain-containing protein; Dactylellina haptotyla (strain CBS 200.50) (Nematode-trapping fungus) (Monacrosporium haptotylum); 4.073e-38 | A0A136IT31; 3-carboxymuconate cyclase; Microdochium bolleyi; 1.672e-37 |
| XANPAGTX0501_010580-T1 | cl46 | Annotations do not match | Upregulated in lichen | 0.9 | 91.04026 | 427 | IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily;IPR015943 WD40/YVTN repeat-like-containing domain superfamily;IPR019405 Lactonase, 7-bladed beta propeller | NA | NA | Antimicrobial | 3FGB; Crystal structure of the Q89ZH8_BACTN protein from Bacteroides thetaiotaomicron. Northeast Structural Genomics Consortium target BtR289b.; 9.951e-19 | 3SCY; Crystal structure of a putative 6-phosphogluconolactonase (BF1038) from Bacteroides fragilis NCTC 9343 at 1.50 A resolution; 1.206e-18 | A0A2V1E0R6; Putative isomerase YbhE; Periconia macrospinosa; 3.423e-30 | S3DGB5; Nitrous oxide reductase, N-terminal; Glarea lozoyensis (strain ATCC 20868 / MF5171); 2.445e-29 |
| XANPAGTX0501_002120-T1 | cl47 | Germins cupins | Non-DGE | 0.68 | 78.28887 | 291 | IPR001929 Germin;IPR006045 Cupin 1;IPR011051 RmlC-like cupin domain superfamily;IPR014710 RmlC-like jelly roll fold;IPR019780 Germin, manganese binding site | NA | NA | Non-antimicrobial | 6ORM; Crystal Structure of Peruvianin-I (Cysteine peptidase from Thevetia peruviana latex); 1e-12 | 2D5H; Crystal Structure of Recombinant Soybean Proglycinin A3B4 subunit, its Comparison with Mature Glycinin A3B4 subunit, Responsible for Hexamer Assembly; 6.395e-11 | A0A3M6X7P0; Cupin type-1 domain-containing protein; Hortaea werneckii; 6.228e-33 | A0A6A6TUZ1; Spherulin-1A; Microthyrium microscopicum; 9.708e-31 |
| XANPAGTX0501_004938-T1 | cl47 | Germins cupins | Non-DGE | 0.87 | 92.12722 | 418 | IPR006045 Cupin 1;IPR011051 RmlC-like cupin domain superfamily;IPR014710 RmlC-like jelly roll fold;IPR017774 Bicupin, oxalate decarboxylase/oxidase | NA | NA | Non-antimicrobial | 1L3J; Crystal Structure of Oxalate Decarboxylase Formate Complex; 9.185e-51 | 2UY9; E162A mutant of Bacillus subtilis Oxalate Decarboxylase OxdC; 1.793e-50 | A0A3M7N675; Cupin type-1 domain-containing protein; Chaetothyriales sp. CBS 135597; 1.726e-62 | V9DGY0; Cupin type-1 domain-containing protein; Cladophialophora carrionii CBS 160.54; 3.916e-61 |
| XANPAGTX0501_005784-T1 | cl48 | No annotation | Non-DGE | 0.78 | 88.24251 | 187 | NA | NA | NA | Antimicrobial | NA | NA | U1GM31; Small secreted protein; Endocarpon pusillum (strain Z07020 / HMAS-L-300199) (Lichen-forming fungus); 1.646e-20 | A0A165BYR1; Small secreted protein; Exidia glandulosa HHB12029; 2.307e-18 |
| XANPAGTX0501_007256-T1 | cl48 | No annotation | Non-DGE | 0.82 | 91.39403 | 176 | NA | NA | NA | Non-antimicrobial | NA | NA | A0A177CNP0; Uncharacterized protein; Paraphaeosphaeria sporulosa; 5.474e-19 | A0A1Y2E8A8; Small secreted protein; Pseudomassariella vexata; 1.785e-18 |
| XANPAGTX0501_010209-T1 | cl48 | No annotation | Non-DGE | 0.82 | 91.39403 | 176 | NA | NA | NA | Non-antimicrobial | NA | NA | A0A177CNP0; Uncharacterized protein; Paraphaeosphaeria sporulosa; 5.474e-19 | A0A1Y2E8A8; Small secreted protein; Pseudomassariella vexata; 1.785e-18 |
| XANPAGTX0501_000458-T1 | cl49 | GH16 | Non-DGE | 0.71 | 78.33200 | 400 | IPR000757 Glycoside hydrolase family 16;IPR013320 Concanavalin A-like lectin/glucanase domain superfamily | GH16 | NA | Non-antimicrobial | 3WDV; The complex structure of PtLic16A with cellotetraose; 5.664e-38 | 3WDW; The apo-form structure of E113A from Paecilomyces thermophila; 9.174e-37 | A0A0D1ZG35; GH16 domain-containing protein; Exophiala mesophila (Black yeast); 2.958e-40 | A0A3M7MV44; GH16 domain-containing protein; Chaetothyriales sp. CBS 132003; 4.368e-40 |
| XANPAGTX0501_000471-T1 | cl49 | GH16 | Non-DGE | 0.82 | 84.78436 | 376 | IPR000757 Glycoside hydrolase family 16;IPR013320 Concanavalin A-like lectin/glucanase domain superfamily | GH16 | NA | Antimicrobial | 1U0A; Crystal structure of the engineered beta-1,3-1,4-endoglucanase H(A16-M) in complex with beta-glucan tetrasaccharide; 3.812e-14 | 1GLH; CATION BINDING TO A BACILLUS (1,3-1,4)-BETA-GLUCANASE. GEOMETRY, AFFINITY AND EFFECT ON PROTEIN STABILITY; 9.243e-14 | A0A6A6B611; Glycoside hydrolase family 16 protein; Aplosporella prunicola CBS 121167; 4.021e-41 | A0A4Q4MZN5; GH16 domain-containing protein; Alternaria alternata (Alternaria rot fungus) (Torula alternata); 1.518e-40 |
| XANPAGTX0501_001066-T1 | cl49 | GH16 | Non-DGE | 0.66 | 74.05068 | 444 | IPR000757 Glycoside hydrolase family 16;IPR013320 Concanavalin A-like lectin/glucanase domain superfamily | GH16 | NA | Antimicrobial | 3WDW; The apo-form structure of E113A from Paecilomyces thermophila; 2.475e-36 | 3WDV; The complex structure of PtLic16A with cellotetraose; 8.828e-36 | A0A0D2CUR1; GH16 domain-containing protein; Exophiala xenobiotica; 3.298e-38 | A0A6G0UNG1; GH16 domain-containing protein; Halicephalobus sp. NKZ332; 6.766e-38 |
| XANPAGTX0501_001263-T1 | cl49 | GH16 | Non-DGE | 0.8 | 82.89324 | 364 | IPR000757 Glycoside hydrolase family 16;IPR013320 Concanavalin A-like lectin/glucanase domain superfamily | GH16 | NA | Non-antimicrobial | 1U0A; Crystal structure of the engineered beta-1,3-1,4-endoglucanase H(A16-M) in complex with beta-glucan tetrasaccharide; 1.155e-11 | 1GBG; BACILLUS LICHENIFORMIS BETA-GLUCANASE; 1.996e-11 | A0A6A6V9K5; Glycoside hydrolase family 16 protein; Sporormia fimetaria CBS 119925; 6.502e-34 | A0A1L9Q3G8; GH16 domain-containing protein; Aspergillus versicolor CBS 583.65; 2.168e-33 |
| XANPAGTX0501_004812-T1 | cl49 | GH16 | Non-DGE | 0.61 | 66.67060 | 464 | IPR000757 Glycoside hydrolase family 16;IPR013320 Concanavalin A-like lectin/glucanase domain superfamily | GH16 | NA | Non-antimicrobial | 6IBW; Crh5 transglycosylase in complex with NAG; 1.481e-28 | 6IBW; Crh5 transglycosylase in complex with NAG; 3.832e-28 | A0A4U0WMI9; GH16 domain-containing protein; Cryomyces minteri; 4.233e-39 | A0A1X7RWD6; GH16 domain-containing protein; Zymoseptoria tritici ST99CH_3D7; 5.176e-37 |
| XANPAGTX0501_005822-T1 | cl49 | GH16 | Non-DGE | 0.77 | 80.21573 | 454 | IPR000757 Glycoside hydrolase family 16;IPR013320 Concanavalin A-like lectin/glucanase domain superfamily;IPR017168 Glycoside hydrolase, family 16, CRH1, predicted;IPR018371 Chitin-binding, type 1, conserved site | GH16 | NA | Antimicrobial | 6IBW; Crh5 transglycosylase in complex with NAG; 2.336e-20 | 6IBU; Apo Crh5 transglycosylase; 6.365e-20 | A0A3M2SVX8; Glycosidase (EC 3.2.-.-); Aspergillus sp. HF37; 4.506e-46 | A0A167FBP7; Glycosidase (EC 3.2.-.-); Sugiyamaella lignohabitans; 2.983e-42 |
| XANPAGTX0501_009699-T1 | cl49 | GH16 | Upregulated in lichen | 0.64 | 77.79897 | 513 | IPR000757 Glycoside hydrolase family 16;IPR001002 Chitin-binding, type 1;IPR008264 Beta-glucanase;IPR013320 Concanavalin A-like lectin/glucanase domain superfamily;IPR036861 Endochitinase-like superfamily | GH16 | NA | Antimicrobial | 1U0A; Crystal structure of the engineered beta-1,3-1,4-endoglucanase H(A16-M) in complex with beta-glucan tetrasaccharide; 8.474e-16 | 1GLH; CATION BINDING TO A BACILLUS (1,3-1,4)-BETA-GLUCANASE. GEOMETRY, AFFINITY AND EFFECT ON PROTEIN STABILITY; 4.226e-15 | M3C4X1; Glycoside hydrolase family 16 protein; Sphaerulina musiva (strain SO2202) (Poplar stem canker fungus) (Septoria musiva); 3.925e-31 | A0A1V8TT27; GH16 domain-containing protein; Rachicladosporium antarcticum; 9.526e-31 |
| XANPAGTX0501_010345-T1 | cl49 | GH16 | Non-DGE | 0.82 | 86.19722 | 263 | IPR000757 Glycoside hydrolase family 16;IPR013320 Concanavalin A-like lectin/glucanase domain superfamily | GH16 | NA | Non-antimicrobial | 1GBG; BACILLUS LICHENIFORMIS BETA-GLUCANASE; 2.032e-11 | 1U0A; Crystal structure of the engineered beta-1,3-1,4-endoglucanase H(A16-M) in complex with beta-glucan tetrasaccharide; 4.443e-11 | M3B913; Glycoside hydrolase family 16 protein; Pseudocercospora fijiensis (strain CIRAD86) (Black leaf streak disease fungus) (Mycosphaerella fijiensis); 2.356e-19 | A0A1V8TT27; GH16 domain-containing protein; Rachicladosporium antarcticum; 8.68e-19 |
| XANPAGTX0501_005095-T1 | cl50 | GH12 | Non-DGE | 0.85 | 90.88338 | 269 | IPR002594 Glycoside hydrolase family 12;IPR013319 Glycoside hydrolase family 11/12;IPR013320 Concanavalin A-like lectin/glucanase domain superfamily | GH12 | NA | Antimicrobial | 4H7M; The X-ray Crystal Structure of the Trichoderma harzianum Endoglucanase 3 from family GH12; 2.235e-18 | 1OA2; Comparison of Family 12 Glycoside Hydrolases and Recruited Substitutions Important for Thermal Stability; 3.044e-18 | A0A1L7WVT4; Related to endoglucanase I; Phialocephala subalpina; 5.356e-37 | A0A318ZLM3; xyloglucan-specific endo-beta-1,4-glucanase (EC 3.2.1.151) (Xyloglucanase A) (Xyloglucanendohydrolase A); Aspergillus saccharolyticus JOP 1030-1; 3.788e-36 |
| XANPAGTX0501_005389-T1 | cl50 | GH12 | Non-DGE | 0.86 | 91.83622 | 249 | IPR002594 Glycoside hydrolase family 12;IPR013319 Glycoside hydrolase family 11/12;IPR013320 Concanavalin A-like lectin/glucanase domain superfamily | GH12 | NA | Antimicrobial | 3VLB; Crystal structure of xeg-edgp; 9.282e-29 | 4NPR; Crystal Structure of the Family 12 Xyloglucanase from Aspergillus niveus; 1.27e-28 | A0A4Q4RW40; Xyloglucan-specific endo-beta-1,4-glucanase A; Alternaria arborescens; 2.502e-33 | A0A7U2EXK0; Uncharacterized protein; Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Parastagonospora nodorum); 1.885e-26 |
| XANPAGTX0501_005664-T1 | cl51 | Galactose-binding domain | Upregulated in culture | 0.52 | 63.25380 | 276 | NA | GH128 | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_006702-T1 | cl51 | Galactose-binding domain | Non-DGE | 0.55 | 66.47848 | 297 | IPR008979 Galactose-binding-like domain superfamily | NA | NA | Antimicrobial | 5W6H; Crystal structure of Bacteriophage CBA120 tailspike protein 4 enzymatically active domain (TSP4dN, orf213); 1.397e-07 | 2XOM; Atomic resolution structure of TmCBM61 in complex with beta-1,4- galactotriose; 1.331e-06 | W0J3J6; Carbohydrate-binding protein CenC; Opitutaceae bacterium TAV5; 1.779e-07 | A0A1V8TMC2; Uncharacterized protein; Rachicladosporium sp. CCFEE 5018; 2.954e-07 |
| XANPAGTX0501_006869-T1 | cl51 | Galactose-binding domain | Upregulated in culture | 0.63 | 77.22822 | 270 | IPR008979 Galactose-binding-like domain superfamily | GH128 | NA | Antimicrobial | 4D0Q; Hyaluronan Binding Module of the Streptococcal Pneumoniae Hyaluronate Lyase; 5.281e-08 | 5X7S; Crystal structure of Paenibacillus sp. 598K alpha-1,6-glucosyltransferase, terbium derivative; 5.515e-06 | L2G4D3; Uncharacterized protein; Colletotrichum fructicola (strain Nara gc5) (Anthracnose fungus) (Colletotrichum gloeosporioides (strain Nara gc5)); 2.695e-19 | A0A1V1TIS2; CBM-cenC domain-containing protein; Xylariales sp. No.14919; 3.906e-16 |
| XANPAGTX0501_007616-T1 | cl51 | Galactose-binding domain | Non-DGE | 0.59 | 68.60583 | 290 | IPR008979 Galactose-binding-like domain superfamily | NA | NA | Non-antimicrobial | 2Y6H; X-2 L110F CBM4-2 Carbohydrate Binding Module from a Thermostable Rhodothermus marinus Xylanase; 3.124e-09 | 3OEB; Crystal structure of the Q121E mutant of C.polysaccharolyticus CBM16-1 bound to mannopentaose; 1.295e-07 | A0A5R9GPG3; Dockerin domain-containing protein; Paenibacillus antri; 1.147e-08 | A0A0N8H727; Uncharacterized protein; Neonectria ditissima; 1.072e-07 |
| XANPAGTX0501_008830-T1 | cl51 | Galactose-binding domain | Non-DGE | 0.54 | 68.70455 | 299 | IPR008979 Galactose-binding-like domain superfamily | NA | NA | Antimicrobial | 8HHV; endo-alpha-D-arabinanase EndoMA1 from Microbacterium arabinogalactanolyticum; 3.315e-08 | 8IC1; endo-alpha-D-arabinanase EndoMA1 D51N mutant from Microbacterium arabinogalactanolyticum in complex with arabinooligosaccharides; 3.722e-08 | A0A1W9VTK2; Peptidase M14 carboxypeptidase A domain-containing protein; Candidatus Cloacimonetes bacterium 4572_65; 1.961e-06 | A0A4R6MXZ4; deleted; ; 4.949e-06 |
| XANPAGTX0501_009317-T1 | cl51 | Galactose-binding domain | Upregulated in lichen | 0.58 | 66.13799 | 294 | IPR008979 Galactose-binding-like domain superfamily | NA | NA | Non-antimicrobial | 2XOM; Atomic resolution structure of TmCBM61 in complex with beta-1,4- galactotriose; 1.095e-08 | 5X7S; Crystal structure of Paenibacillus sp. 598K alpha-1,6-glucosyltransferase, terbium derivative; 3.285e-05 | A0A5J5ERX4; CBM-cenC domain-containing protein; Sphaerosporella brunnea; 3.593e-11 | A0A6A6YR49; Apple domain-containing protein; Mytilinidion resinicola; 2.892e-07 |
| XANPAGTX0501_010474-T1 | cl51 | Galactose-binding domain | Upregulated in culture | 0.79 | 84.95214 | 201 | IPR008979 Galactose-binding-like domain superfamily | NA | NA | Non-antimicrobial | 2ZEZ; Family 16 Carbohydrate Binding Module-2; 4.183e-06 | 2WZE; High resolution crystallographic structure of the Clostridium thermocellum N-terminal endo-1,4-beta-D-xylanase 10B (Xyn10B) CBM22-1- GH10 modules complexed with xylohexaose; 0.0001278 | A0A3M1RXR0; Choice-of-anchor C family protein; Gammaproteobacteria bacterium; 4.499e-07 | A0A7S6M730; Tail specific protease domain-containing protein; Planctomycetia bacterium; 6.139e-07 |
| XANPAGTX0501_010647-T1 | cl51 | Galactose-binding domain | Non-DGE | 0.63 | 72.54673 | 260 | IPR008979 Galactose-binding-like domain superfamily | GH128 | NA | Antimicrobial | 5W6H; Crystal structure of Bacteriophage CBA120 tailspike protein 4 enzymatically active domain (TSP4dN, orf213); 2.615e-08 | 4D0Q; Hyaluronan Binding Module of the Streptococcal Pneumoniae Hyaluronate Lyase; 5.658e-08 | A0A7C8GXG9; deleted; ; 4.344e-09 | A0A2T5M4Z2; CBM-cenC domain-containing protein; Aspergillus ochraceoroseus IBT 24754; 1.342e-08 |
| XANPAGTX0501_001631-T1 | cl52 | No annotation | Non-DGE | 0.78 | 83.01637 | 226 | NA | NA | NA | Non-antimicrobial | NA | NA | A0A5M8PD82; Uncharacterized protein; Lasallia pustulata; 1.707e-19 | A0A1C1CJ21; Secreted protein; Cladophialophora carrionii; 1.088e-16 |
| XANPAGTX0501_006271-T1 | cl52 | No annotation | Non-DGE | 0.74 | 72.47268 | 224 | NA | NA | NA | Non-antimicrobial | NA | NA | W3WJ19; Uncharacterized protein; Pestalotiopsis fici (strain W106-1 / CGMCC3.15140); 1.207e-11 | W3WUU5; Ubiquitin 3 binding protein But2 C-terminal domain-containing protein; Pestalotiopsis fici (strain W106-1 / CGMCC3.15140); 2.754e-10 |
| XANPAGTX0501_006292-T1 | cl52 | No annotation | Upregulated in lichen | 0.78 | 81.49940 | 215 | NA | NA | NA | Non-antimicrobial | NA | NA | A0A2D3UQP5; Uncharacterized protein; Ramularia collo-cygni; 3.639e-12 | G1XUG8; Uncharacterized protein; Arthrobotrys oligospora (strain ATCC 24927 / CBS 115.81 / DSM 1491) (Nematode-trapping fungus) (Didymozoophaga oligospora); 3.254e-11 |
| XANPAGTX0501_010443-T1 | cl52 | No annotation | Upregulated in lichen | 0.78 | 81.49940 | 215 | NA | NA | NA | Non-antimicrobial | NA | NA | A0A2D3UQP5; Uncharacterized protein; Ramularia collo-cygni; 3.639e-12 | G1XUG8; Uncharacterized protein; Arthrobotrys oligospora (strain ATCC 24927 / CBS 115.81 / DSM 1491) (Nematode-trapping fungus) (Didymozoophaga oligospora); 3.254e-11 |
| XANPAGTX0501_010550-T1 | cl52 | No annotation | Non-DGE | 0.76 | 76.22018 | 221 | NA | NA | NA | Non-antimicrobial | NA | NA | A0A6H0XPF1; Uncharacterized protein; Peltaster fructicola; 2.477e-13 | W3WJ19; Uncharacterized protein; Pestalotiopsis fici (strain W106-1 / CGMCC3.15140); 2.946e-12 |
| XANPAGTX0501_005696-T1 | cl53 | Galactose-binding domain Coagulation factor. different otherwise | Non-DGE | 0.58 | 66.59997 | 308 | IPR000421 Coagulation factor 5/8 C-terminal domain;IPR008979 Galactose-binding-like domain superfamily | AA5, CBM32 | NA | Non-antimicrobial | 2VZ3; bleached galactose oxidase; 3.085e-16 | 2EIB; Crystal Structure of Galactose Oxidase, W290H mutant; 4.113e-16 | W3WLU1; F5/8 type C domain-containing protein; Pestalotiopsis fici (strain W106-1 / CGMCC3.15140); 2.397e-14 | A0A2R4TD26; Arabinogalactan endo-1,4-beta-galactosidase; Streptomyces lunaelactis; 3.01e-13 |
| XANPAGTX0501_007182-T1 | cl53 | Galactose-binding domain Coagulation factor. different otherwise | Upregulated in culture | 0.91 | 91.41861 | 1042 | IPR005195 Glycoside hydrolase, family 65, central catalytic;IPR005196 Glycoside hydrolase, family 65, N-terminal;IPR008928 Six-hairpin glycosidase superfamily;IPR008979 Galactose-binding-like domain superfamily;IPR011013 Galactose mutarotase-like domain superfamily;IPR012341 Six-hairpin glycosidase-like superfamily;IPR037018 Glycoside hydrolase family 65, N-terminal domain superfamily | NA | NA | Antimicrobial | 7FE3; Crystal structure of GH65 alpha-1,2-glucosidase from Flavobacterium johnsoniae; 8.632e-41 | 6W0P; Putative kojibiose phosphorylase from human microbiome; 1.749e-38 | A0A0D2H2P1; alpha,alpha-trehalase (EC 3.2.1.28); Fonsecaea pedrosoi CBS 271.37; 0 | A0A3A2ZJN6; alpha,alpha-trehalase (EC 3.2.1.28); Aspergillus sclerotialis; 0 |
| XANPAGTX0501_008294-T1 | cl53 | Galactose-binding domain Coagulation factor. different otherwise | Upregulated in culture | 0.94 | 95.20532 | 643 | IPR000421 Coagulation factor 5/8 C-terminal domain;IPR006652 Kelch repeat type 1;IPR008979 Galactose-binding-like domain superfamily;IPR011043 Galactose oxidase/kelch, beta-propeller;IPR013783 Immunoglobulin-like fold;IPR014756 Immunoglobulin E-set;IPR015202 Galactose oxidase-like, Early set domain;IPR037293 Galactose oxidase, central domain superfamily | AA5, CBM32 | NA | Non-antimicrobial | 1T2X; Glactose oxidase C383S mutant identified by directed evolution; 3.095e-87 | 6XLS; The 1.80 Angstrom crystal structure of galactose oxidase variant with genetically incorporated F2-Tyr272; 5.263e-87 | A0A7C8KZS6; deleted; ; 2.95e-61 | A0A2T2N4Y8; Galactose oxidase; Corynespora cassiicola Philippines; 8.129e-61 |
| XANPAGTX0501_009936-T1 | cl53 | Galactose-binding domain Coagulation factor. different otherwise | Upregulated in lichen | 0.79 | 86.94823 | 972 | IPR000421 Coagulation factor 5/8 C-terminal domain;IPR006652 Kelch repeat type 1;IPR008979 Galactose-binding-like domain superfamily;IPR011043 Galactose oxidase/kelch, beta-propeller;IPR013783 Immunoglobulin-like fold;IPR014756 Immunoglobulin E-set;IPR015202 Galactose oxidase-like, Early set domain;IPR037293 Galactose oxidase, central domain superfamily | AA5, CBM32 | NA | Antimicrobial | 6STX; Copper oxidase from Colletotrichum graminicola; 4.678e-63 | 6RYX; Copper oxidase from Colletotrichum graminicola; 8.31e-62 | A0A0S6X9K8; Galactose oxidase-like Early set domain-containing protein; Fungal sp. (strain No.11243); 9.183e-73 | A0A2G5HG28; Galactose oxidase; Cercospora beticola (Sugarbeet leaf spot fungus); 6.199e-66 |
| XANPAGTX0501_010688-T1 | cl53 | Galactose-binding domain Coagulation factor. different otherwise | Non-DGE | 0.58 | 66.59997 | 308 | IPR000421 Coagulation factor 5/8 C-terminal domain;IPR008979 Galactose-binding-like domain superfamily | AA5, CBM32 | NA | Non-antimicrobial | 2VZ3; bleached galactose oxidase; 3.085e-16 | 2EIB; Crystal Structure of Galactose Oxidase, W290H mutant; 4.113e-16 | W3WLU1; F5/8 type C domain-containing protein; Pestalotiopsis fici (strain W106-1 / CGMCC3.15140); 2.397e-14 | A0A2R4TD26; Arabinogalactan endo-1,4-beta-galactosidase; Streptomyces lunaelactis; 3.01e-13 |
| XANPAGTX0501_007392-T1 | cl54 | Chloroperoxidase | Non-DGE | 0.87 | 91.03036 | 249 | IPR000028 Chloroperoxidase;IPR036851 Chloroperoxidase-like superfamily | NA | NA | Non-antimicrobial | 7O1X; Unspecific peroxygenase from Hypoxylon sp. EC38 in complex with 1-phenylimidazole; 4.226e-18 | 7ZNW; Artificial Unspecific Peroxygenase expressed in Escherichia coli at 2.09 Angstrom resolution; 1.492e-17 | A0A1Q8S4R8; Putative sterigmatocystin biosynthesis peroxidase stcC 1; Colletotrichum chlorophyti; 8.958e-20 | Q0CS13; Heme haloperoxidase family profile domain-containing protein; Aspergillus terreus (strain NIH 2624 / FGSC A1156); 3.941e-18 |
| XANPAGTX0501_008027-T1 | cl54 | Chloroperoxidase | Upregulated in lichen | 0.69 | 66.39988 | 481 | IPR000028 Chloroperoxidase;IPR036851 Chloroperoxidase-like superfamily | NA | NA | Non-antimicrobial | 7PN7; Evolved unspecific peroxygenase with A77L mutation in complex with palmitoleic acid; 2.227e-08 | 2YP1; Crystallization of a 45 kDa peroxygenase- peroxidase from the mushroom Agrocybe aegerita and structure determination by SAD utilizing only the haem iron; 1.326e-07 | A0A098E104; Chromosome 3, complete genome; Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1) (Wheat head blight fungus) (Fusarium graminearum); 1.377e-36 | A0A366RUC2; deleted; ; 2.739e-34 |
| XANPAGTX0501_000358-T1 | cl55 | FAD linked oxidase | Non-DGE | 0.9 | 92.58079 | 607 | IPR006094 FAD linked oxidase, N-terminal;IPR012951 Berberine/berberine-like;IPR016166 FAD-binding domain, PCMH-type;IPR036318 FAD-binding, type PCMH-like superfamily | AA7 | NA | Non-antimicrobial | 6EO4; Physcomitrella patens BBE-like 1 wild-type; 1.746e-26 | 6EO5; Physcomitrella patens BBE-like 1 variant D396N; 2.213e-26 | A0A093YD50; FAD-binding PCMH-type domain-containing protein; Pseudogymnoascus sp. VKM F-3808; 1.81e-84 | A0A072Q3X7; FAD-binding PCMH-type domain-containing protein; Exophiala aquamarina CBS 119918; 3.119e-83 |
| XANPAGTX0501_003196-T1 | cl55 | FAD linked oxidase | Non-DGE | 0.9 | 92.25110 | 590 | IPR006094 FAD linked oxidase, N-terminal;IPR012951 Berberine/berberine-like;IPR016166 FAD-binding domain, PCMH-type;IPR036318 FAD-binding, type PCMH-like superfamily | NA | NA | Antimicrobial | 6F73; Crystal structure of VAO-type flavoprotein MtVAO615 at pH 5.0 from Myceliophthora thermophila C1; 1.182e-59 | 6F74; Crystal structure of VAO-type flavoprotein MtVAO713 from Myceliophthora thermophila C1; 1.424e-42 | A0A2I1D0P8; Putative isoamyl alcohol oxidase; Aspergillus campestris (strain IBT 28561); 2.575e-87 | G9MX01; FAD-binding PCMH-type domain-containing protein; Hypocrea virens (strain Gv29-8 / FGSC 10586) (Gliocladium virens) (Trichoderma virens); 4.968e-79 |
| XANPAGTX0501_005715-T1 | cl55 | FAD linked oxidase | Upregulated in lichen | 0.91 | 95.06540 | 570 | IPR006094 FAD linked oxidase, N-terminal;IPR012951 Berberine/berberine-like;IPR016166 FAD-binding domain, PCMH-type;IPR036318 FAD-binding, type PCMH-like superfamily | AA7 | NA | Non-antimicrobial | 6F73; Crystal structure of VAO-type flavoprotein MtVAO615 at pH 5.0 from Myceliophthora thermophila C1; 4.411e-65 | 6F74; Crystal structure of VAO-type flavoprotein MtVAO713 from Myceliophthora thermophila C1; 2.097e-49 | A0A4Z1FDN5; FAD-binding PCMH-type domain-containing protein; Botrytis paeoniae; 1.168e-73 | A0A7D8UU14; FAD-linked oxidoreductase ZEB1; Lachnellula cervina; 6.139e-73 |
| XANPAGTX0501_000085-T1 | cl56 | flavoprotein EncM | Non-DGE | 0.88 | 90.60880 | 525 | IPR006094 FAD linked oxidase, N-terminal;IPR012951 Berberine/berberine-like;IPR016166 FAD-binding domain, PCMH-type;IPR016167 FAD-binding, type PCMH, subdomain 1;IPR016169 FAD-binding, type PCMH, subdomain 2;IPR036318 FAD-binding, type PCMH-like superfamily | AA7 | NA | Non-antimicrobial | 6FYD; The crystal structure of EncM T139V mutant; 1.714e-28 | 6FYE; The crystal structure of EncM H138T mutant; 2.418e-28 | A0A2V1CD15; FAD-binding domain-containing protein; Cadophora sp. DSE1049; 2.715e-63 | A0A5N6T9G9; FAD-binding PCMH-type domain-containing protein; Aspergillus pseudotamarii; 1.602e-55 |
| XANPAGTX0501_000553-T1 | cl56 | flavoprotein EncM | Non-DGE | 0.88 | 89.92460 | 500 | IPR006094 FAD linked oxidase, N-terminal;IPR016166 FAD-binding domain, PCMH-type;IPR016167 FAD-binding, type PCMH, subdomain 1;IPR016169 FAD-binding, type PCMH, subdomain 2;IPR036318 FAD-binding, type PCMH-like superfamily | AA7 | NA | Antimicrobial | 6FYG; The crystal structure of EncM V135T mutant; 2.529e-32 | 6FYF; The crystal structure of EncM V135M mutant; 3.395e-32 | A0A7C8MFV8; FAD-binding PCMH-type domain-containing protein; Xylaria multiplex; 2.738e-56 | A0A0N0V6G3; 6-hydroxy-d-nicotine oxidase; Fusarium langsethiae; 1.266e-55 |
| XANPAGTX0501_000933-T1 | cl56 | flavoprotein EncM | Non-DGE | 0.69 | 72.45520 | 225 | IPR006094 FAD linked oxidase, N-terminal;IPR036318 FAD-binding, type PCMH-like superfamily | NA | NA | Antimicrobial | 6YJI; Structure of FgCelDH7C; 5.653e-06 | 5I1V; Crystal structure of CrmK, a flavoenzyme involved in the shunt product recycling mechanism in caerulomycin biosynthesis; 6.649e-05 | A0A2C5YLF8; FAD-binding PCMH-type domain-containing protein; Ophiocordyceps camponoti-rufipedis; 2.403e-11 | A0A369HF07; FAD-binding PCMH-type domain-containing protein; Ophiocordyceps camponoti-saundersi (nom. inval.); 2.327e-10 |
| XANPAGTX0501_000935-T1 | cl56 | flavoprotein EncM | Non-DGE | 0.89 | 93.06261 | 510 | IPR006094 FAD linked oxidase, N-terminal;IPR012951 Berberine/berberine-like;IPR016166 FAD-binding domain, PCMH-type;IPR036318 FAD-binding, type PCMH-like superfamily | AA7 | NA | Non-antimicrobial | 6FYC; The crystal structure of EncM L144M mutant complex with dioxygen under 15 bars O2 pressure; 1.226e-34 | 6FYG; The crystal structure of EncM V135T mutant; 2.009e-34 | U1GF15; FAD-binding PCMH-type domain-containing protein; Endocarpon pusillum (strain Z07020 / HMAS-L-300199) (Lichen-forming fungus); 1.102e-73 | A0A0S7DZK1; deleted; ; 7.946e-73 |
| XANPAGTX0501_001002-T1 | cl56 | flavoprotein EncM | Non-DGE | 0.67 | 71.09031 | 292 | IPR006094 FAD linked oxidase, N-terminal;IPR016166 FAD-binding domain, PCMH-type;IPR036318 FAD-binding, type PCMH-like superfamily | AA7 | NA | Non-antimicrobial | 2BVG; Crystal structure of 6-hydoxy-D-nicotine oxidase from Arthrobacter nicotinovorans. Crystal Form 1 (P21); 2.596e-12 | 6FYG; The crystal structure of EncM V135T mutant; 1.019e-10 | A0A066XIG8; Putative FAD binding domain-containing protein; Colletotrichum sublineola (Sorghum anthracnose fungus); 3.909e-23 | A0A6G1NQF4; deleted; ; 9.308e-23 |
| XANPAGTX0501_001704-T1 | cl56 | flavoprotein EncM | Non-DGE | 0.9 | 92.45737 | 525 | IPR006094 FAD linked oxidase, N-terminal;IPR016166 FAD-binding domain, PCMH-type;IPR036318 FAD-binding, type PCMH-like superfamily | AA7 | NA | Non-antimicrobial | 3W8X; The complex structure of EncM with trifluorotriketide; 6.867e-26 | 6FYF; The crystal structure of EncM V135M mutant; 1.02e-25 | A0A3M7FU59; FAD-binding PCMH-type domain-containing protein; Hortaea werneckii; 1.198e-58 | A0A3M7CH44; FAD-binding PCMH-type domain-containing protein; Hortaea werneckii; 5.208e-58 |
| XANPAGTX0501_001974-T1 | cl56 | flavoprotein EncM | Upregulated in culture | 0.9 | 93.44082 | 500 | IPR006094 FAD linked oxidase, N-terminal;IPR016166 FAD-binding domain, PCMH-type;IPR016167 FAD-binding, type PCMH, subdomain 1;IPR016169 FAD-binding, type PCMH, subdomain 2;IPR036318 FAD-binding, type PCMH-like superfamily | AA7 | NA | Antimicrobial | 3W8X; The complex structure of EncM with trifluorotriketide; 5.82e-30 | 6FYD; The crystal structure of EncM T139V mutant; 8.673e-30 | A0A1W5CXF7; Uncharacterized conserved protein UCP028846; Lasallia pustulata; 7.835e-53 | A0A5M8PLK7; FAD-binding PCMH-type domain-containing protein; Lasallia pustulata; 2.45e-52 |
| XANPAGTX0501_002283-T1 | cl56 | flavoprotein EncM | Non-DGE | 0.89 | 90.04836 | 519 | IPR006094 FAD linked oxidase, N-terminal;IPR016166 FAD-binding domain, PCMH-type;IPR016167 FAD-binding, type PCMH, subdomain 1;IPR016169 FAD-binding, type PCMH, subdomain 2;IPR036318 FAD-binding, type PCMH-like superfamily | AA7 | NA | Non-antimicrobial | 6FYE; The crystal structure of EncM H138T mutant; 4.851e-27 | 3W8X; The complex structure of EncM with trifluorotriketide; 4.851e-27 | A0A5M8PCC7; FAD-binding PCMH-type domain-containing protein; Lasallia pustulata; 1.16e-65 | A0A0F8A5J6; FAD-binding PCMH-type domain-containing protein; Hirsutella minnesotensis 3608; 2.187e-49 |
| XANPAGTX0501_002304-T1 | cl56 | flavoprotein EncM | Non-DGE | 0.9 | 91.86230 | 526 | IPR006094 FAD linked oxidase, N-terminal;IPR016166 FAD-binding domain, PCMH-type;IPR036318 FAD-binding, type PCMH-like superfamily | AA7 | NA | Antimicrobial | 6FYF; The crystal structure of EncM V135M mutant; 4.717e-27 | 6FYE; The crystal structure of EncM H138T mutant; 7.378e-27 | T0JZW8; FAD-binding PCMH-type domain-containing protein; Colletotrichum gloeosporioides (strain Cg-14) (Anthracnose fungus) (Glomerella cingulata); 2.231e-49 | A0A0B7KS85; FAD-binding PCMH-type domain-containing protein; Bionectria ochroleuca (Gliocladium roseum); 4.127e-49 |
| XANPAGTX0501_003872-T1 | cl56 | flavoprotein EncM | Non-DGE | 0.89 | 93.21708 | 489 | IPR006094 FAD linked oxidase, N-terminal;IPR012951 Berberine/berberine-like;IPR016166 FAD-binding domain, PCMH-type;IPR036318 FAD-binding, type PCMH-like superfamily | AA7 | NA | Non-antimicrobial | 6FYE; The crystal structure of EncM H138T mutant; 1.21e-30 | 6FYF; The crystal structure of EncM V135M mutant; 1.147e-29 | A0A6A6CZV0; FAD-binding PCMH-type domain-containing protein; Zasmidium cellare ATCC 36951; 3.455e-62 | A0A179F141; FAD binding domain-containing protein; Pochonia chlamydosporia 170; 6.244e-62 |
| XANPAGTX0501_005256-T1 | cl56 | flavoprotein EncM | Upregulated in lichen | 0.91 | 93.62436 | 484 | IPR006094 FAD linked oxidase, N-terminal;IPR012951 Berberine/berberine-like;IPR016166 FAD-binding domain, PCMH-type;IPR036318 FAD-binding, type PCMH-like superfamily | AA7 | NA | Non-antimicrobial | 6FYG; The crystal structure of EncM V135T mutant; 4.358e-34 | 6FYE; The crystal structure of EncM H138T mutant; 4.873e-34 | A0A0U1LM91; FAD-binding PCMH-type domain-containing protein; Talaromyces islandicus (Penicillium islandicum); 2.488e-72 | A0A6A5XLC8; FAD binding domain-containing protein; Aaosphaeria arxii CBS 175.79; 1.313e-70 |
| XANPAGTX0501_005691-T1 | cl56 | flavoprotein EncM | Upregulated in culture | 0.91 | 93.68542 | 528 | IPR006094 FAD linked oxidase, N-terminal;IPR016166 FAD-binding domain, PCMH-type;IPR036318 FAD-binding, type PCMH-like superfamily | AA7 | NA | Non-antimicrobial | 6FYE; The crystal structure of EncM H138T mutant; 7.372e-28 | 6FYF; The crystal structure of EncM V135M mutant; 7.807e-28 | A0A6A7B452; FAD binding domain-containing protein; Plenodomus tracheiphilus IPT5; 6.701e-66 | A0A6A5RB18; FAD binding domain-containing protein; Didymella exigua CBS 183.55; 2.971e-65 |
| XANPAGTX0501_005748-T1 | cl56 | flavoprotein EncM | Non-DGE | 0.89 | 92.55604 | 508 | IPR006094 FAD linked oxidase, N-terminal;IPR012951 Berberine/berberine-like;IPR016166 FAD-binding domain, PCMH-type;IPR016167 FAD-binding, type PCMH, subdomain 1;IPR016169 FAD-binding, type PCMH, subdomain 2;IPR036318 FAD-binding, type PCMH-like superfamily | AA7 | NA | Non-antimicrobial | 6FYE; The crystal structure of EncM H138T mutant; 1.14e-35 | 6FYG; The crystal structure of EncM V135T mutant; 2.093e-35 | A0A0S7DZK1; deleted; ; 2.819e-67 | U1GF15; FAD-binding PCMH-type domain-containing protein; Endocarpon pusillum (strain Z07020 / HMAS-L-300199) (Lichen-forming fungus); 2.853e-65 |
| XANPAGTX0501_007268-T1 | cl56 | flavoprotein EncM | Upregulated in lichen | 0.89 | 92.37537 | 512 | IPR006094 FAD linked oxidase, N-terminal;IPR016166 FAD-binding domain, PCMH-type;IPR036318 FAD-binding, type PCMH-like superfamily | AA7 | NA | Non-antimicrobial | 6FYF; The crystal structure of EncM V135M mutant; 7.054e-32 | 6FYG; The crystal structure of EncM V135T mutant; 4.082e-31 | A0A0U5HGI3; FAD-binding PCMH-type domain-containing protein; Aspergillus calidoustus; 2.943e-60 | A0A175WGG7; 6-hydroxy-D-nicotine oxidase; Madurella mycetomatis; 1.358e-59 |
| XANPAGTX0501_010693-T1 | cl56 | flavoprotein EncM | Upregulated in lichen | 0.91 | 93.68269 | 528 | IPR006094 FAD linked oxidase, N-terminal;IPR016166 FAD-binding domain, PCMH-type;IPR036318 FAD-binding, type PCMH-like superfamily | AA7 | NA | Non-antimicrobial | 6FYF; The crystal structure of EncM V135M mutant; 1.479e-26 | 3W8X; The complex structure of EncM with trifluorotriketide; 1.479e-26 | A0A6A7B452; FAD binding domain-containing protein; Plenodomus tracheiphilus IPT5; 3.623e-65 | A0A6A5RB18; FAD binding domain-containing protein; Didymella exigua CBS 183.55; 5.357e-64 |
| XANPAGTX0501_000197-T1 | cl57 | SGNH hydrolase domain | Non-DGE | 0.71 | 78.66519 | 289 | IPR013830 SGNH hydrolase-type esterase domain;IPR036514 SGNH hydrolase superfamily | NA | NA | Non-antimicrobial | 1ES9; X-RAY CRYSTAL STRUCTURE OF R22K MUTANT OF THE MAMMALIAN BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASES (PAF-AH); 1.677e-09 | 1U8U; E. coli Thioesterase I/Protease I/Lysophospholiase L1 in complexed with octanoic acid; 8.877e-09 | A0A1S9RGR2; SGNH hydrolase-type esterase domain-containing protein; Penicillium brasilianum; 2.107e-23 | A0A1E1L4F0; Related to esterase; Rhynchosporium agropyri; 5.195e-22 |
| XANPAGTX0501_007467-T1 | cl57 | SGNH hydrolase domain | Upregulated in lichen | 0.86 | 82.90107 | 571 | IPR013830 SGNH hydrolase-type esterase domain;IPR036514 SGNH hydrolase superfamily | CE3 | NA | Antimicrobial | 7PZH; Phocaeicola vulgatus sialic acid esterase at 2.06 Angstrom resolution; 2.78e-06 | 7PZG; Phocaeicola vulgatus sialic acid esterase at 1.44 Angstrom resolution; 9.066e-06 | W7N164; SGNH hydrolase-type esterase domain-containing protein; Gibberella moniliformis (strain M3125 / FGSC 7600) (Maize ear and stalk rot fungus) (Fusarium verticillioides); 5.002e-19 | A0A4E9DHT3; SGNH hydrolase-type esterase domain-containing protein; Gibberella zeae (Wheat head blight fungus) (Fusarium graminearum); 2.645e-18 |
| XANPAGTX0501_003572-T1 | cl58 | GDSL lipase/esterase | Upregulated in lichen | 0.81 | 82.49739 | 360 | IPR036514 SGNH hydrolase superfamily | CE16 | NA | Antimicrobial | 8H0B; Structure of the thermolabile hemolysin from Vibrio alginolyticus (in complex with oleic acid); 1.129e-12 | 8H0C; Structure of the thermolabile hemolysin from Vibrio alginolyticus (in complex with arachidonic acid); 2.153e-12 | M3AVB5; Carbohydrate esterase family 16 protein; Pseudocercospora fijiensis (strain CIRAD86) (Black leaf streak disease fungus) (Mycosphaerella fijiensis); 4.657e-36 | A0A3M7B1B8; Carbohydrate esterase family 16 protein; Hortaea werneckii; 5.553e-36 |
| XANPAGTX0501_005514-T1 | cl58 | GDSL lipase/esterase | Non-DGE | 0.84 | 86.40883 | 358 | IPR001087 GDSL lipase/esterase;IPR036514 SGNH hydrolase superfamily | CE16 | NA | Non-antimicrobial | 8D8X; Crystal structure of ChoE in complex with acetate and thiocholine (crystal form 2); 4.311e-12 | 6UR1; Crystal structure of ChoE S38A mutant in complex with acetate and acetylthiocholine; 8.311e-12 | A0A6A6H321; Carbohydrate esterase family 16 protein; Viridothelium virens; 3.49e-32 | S3DZ45; SGNH hydrolase; Glarea lozoyensis (strain ATCC 20868 / MF5171); 1.072e-29 |
| XANPAGTX0501_009655-T1 | cl58 | GDSL lipase/esterase | Non-DGE | 0.86 | 88.23770 | 365 | IPR001087 GDSL lipase/esterase;IPR036514 SGNH hydrolase superfamily | CE16 | NA | Non-antimicrobial | 8A25; Lysophospholipase PlaA from Legionella pneumophila str. Corby - complex with PEG fragment; 1.295e-12 | 8D8X; Crystal structure of ChoE in complex with acetate and thiocholine (crystal form 2); 2.664e-12 | W3WNK7; Acetylesterase; Pestalotiopsis fici (strain W106-1 / CGMCC3.15140); 3.124e-26 | A0A6A6CTA7; Carbohydrate esterase family 16 protein; Zasmidium cellare ATCC 36951; 2.957e-23 |
| XANPAGTX0501_001127-T1 | cl59 | GH128 | Upregulated in lichen | 0.67 | 77.67610 | 400 | IPR017853 Glycoside hydrolase superfamily;IPR024655 Asl1-like, glycosyl hydrolase catalytic domain | GH128 | NA | Antimicrobial | 6UAZ; Crystal structure of a GH128 (subgroup III) curdlan-specific exo-beta-1,3-glucanase from Blastomyces gilchristii (BgGH128_III) in complex with glucose; 2.53e-20 | 6UB8; Crystal structure of a GH128 (subgroup VI) exo-beta-1,3-glucanase from Aureobasidium namibiae (AnGH128_VI); 2.873e-13 | A0A4U0XZ18; Asl1-like glycosyl hydrolase catalytic domain-containing protein; Friedmanniomyces simplex; 2.147e-24 | A0A4S9M8I3; Asl1-like glycosyl hydrolase catalytic domain-containing protein; Aureobasidium pullulans (Black yeast) (Pullularia pullulans); 4.826e-22 |
| XANPAGTX0501_001832-T1 | cl59 | GH128 | Upregulated in lichen | 0.61 | 70.01544 | 421 | IPR017853 Glycoside hydrolase superfamily;IPR024655 Asl1-like, glycosyl hydrolase catalytic domain | GH128 | NA | Antimicrobial | 6UBC; Crystal structure of a GH128 (subgroup VII) oligosaccharide-binding protein from Cryptococcus neoformans (CnGH128_VII); 4.359e-10 | 4QAW; Structure of modular Xyn30D from Paenibacillus barcinonensis; 2.911e-06 | A0A2K0TQW1; Asl1-like glycosyl hydrolase catalytic domain-containing protein; Trichoderma gamsii; 1.125e-29 | A0A5M3MMY0; Asl1-like glycosyl hydrolase catalytic domain-containing protein; Coniophora puteana (strain RWD-64-598) (Brown rot fungus); 6.626e-29 |
| XANPAGTX0501_004870-T1 | cl59 | GH128 | Non-DGE | 0.84 | 90.95345 | 229 | IPR017853 Glycoside hydrolase superfamily;IPR024655 Asl1-like, glycosyl hydrolase catalytic domain | GH128 | NA | Non-antimicrobial | 6UB4; Crystal structure (C2 form) of a GH128 (subgroup IV) endo-beta-1,3-glucanase from Lentinula edodes (LeGH128_IV) in complex with laminaritriose; 1.018e-11 | 6UB8; Crystal structure of a GH128 (subgroup VI) exo-beta-1,3-glucanase from Aureobasidium namibiae (AnGH128_VI); 2.325e-11 | A0A6G1GWR7; Glycoside hydrolase family 128 protein; Aulographum hederae CBS 113979; 5.252e-31 | A0A6G1JBK6; Glycoside hydrolase family 128 protein; Lentithecium fluviatile CBS 122367; 1.04e-29 |
| XANPAGTX0501_005416-T1 | cl59 | GH128 | Non-DGE | 0.71 | 75.55260 | 350 | IPR017853 Glycoside hydrolase superfamily;IPR024655 Asl1-like, glycosyl hydrolase catalytic domain | GH128 | NA | Antimicrobial | 6UFZ; Crystal structure of a GH128 (subgroup I) endo-beta-1,3-glucanase (E199Q mutant) from Amycolatopsis mediterranei (AmGH128_I); 7.325e-17 | 6UAR; Crystal structure of a GH128 (subgroup I) endo-beta-1,3-glucanase from Amycolatopsis mediterranei (AmGH128_I) in complex with laminaritriose; 2.379e-16 | A0A5M8PWH0; Asl1-like glycosyl hydrolase catalytic domain-containing protein; Lasallia pustulata; 1.03e-23 | A0A818Z082; Asl1-like glycosyl hydrolase catalytic domain-containing protein; Rotaria sordida; 9.788e-18 |
| XANPAGTX0501_008596-T1 | cl59 | GH128 | Non-DGE | 0.83 | 83.71293 | 300 | IPR017853 Glycoside hydrolase superfamily;IPR024655 Asl1-like, glycosyl hydrolase catalytic domain | GH128 | NA | Antimicrobial | 6UB7; Crystal structure of a GH128 (subgroup V) exo-beta-1,3-glucanase from Cryptococcus neoformans (CnGH128_V); 3.067e-12 | 6UBD; Crystal structure of a GH128 (subgroup VII) oligosaccharide-binding protein from Trichoderma gamsii (TgGH128_VII); 6.315e-12 | A0A2K0TQW1; Asl1-like glycosyl hydrolase catalytic domain-containing protein; Trichoderma gamsii; 1.181e-19 | A0A5M3MMY0; Asl1-like glycosyl hydrolase catalytic domain-containing protein; Coniophora puteana (strain RWD-64-598) (Brown rot fungus); 2.432e-19 |
| XANPAGTX0501_006873-T1 | cl60 | Spherulation | Non-DGE | 0.9 | 94.67271 | 258 | IPR021986 Spherulation-specific family 4 | GH135 | NA | Non-antimicrobial | 5D6T; Crystal Structure of Aspergillus clavatus Sph3 in complex with GalNAc; 1.124e-18 | 7OMS; Bs164 in complex with mannocyclophellitol aziridine; 0.0007705 | A0A370U1V6; Spherulation-specific family 4; Venustampulla echinocandica; 8.008e-24 | S3DAA7; Spherulin-4; Glarea lozoyensis (strain ATCC 20868 / MF5171); 8.705e-23 |
| XANPAGTX0501_009750-T1 | cl60 | Spherulation | Non-DGE | 0.73 | 78.92304 | 158 | IPR021986 Spherulation-specific family 4 | GH135 | NA | Non-antimicrobial | 5D6T; Crystal Structure of Aspergillus clavatus Sph3 in complex with GalNAc; 3.322e-05 | NA | A0A1W5DBE1; Spherulation-specific family 4; Lasallia pustulata; 1.304e-06 | A0A6G1H548; 1,3-beta-glucanosyltransferase; Aulographum hederae CBS 113979; 4.207e-06 |
| XANPAGTX0501_004284-T1 | cl61 | GH71 | Non-DGE | 0.88 | 89.86701 | 432 | IPR005197 Glycoside hydrolase family 71 | GH71 | NA | Non-antimicrobial | NA | NA | A0A5M9JWB1; Glycoside hydrolase family 71 protein; Monilinia fructicola (Brown rot fungus) (Ciboria fructicola); 6.415e-36 | A0A2T3APP8; Glycoside hydrolase family 71 protein; Amorphotheca resinae ATCC 22711; 9.088e-36 |
| XANPAGTX0501_009731-T1 | cl61 | GH71 | Upregulated in lichen | 0.72 | 76.92287 | 647 | IPR005197 Glycoside hydrolase family 71 | GH71 | NA | Non-antimicrobial | 6ZFQ; Structure of the catalytic domain of human endo-alpha-mannosidase MANEA in complex with bis-tris; 1.055e-08 | 3KL3; Crystal structure of Ligand bound XynC; 0.0002456 | A0A7C8NY73; Mutanase; Orbilia oligospora (Nematode-trapping fungus) (Arthrobotrys oligospora); 1.419e-76 | A0A093ZD78; Mutanase; Pseudogymnoascus sp. VKM F-4246; 7.507e-76 |
| XANPAGTX0501_007944-T1 | cl62 | GH20 | Non-DGE | 0.92 | 92.37711 | 599 | IPR015883 Glycoside hydrolase family 20, catalytic domain;IPR017853 Glycoside hydrolase superfamily;IPR025705 Beta-hexosaminidase;IPR029018 Beta-hexosaminidase-like, domain 2;IPR029019 Beta-hexosaminidase, eukaryotic type, N-terminal | GH20 | NA | Antimicrobial | 3OZP; Crystal Structure of insect beta-N-acetyl-D-hexosaminidase OfHex1 complexed with PUGNAc; 2.608e-43 | 5Y0V; Crystal Structure of insect beta-N-acetyl-D-hexosaminidase OfHex1 complexed with berberine; 3.09e-43 | A0A3M6WFM8; beta-N-acetylhexosaminidase (EC 3.2.1.52); Hortaea werneckii; 8.129e-80 | A0A3M7BSS0; beta-N-acetylhexosaminidase (EC 3.2.1.52); Hortaea werneckii; 6.255e-75 |
| XANPAGTX0501_008404-T2 | cl62 | GH20 | Non-DGE | 0.9 | 89.93681 | 590 | IPR015883 Glycoside hydrolase family 20, catalytic domain;IPR017853 Glycoside hydrolase superfamily;IPR025705 Beta-hexosaminidase;IPR029018 Beta-hexosaminidase-like, domain 2;IPR029019 Beta-hexosaminidase, eukaryotic type, N-terminal | GH20 | NA | Non-antimicrobial | 5Y0V; Crystal Structure of insect beta-N-acetyl-D-hexosaminidase OfHex1 complexed with berberine; 2.654e-46 | 3OZP; Crystal Structure of insect beta-N-acetyl-D-hexosaminidase OfHex1 complexed with PUGNAc; 4.219e-46 | A0A545UNY0; Beta-hexosaminidase (EC 3.2.1.52); Cordyceps javanica; 2.017e-63 | A0A2U3EF51; Beta-hexosaminidase (EC 3.2.1.52); Purpureocillium lilacinum (Paecilomyces lilacinus); 1.986e-56 |
| XANPAGTX0501_005771-T1 | cl63 | GH5 | Upregulated in lichen | 0.92 | 93.06367 | 403 | IPR001547 Glycoside hydrolase, family 5;IPR017853 Glycoside hydrolase superfamily | GH5 | NA | Non-antimicrobial | 2PF0; F258I mutant of EXO-B-(1,3)-GLUCANASE FROM CANDIDA ALBICANS at 1.9 A; 1.402e-21 | 2PB1; Exo-B-(1,3)-Glucanase from Candida Albicans in complex with unhydrolysed and covalently linked 2,4-dinitrophenyl-2-deoxy-2-fluoro-B-D-glucopyranoside at 1.9 A; 8.811e-21 | A0A5J5EJS4; glucan endo-1,6-beta-glucosidase (EC 3.2.1.75) (Beta-1,6-glucanase B) (Endo-1,6-beta-D-glucanase B) (Endo-1,6-beta-glucanase B); Sphaerosporella brunnea; 1.055e-55 | A0A397HJG6; glucan endo-1,6-beta-glucosidase (EC 3.2.1.75) (Beta-1,6-glucanase B) (Endo-1,6-beta-D-glucanase B) (Endo-1,6-beta-glucanase B); Aspergillus thermomutatus; 1.742e-52 |
| XANPAGTX0501_005824-T1 | cl63 | GH5 | Non-DGE | 0.9 | 92.80199 | 418 | IPR001547 Glycoside hydrolase, family 5;IPR017853 Glycoside hydrolase superfamily | GH5 | NA | Antimicrobial | 4M82; The structure of E292S glycosynthase variant of exo-1,3-beta-glucanase from Candida albicans complexed with p-nitrophenyl-gentiobioside (product) at 1.6A resolution; 1.877e-49 | 2PC8; E292Q mutant of EXO-B-(1,3)-Glucanase from Candida Albicans in complex with two separately bound glucopyranoside units at 1.8 A; 5.568e-49 | A0A559M7G4; glucan 1,3-beta-glucosidase (EC 3.2.1.58); Lachnellula willkommii; 7.832e-58 | A0A420IS96; glucan 1,3-beta-glucosidase (EC 3.2.1.58); Golovinomyces cichoracearum; 2.427e-56 |
| XANPAGTX0501_009065-T1 | cl63 | GH5 | Non-DGE | 0.9 | 92.81578 | 419 | IPR001547 Glycoside hydrolase, family 5;IPR017853 Glycoside hydrolase superfamily;IPR018087 Glycoside hydrolase, family 5, conserved site | GH5 | NA | Antimicrobial | 1EQP; EXO-B-(1,3)-GLUCANASE FROM CANDIDA ALBICANS; 3.583e-49 | 2PC8; E292Q mutant of EXO-B-(1,3)-Glucanase from Candida Albicans in complex with two separately bound glucopyranoside units at 1.8 A; 1.207e-48 | A0A178AJ34; Glycoside hydrolase; Stagonospora sp. SRC1lsM3a; 1.595e-55 | K5X1J2; glucan 1,3-beta-glucosidase (EC 3.2.1.58); Phanerochaete carnosa (strain HHB-10118-sp) (White-rot fungus) (Peniophora carnosa); 1.233e-45 |
| XANPAGTX0501_002331-T1 | cl64 | GH5 | Upregulated in lichen | 0.64 | 70.62403 | 573 | IPR001547 Glycoside hydrolase, family 5;IPR017853 Glycoside hydrolase superfamily;IPR018087 Glycoside hydrolase, family 5, conserved site | GH5 | NA | Antimicrobial | 3QR3; Crystal Structure of Cel5A (EG2) from Hypocrea jecorina (Trichoderma reesei); 4.629e-49 | 5D8Z; Structrue of a lucidum protein; 1.253e-45 | A0A1B8CR24; cellulase (EC 3.2.1.4); Pseudogymnoascus sp. WSF 3629; 3.403e-46 | A0A094H9E2; cellulase (EC 3.2.1.4); Pseudogymnoascus sp. VKM F-4520 (FW-2644); 7.692e-46 |
| XANPAGTX0501_007383-T1 | cl64 | GH5 | Non-DGE | 0.88 | 90.37385 | 405 | IPR001547 Glycoside hydrolase, family 5;IPR017853 Glycoside hydrolase superfamily | GH5 | NA | Non-antimicrobial | 3ZIZ; Crystal structure of Podospora anserina GH5 beta-(1,4)-mannanase; 3.625e-43 | 3WFL; Crtstal structure of glycoside hydrolase family 5 beta-mannanase from Talaromyces trachyspermus; 2.356e-42 | A0A162LAP6; mannan endo-1,4-beta-mannosidase (EC 3.2.1.78); Niveomyces insectorum RCEF 264; 4.197e-44 | A0A4V5NGM5; mannan endo-1,4-beta-mannosidase (EC 3.2.1.78); Cryomyces minteri; 6.802e-44 |
| XANPAGTX0501_001051-T1 | cl65 | GH72 | Upregulated in culture | 0.7 | 76.37445 | 416 | IPR017853 Glycoside hydrolase superfamily | GH17 | NA | Non-antimicrobial | 8AKP; Crystal structure of the catalytic domain of G7048 from Penicillium sumatraense; 2.194e-15 | 4WTS; Active-site mutant of Rhizomucor miehei beta-1,3-glucanosyltransferase in complex with laminaritriose; 5.135e-14 | A0A395SU71; Probable beta-glucosidase btgE (Beta-D-glucoside glucohydrolase btgE) (Cellobiase btgE) (Gentiobiase btgE); Fusarium longipes; 9.187e-34 | A0A2T4C9H5; Probable beta-glucosidase btgE (Beta-D-glucoside glucohydrolase btgE) (Cellobiase btgE) (Gentiobiase btgE); Trichoderma longibrachiatum ATCC 18648; 2.681e-33 |
| XANPAGTX0501_001599-T1 | cl65 | GH72 | Non-DGE | 0.83 | 86.79342 | 456 | IPR004886 Glucanosyltransferase;IPR017853 Glycoside hydrolase superfamily | GH72 | NA | Non-antimicrobial | 5O9Y; Crystal structure of ScGas2 in complex with compound 11; 4.595e-37 | 5O9O; Crystal structure of ScGas2 in complex with compound 7.; 1.36e-36 | A0A1W5D808; 1,3-beta-glucanosyltransferase (EC 2.4.1.-); Lasallia pustulata; 3.523e-65 | A0A420J2Q4; 1,3-beta-glucanosyltransferase (EC 2.4.1.-); Golovinomyces cichoracearum; 2.868e-62 |
| XANPAGTX0501_003500-T1 | cl65 | GH72 | Non-DGE | 0.67 | 80.84327 | 388 | IPR000490 Glycoside hydrolase family 17;IPR017853 Glycoside hydrolase superfamily | GH17 | NA | Non-antimicrobial | 4WTS; Active-site mutant of Rhizomucor miehei beta-1,3-glucanosyltransferase in complex with laminaritriose; 2.36e-16 | 4WTP; Crystal structure of glycoside hydrolase family 17 beta-1,3-glucanosyltransferase from Rhizomucor miehei; 9.217e-16 | A0A0F4GCX7; Cell wall glucanase like protein; Zymoseptoria brevis; 1.213e-36 | A0A1X7S612; Methyltransferase small domain-containing protein; Zymoseptoria tritici ST99CH_3D7; 1.2e-35 |
| XANPAGTX0501_003503-T1 | cl65 | GH72 | Non-DGE | 0.85 | 87.99634 | 538 | IPR004886 Glucanosyltransferase;IPR012946 X8 domain;IPR017853 Glycoside hydrolase superfamily | GH72 | NA | Non-antimicrobial | 2W61; Saccharomyces cerevisiae Gas2p apostructure (E176Q mutant); 1.777e-52 | 5OA2; Crystal structure of ScGas2 in complex with compound 8; 2e-52 | A0A3M7ML87; 1,3-beta-glucanosyltransferase (EC 2.4.1.-); Chaetothyriales sp. CBS 132003; 2.491e-68 | A0A074VCF9; 1,3-beta-glucanosyltransferase (EC 2.4.1.-); Aureobasidium melanogenum CBS 110374; 1.029e-65 |
| XANPAGTX0501_004305-T1 | cl65 | GH72 | Non-DGE | 0.86 | 87.30977 | 481 | IPR004886 Glucanosyltransferase;IPR017853 Glycoside hydrolase superfamily | GH72 | NA | Non-antimicrobial | 5OA2; Crystal structure of ScGas2 in complex with compound 8; 8.071e-34 | 5FIH; SACCHAROMYCES CEREVISIAE GAS2P (E176Q MUTANT) IN COMPLEX WITH LAMINARITETRAOSE AND LAMINARIPENTAOSE; 2.427e-33 | A0A6A6QJZ1; 1,3-beta-glucanosyltransferase (EC 2.4.1.-); Lophium mytilinum; 2.102e-68 | A0A6A6V308; 1,3-beta-glucanosyltransferase (EC 2.4.1.-); Sporormia fimetaria CBS 119925; 1.374e-65 |
| XANPAGTX0501_004466-T1 | cl65 | GH72 | Non-DGE | 0.56 | 80.16331 | 601 | IPR000490 Glycoside hydrolase family 17;IPR017853 Glycoside hydrolase superfamily;IPR018620 Ubiquitin 3 binding protein But2, C-terminal | NA | NA | Antimicrobial | 8AKP; Crystal structure of the catalytic domain of G7048 from Penicillium sumatraense; 6.144e-38 | 4WTP; Crystal structure of glycoside hydrolase family 17 beta-1,3-glucanosyltransferase from Rhizomucor miehei; 5.218e-17 | N4VAI7; deleted; ; 1.886e-44 | A0A3N2Q222; Probable glucan endo-1,3-beta-glucosidase eglC (EC 3.2.1.39) (Endo-1,3-beta-glucanase eglC) (Laminarinase eglC); Sodiomyces alkalinus F11; 9.08e-44 |
| XANPAGTX0501_006257-T1 | cl65 | GH72 | Upregulated in lichen | 0.89 | 94.78313 | 291 | IPR000490 Glycoside hydrolase family 17;IPR017853 Glycoside hydrolase superfamily | NA | NA | Antimicrobial | 8AKP; Crystal structure of the catalytic domain of G7048 from Penicillium sumatraense; 1.983e-32 | 4WTS; Active-site mutant of Rhizomucor miehei beta-1,3-glucanosyltransferase in complex with laminaritriose; 3.139e-22 | A0A2I0SA18; deleted; ; 1.918e-41 | A0A178CKP3; deleted; ; 6.839e-40 |
| XANPAGTX0501_007287-T1 | cl65 | GH72 | Non-DGE | 0.82 | 85.42341 | 434 | IPR004886 Glucanosyltransferase;IPR017853 Glycoside hydrolase superfamily | GH72 | NA | Non-antimicrobial | 5OA6; Crystal structure of ScGas2 in complex with compound 12; 1.396e-34 | 5O9Q; Crystal structure of ScGas2 in complex with compound 6; 1.396e-34 | A0A6A6TZ55; 1,3-beta-glucanosyltransferase (EC 2.4.1.-); Microthyrium microscopicum; 4.63e-54 | A0A0D1XJS0; 1,3-beta-glucanosyltransferase (EC 2.4.1.-); Verruconis gallopava; 2.182e-53 |
| XANPAGTX0501_006694-T1 | cl66 | No annotation | Upregulated in culture | 0.85 | 90.17522 | 341 | NA | NA | NA | Non-antimicrobial | NA | NA | A0A4S8T8Y1; Apple domain-containing protein; Aureobasidium pullulans (Black yeast) (Pullularia pullulans); 3.811e-41 | A0A074Y7S9; Apple domain-containing protein; Aureobasidium subglaciale (strain EXF-2481) (Aureobasidium pullulans var. subglaciale); 1.565e-39 |
| XANPAGTX0501_009026-T1 | cl66 | No annotation | Upregulated in lichen | 0.65 | 67.83616 | 177 | NA | NA | NA | Non-antimicrobial | NA | NA | NA | NA |
| XANPAGTX0501_001458-T1 | cl67 | Kremen-like | Upregulated in lichen | 0.64 | 78.90771 | 532 | IPR002889 Carbohydrate-binding WSC;IPR018535 Domain of unknown function DUF1996 | NA | NA | Antimicrobial | 7PZ2; Structure of the mechanosensor domain of Wsc1 from Saccharomyces cerevisiae; 4.487e-06 | 6SNW; Structure of Coxsackievirus A10 complexed with its receptor KREMEN1; 9.741e-06 | A0A1Y2AVJ5; WSC domain-containing protein; Naematelia encephala; 3.032e-38 | A0A1Y2B2Z9; WSC domain-containing protein; Naematelia encephala; 1.358e-34 |
| XANPAGTX0501_002771-T1 | cl67 | Kremen-like | Non-DGE | 0.61 | 75.45871 | 178 | IPR002889 Carbohydrate-binding WSC | AA2, AA5 | NA | Non-antimicrobial | 5FWW; Wnt modulator Kremen in complex with DKK1 (CRD2) and LRP6 (PE3PE4); 1.086e-07 | 6SNW; Structure of Coxsackievirus A10 complexed with its receptor KREMEN1; 3.365e-07 | A0A072PVC9; WSC domain-containing protein; Exophiala aquamarina CBS 119918; 2.666e-12 | A0A6A6P5T9; Heme peroxidase; Lineolata rhizophorae; 2.83e-12 |
| XANPAGTX0501_003112-T1 | cl67 | Kremen-like | Non-DGE | 0.9 | 93.07371 | 665 | IPR002889 Carbohydrate-binding WSC;IPR009880 Glyoxal oxidase, N-terminal;IPR011043 Galactose oxidase/kelch, beta-propeller;IPR013783 Immunoglobulin-like fold;IPR014756 Immunoglobulin E-set;IPR015202 Galactose oxidase-like, Early set domain;IPR037293 Galactose oxidase, central domain superfamily | AA2, AA5 | NA | Antimicrobial | 6STX; Copper oxidase from Colletotrichum graminicola; 4.114e-31 | 5LXZ; W288A mutant of GlxA from Streptomyces lividans: Cu-bound form; 4.81e-30 | A0A4V1XWP0; WSC domain-containing protein; Monosporascus sp. 5C6A; 5.601e-99 | A0A1Y2VRL5; Putative glyoxal oxidase; Hypoxylon sp. CI-4A; 3.044e-97 |
| XANPAGTX0501_004685-T1 | cl67 | Kremen-like | Non-DGE | 0.78 | 88.96366 | 913 | IPR002889 Carbohydrate-binding WSC;IPR009880 Glyoxal oxidase, N-terminal;IPR011043 Galactose oxidase/kelch, beta-propeller;IPR013783 Immunoglobulin-like fold;IPR014756 Immunoglobulin E-set;IPR015202 Galactose oxidase-like, Early set domain;IPR037293 Galactose oxidase, central domain superfamily | AA2, AA5 | NA | Non-antimicrobial | 6STX; Copper oxidase from Colletotrichum graminicola; 2.141e-33 | 6RYX; Copper oxidase from Colletotrichum graminicola; 4.446e-31 | A0A6G1JP04; Copper radical oxidase; Lentithecium fluviatile CBS 122367; 0 | A0A6A6RTD7; Galactose oxidase; Massarina eburnea CBS 473.64; 0 |
| XANPAGTX0501_004854-T1 | cl67 | Kremen-like | Non-DGE | 0.63 | 79.35459 | 181 | IPR002889 Carbohydrate-binding WSC | AA2, AA5 | NA | Non-antimicrobial | 5FWW; Wnt modulator Kremen in complex with DKK1 (CRD2) and LRP6 (PE3PE4); 3.968e-07 | 5FWU; Wnt modulator Kremen crystal form II at 2.8A; 7.84e-07 | A0A165GMI8; WSC-domain-containing protein; Xylona heveae (strain CBS 132557 / TC161); 6.159e-15 | A0A3D8RVQ0; WSC domain-containing protein; Coleophoma crateriformis; 6.159e-15 |
| XANPAGTX0501_005800-T1 | cl67 | Kremen-like | Non-DGE | 0.67 | 78.73468 | 1514 | IPR002889 Carbohydrate-binding WSC;IPR013783 Immunoglobulin-like fold | AA2, AA5 | NA | Non-antimicrobial | 7SQC; Ciliary C1 central pair apparatus isolated from Chlamydomonas reinhardtii; 5.29e-17 | 7PZ2; Structure of the mechanosensor domain of Wsc1 from Saccharomyces cerevisiae; 4.85e-05 | R8BN75; Putative wsc domain-containing protein; Phaeoacremonium minimum (strain UCR-PA7) (Esca disease fungus) (Togninia minima); 0 | A0A437AGZ5; WSC domain-containing protein; Arthrobotrys flagrans; 0 |
| XANPAGTX0501_009572-T1 | cl67 | Kremen-like | Non-DGE | 0.7 | 85.71615 | 794 | IPR002016 Haem peroxidase;IPR002889 Carbohydrate-binding WSC;IPR010255 Haem peroxidase superfamily | AA2, AA5 | NA | Antimicrobial | 8FF7; Cytosolic ascorbate peroxidase mutant from Panicum virgatum- ascorbate complex; 1.377e-08 | 3ZCY; Ascorbate peroxidase W41A-H42Y mutant; 1.615e-08 | A0A6A6P5T9; Heme peroxidase; Lineolata rhizophorae; 3.304e-90 | A0A370TW43; Heme peroxidase; Venustampulla echinocandica; 7.554e-86 |
| XANPAGTX0501_010118-T1 | cl67 | Kremen-like | Non-DGE | 0.52 | 74.70309 | 2081 | IPR002889 Carbohydrate-binding WSC;IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily | AA2, AA5 | NA | Non-antimicrobial | 7SQC; Ciliary C1 central pair apparatus isolated from Chlamydomonas reinhardtii; 8.1e-15 | 7SQC; Ciliary C1 central pair apparatus isolated from Chlamydomonas reinhardtii; 3.215e-13 | H0EM97; Putative fungistatic metabolite; Glarea lozoyensis (strain ATCC 74030 / MF5533); 9.154e-99 | A0A4T0C0S1; WSC-domain-containing protein; Aureobasidium pullulans (Black yeast) (Pullularia pullulans); 9.171e-72 |
| XANPAGTX0501_000163-T1 | cl68 | Ferritin-like | Upregulated in lichen | 0.86 | 91.00356 | 315 | IPR009078 Ferritin-like superfamily | NA | NA | Non-antimicrobial | NA | NA | A0A094BZK6; Ferritin-like diiron domain-containing protein; Pseudogymnoascus sp. VKM F-4513 (FW-928); 5.765e-39 | A0A0B7KBV2; Ferritin/DPS protein domain-containing protein; Bionectria ochroleuca (Gliocladium roseum); 3.362e-38 |
| XANPAGTX0501_002552-T1 | cl68 | Ferritin-like | Non-DGE | 0.87 | 89.67626 | 478 | NA | NA | NA | Antimicrobial | NA | NA | A0A5N6T127; Ferritin-like domain-containing protein; Aspergillus pseudotamarii; 2.84e-71 | A0A5M8PU89; Protein rds1; Lasallia pustulata; 1.359e-56 |
| XANPAGTX0501_000923-T1 | cl69 | Purple acid phosphatase-like | Upregulated in lichen | 0.92 | 92.24466 | 618 | IPR008963 Purple acid phosphatase-like, N-terminal;IPR018946 PhoD-like phosphatase, metallophosphatase domain;IPR032093 Phospholipase D, N-terminal;IPR038607 PhoD-like superfamily | NA | NA | Non-antimicrobial | 2YEQ; Structure of PhoD; 1.934e-48 | NA | A0A2C5ZCQ5; C2 domain-containing protein; Ophiocordyceps camponoti-rufipedis; 1.341e-92 | A0A4Q4UE84; PhoD-like phosphatase metallophosphatase domain-containing protein; Monosporascus sp. MC13-8B; 6.986e-90 |
| XANPAGTX0501_006265-T1 | cl69 | Purple acid phosphatase-like | Non-DGE | 0.91 | 90.39639 | 634 | IPR008963 Purple acid phosphatase-like, N-terminal;IPR018946 PhoD-like phosphatase, metallophosphatase domain;IPR032093 Phospholipase D, N-terminal;IPR038607 PhoD-like superfamily | NA | NA | Antimicrobial | 2YEQ; Structure of PhoD; 3.102e-53 | 6GJ9; PURPLE ACID PHYTASE FROM WHEAT ISOFORM B2 - REGENERATION COMPLEX; 2.269e-19 | A0A074VYT3; Phosphodiesterase/alkaline phosphatase D; Aureobasidium melanogenum CBS 110374; 0 | N4VQ28; deleted; ; 0 |
| XANPAGTX0501_004252-T1 | cl70 | AA9 | Non-DGE | 0.74 | 81.70142 | 466 | IPR001002 Chitin-binding, type 1;IPR005103 Auxiliary Activity family 9;IPR013087 Zinc finger C2H2-type;IPR018371 Chitin-binding, type 1, conserved site;IPR036861 Endochitinase-like superfamily | AA9 | NA | Antimicrobial | 5NLT; CvAA9A; 8.281e-22 | 6RS9; X-ray crystal structure of LsAA9B (xylotetraose soak); 2.967e-19 | A0A1W5D0F1; Multifunctional fusion protein [Includes: Endo-beta-1,4-glucanase D (Endoglucanase D) (EC 3.2.1.4) (Carboxymethylcellulase D) (Cellulase D); Histone H4]; Lasallia pustulata; 1.356e-49 | A0A397IHD3; Endo-beta-1,4-glucanase D (Endoglucanase D) (EC 3.2.1.4) (Carboxymethylcellulase D) (Cellulase D); Aspergillus turcosus; 4.083e-48 |
| XANPAGTX0501_010366-T1 | cl70 | AA9 | Upregulated in lichen | 0.59 | 71.09143 | 441 | IPR005103 Auxiliary Activity family 9 | AA9 | NA | Antimicrobial | 7A8V; Crystal structure of Polysaccharide monooxygenase from P.verruculosum; 3.565e-40 | 6H1Z; AFGH61B WILD-TYPE; 4.501e-37 | A0A093YIK5; Endo-beta-1,4-glucanase D (Endoglucanase D) (EC 3.2.1.4) (Carboxymethylcellulase D) (Cellulase D); Pseudogymnoascus sp. VKM F-3808; 8.832e-40 | A0A094A1Y7; Endo-beta-1,4-glucanase D (Endoglucanase D) (EC 3.2.1.4) (Carboxymethylcellulase D) (Cellulase D); Pseudogymnoascus sp. VKM F-4281 (FW-2241); 3.025e-39 |
| XANPAGTX0501_000361-T1 | cl71 | Chitin-binding. matching by small part | Non-DGE | 0.61 | 83.70659 | 211 | IPR001002 Chitin-binding, type 1;IPR036861 Endochitinase-like superfamily | CBM18, CE4 | NA | Antimicrobial | 9WGA; 2.2 ANGSTROMS RESOLUTION STRUCTURE ANALYSIS OF TWO REFINED N-ACETYLNEURAMINYLLACTOSE-WHEAT GERM AGGLUTININ ISOLECTIN COMPLEXES; 4.497e-09 | 4AML; CRYSTAL STRUCTURE OF WHEAT GERM AGGLUTININ ISOLECTIN 1 IN COMPLEX WITH GLYCOSYLURETHAN; 6.024e-08 | A0A3M7MIS9; Chitin binding; Pyrenophora seminiperda CCB06; 6.297e-29 | A0A6A5YEJ0; Carbohydrate-binding module family 18 protein; Saccharata proteae CBS 121410; 2.714e-25 |
| XANPAGTX0501_001885-T1 | cl71 | Chitin-binding. matching by small part | Non-DGE | 0.81 | 91.10910 | 577 | IPR001002 Chitin-binding, type 1;IPR006094 FAD linked oxidase, N-terminal;IPR012951 Berberine/berberine-like;IPR016166 FAD-binding domain, PCMH-type;IPR016167 FAD-binding, type PCMH, subdomain 1;IPR016169 FAD-binding, type PCMH, subdomain 2;IPR036318 FAD-binding, type PCMH-like superfamily;IPR036861 Endochitinase-like superfamily | AA7 | NA | Antimicrobial | 6YJO; Structure of FgChi7B; 3.163e-48 | 6Y0R; Chitooligosaccharide oxidase; 2.435e-47 | A0A6A6J9Y6; FAD-binding domain-containing protein; Westerdykella ornata; 1.209e-73 | A0A6P8AR07; Uncharacterized protein; Pyricularia grisea (Crabgrass-specific blast fungus) (Magnaporthe grisea); 9.974e-72 |
| XANPAGTX0501_002353-T1 | cl71 | Chitin-binding. matching by small part | Non-DGE | 0.77 | 83.01192 | 828 | IPR001002 Chitin-binding, type 1;IPR009880 Glyoxal oxidase, N-terminal;IPR011043 Galactose oxidase/kelch, beta-propeller;IPR013783 Immunoglobulin-like fold;IPR014756 Immunoglobulin E-set;IPR015202 Galactose oxidase-like, Early set domain;IPR036861 Endochitinase-like superfamily;IPR037293 Galactose oxidase, central domain superfamily | AA2, AA5 | NA | Antimicrobial | 2EIC; Crystal Structure of Galactose Oxidase mutant W290F; 3.114e-28 | 6RYX; Copper oxidase from Colletotrichum graminicola; 6.243e-28 | A0A6A5YBN8; Carbohydrate-binding module family 18; Aaosphaeria arxii CBS 175.79; 0 | A0A6A5S2H8; Carbohydrate-binding module family 18; Didymella exigua CBS 183.55; 0 |
| XANPAGTX0501_007748-T1 | cl71 | Chitin-binding. matching by small part | Non-DGE | 0.59 | 79.13302 | 557 | IPR001002 Chitin-binding, type 1;IPR002509 NodB homology domain;IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel;IPR018371 Chitin-binding, type 1, conserved site;IPR036861 Endochitinase-like superfamily | CBM18, CE4 | NA | Antimicrobial | 2IW0; Structure of the chitin deacetylase from the fungal pathogen Colletotrichum lindemuthianum; 9.071e-24 | 7BLY; Structure of the chitin deacetylase AngCDA from Aspergillus niger; 7.847e-21 | A0A2T7A6C8; Glycoside hydrolase/deacetylase; Tuber borchii (White truffle); 1.912e-53 | A0A1W5D7M5; Uncharacterized domain YCR061W, C-terminal; Lasallia pustulata; 2.188e-42 |
| XANPAGTX0501_009511-T1 | cl71 | Chitin-binding. matching by small part | Upregulated in lichen | 0.72 | 79.12778 | 405 | IPR000757 Glycoside hydrolase family 16;IPR001002 Chitin-binding, type 1;IPR013320 Concanavalin A-like lectin/glucanase domain superfamily;IPR036861 Endochitinase-like superfamily | GH16 | NA | Antimicrobial | 3AXD; The truncated Fibrobacter succinogenes 1,3-1,4-beta-D-glucanase V18Y/W203Y in apo-form; 1.371e-09 | 3HR9; The truncated Fibrobacter succinogenes 1,3-1,4-beta-D-glucanase F40I mutant; 2.009e-09 | A0A4U0U2S3; GH16 domain-containing protein; Salinomyces thailandica; 4.012e-23 | A0A066VPL4; GH16 domain-containing protein; Rhizoctonia solani AG-8 WAC10335; 6.797e-21 |
| XANPAGTX0501_001516-T1 | cl72 | Phosphatidylethanolamine-binding protein | Non-DGE | 0.71 | 77.76382 | 272 | IPR008914 Phosphatidylethanolamine-binding protein;IPR035810 Phosphatidylethanolamine-binding protein, eukaryotic;IPR036610 PEBP-like superfamily | NA | NA | Non-antimicrobial | 1WKP; Flowering locus t (ft) from arabidopsis thaliana; 3.856e-09 | 6IGJ; Crystal structure of FT condition 4; 1.152e-08 | A0A6A6CBM2; PEBP-like protein; Zasmidium cellare ATCC 36951; 1.859e-15 | A0A0S6XKH3; Uncharacterized protein; Fungal sp. (strain No.11243); 3.042e-15 |
| XANPAGTX0501_008387-T1 | cl72 | Phosphatidylethanolamine-binding protein | Non-DGE | 0.73 | 71.57141 | 283 | IPR008914 Phosphatidylethanolamine-binding protein;IPR035810 Phosphatidylethanolamine-binding protein, eukaryotic;IPR036610 PEBP-like superfamily | NA | I51 | Non-antimicrobial | 5TVD; Crystal structure of Tm16; 3.122e-14 | 6IGJ; Crystal structure of FT condition 4; 5.386e-14 | A0A3D8SPB3; PEBP-like protein; Coleophoma cylindrospora; 6.497e-22 | A0A2T7A9B5; Phosphatidylethanolamine-binding protein; Tuber borchii (White truffle); 1.518e-21 |
| XANPAGTX0501_000801-T1 | cl73 | No annotation | Non-DGE | 0.69 | 77.33250 | 224 | NA | NA | NA | Non-antimicrobial | NA | NA | A0A4U0XF57; Copper transport protein; Cryomyces minteri; 2.217e-18 | A0A0D2C558; Copper acquisition factor BIM1-like domain-containing protein; Exophiala oligosperma; 3.814e-17 |
| XANPAGTX0501_004004-T1 | cl73 | No annotation | Non-DGE | 0.74 | 83.51603 | 239 | NA | NA | NA | Non-antimicrobial | NA | NA | A0A0S7E3P3; Copper acquisition factor BIM1-like domain-containing protein; Aspergillus lentulus; 1.753e-28 | A0A0U1LWF8; Copper acquisition factor BIM1-like domain-containing protein; Talaromyces islandicus (Penicillium islandicum); 1.956e-28 |
| XANPAGTX0501_006291-T1 | cl74 | No annotation | Upregulated in lichen | 0.54 | 65.71913 | 160 | NA | NA | NA | Antimicrobial | NA | NA | NA | NA |
| XANPAGTX0501_010442-T1 | cl74 | No annotation | Upregulated in culture | 0.57 | 65.98594 | 160 | NA | NA | NA | Antimicrobial | 3PDG; Structures of Clostridium thermocellum CbhA fibronectin(III)-like modules; 0.0005652 | NA | NA | NA |
| XANPAGTX0501_003237-T1 | cl75 | Endonuclease/exonuclease/phosphatase | Non-DGE | 0.86 | 90.48891 | 531 | IPR036691 Endonuclease/exonuclease/phosphatase superfamily | NA | NA | Non-antimicrobial | NA | NA | A0A1V8V0E0; Endonuclease/exonuclease/phosphatase domain-containing protein; Rachicladosporium sp. CCFEE 5018; 3.478e-69 | A0A0N1H0H2; Endonuclease/exonuclease/phosphatase domain-containing protein; Phialophora attinorum; 6.712e-58 |
| XANPAGTX0501_006312-T1 | cl75 | Endonuclease/exonuclease/phosphatase | Non-DGE | 0.92 | 95.35402 | 617 | IPR036691 Endonuclease/exonuclease/phosphatase superfamily | NA | NA | Antimicrobial | 3MPR; Crystal Structure of endonuclease/exonuclease/phosphatase family protein from Bacteroides thetaiotaomicron, Northeast Structural Genomics Consortium Target BtR318A; 2.66e-12 | 5J3Z; Crystal structure of m2hTDP2-CAT in complex with a small molecule inhibitor; 1.604e-10 | A0A2W1HX62; deleted; ; 5.723e-77 | A0A513ZSD8; Endonuclease/exonuclease/phosphatase family protein; Cordyceps militaris (Caterpillar fungus) (Clavaria militaris); 2.75e-62 |
| XANPAGTX0501_006272-T1 | cl76 | Aminopeptidase M28 | Non-DGE | 0.91 | 93.62283 | 374 | IPR007484 Peptidase M28 | NA | M28E | Non-antimicrobial | 6ICA; The crystal structure of Legionella pneumophila LapA aminopeptidase; 1.829e-25 | 6ICA; The crystal structure of Legionella pneumophila LapA aminopeptidase; 3.471e-25 | A0A0B7K3C1; Peptide hydrolase (EC 3.4.-.-); Bionectria ochroleuca (Gliocladium roseum); 3.858e-43 | A0A0F4Z9C9; Peptide hydrolase (EC 3.4.-.-); Thielaviopsis punctulata; 5.039e-43 |
| XANPAGTX0501_006687-T1 | cl76 | Aminopeptidase M28 | Non-DGE | 0.89 | 92.02210 | 386 | IPR007484 Peptidase M28 | NA | M28E | Non-antimicrobial | 6ICA; The crystal structure of Legionella pneumophila LapA aminopeptidase; 1.184e-28 | 6ICA; The crystal structure of Legionella pneumophila LapA aminopeptidase; 2.371e-28 | A0A094DR96; Peptide hydrolase (EC 3.4.-.-); Pseudogymnoascus sp. VKM F-4515 (FW-2607); 4.826e-60 | A0A6G1JZI7; Peptide hydrolase (EC 3.4.-.-); Pleomassaria siparia CBS 279.74; 6.444e-60 |
| XANPAGTX0501_006220-T1 | cl77 | Patulin synthase | Non-DGE | 0.83 | 84.85463 | 367 | IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal;IPR036188 FAD/NAD(P)-binding domain superfamily | AA3 | NA | Non-antimicrobial | 8BXL; Patulin Synthase from Penicillium expansum; 2.047e-30 | 6YRX; Low-dose crystal structure of FAP at room temperature; 5.39e-19 | A0A0N1HAN7; Versicolorin B synthase; Phialophora attinorum; 2.268e-35 | A0A0U1LYJ0; Versicolorin B synthase; Talaromyces islandicus (Penicillium islandicum); 4.409e-35 |
| XANPAGTX0501_009862-T1 | cl77 | Patulin synthase | Non-DGE | 0.84 | 84.50499 | 391 | IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal;IPR036188 FAD/NAD(P)-binding domain superfamily | AA3 | NA | Non-antimicrobial | 8BXL; Patulin Synthase from Penicillium expansum; 2.617e-36 | 5OC1; Crystal structure of aryl-alcohol oxidase from Pleurotus eryngii in complex with p-anisic acid; 3.111e-25 | A0A6A6I6J7; GMC oxidoreductase; Trematosphaeria pertusa; 6.552e-45 | A0A5M8PRZ8; Versicolorin b synthase; Lasallia pustulata; 3.558e-44 |
| XANPAGTX0501_001675-T1 | cl78 | Cholin/aryl-alcohol oxidase | Non-DGE | 0.92 | 92.20677 | 619 | IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal;IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal;IPR012132 Glucose-methanol-choline oxidoreductase;IPR036188 FAD/NAD(P)-binding domain superfamily | AA3 | NA | Antimicrobial | 3FIM; Crystal structure of aryl-alcohol-oxidase from Pleurotus eryingii; 1.624e-51 | 7R33; Difference-refined structure of fatty acid photodecarboxylase 20 ps following 400-nm laser irradiation of the dark-state determined by SFX; 2.145e-46 | A0A6A7ARW9; GMC oxidoreductase; Plenodomus tracheiphilus IPT5; 2.523e-91 | A0A6A4HEV5; Alcohol oxidase; Gymnopus androsaceus JB14; 1.386e-74 |
| XANPAGTX0501_002462-T1 | cl78 | Cholin/aryl-alcohol oxidase | Non-DGE | 0.92 | 93.55743 | 612 | IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal;IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal;IPR012132 Glucose-methanol-choline oxidoreductase;IPR036188 FAD/NAD(P)-binding domain superfamily | AA3 | NA | Non-antimicrobial | 7R33; Difference-refined structure of fatty acid photodecarboxylase 20 ps following 400-nm laser irradiation of the dark-state determined by SFX; 3.686e-53 | 6YS1; Crystal structure of FAP R451K mutant in the dark at 100K; 1.239e-51 | A0A4Z1J5Y0; Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein; Botrytis elliptica; 3.656e-98 | A0A6A6RAV7; Alcohol oxidase; Lophium mytilinum; 1.776e-87 |
| XANPAGTX0501_002692-T1 | cl78 | Cholin/aryl-alcohol oxidase | Non-DGE | 0.92 | 91.25600 | 635 | IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal;IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal;IPR012132 Glucose-methanol-choline oxidoreductase;IPR036188 FAD/NAD(P)-binding domain superfamily | AA3 | NA | Non-antimicrobial | 3LJP; Crystal structure of choline oxidase V464A mutant; 2.471e-52 | 2JBV; Crystal structure of choline oxidase reveals insights into the catalytic mechanism; 2.162e-51 | A0A1S8B712; Choline dehydrogenase; Diplodia seriata; 5.274e-90 | R1FVG2; Putative gmc oxidoreductase protein; Botryosphaeria parva (strain UCR-NP2) (Grapevine canker fungus) (Neofusicoccum parvum); 3.386e-89 |
| XANPAGTX0501_002963-T1 | cl78 | Cholin/aryl-alcohol oxidase | Non-DGE | 0.61 | 64.93838 | 1156 | IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal;IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal;IPR036188 FAD/NAD(P)-binding domain superfamily | AA3 | NA | Below pLDDT threshold | 6O9N; Structural insights on a new fungal aryl-alcohol oxidase; 4.054e-58 | 7VKD; Reduced enzyme of FAD-dpendent Glucose Dehydrogenase at pH6.5; 4.231e-57 | A0A5M8PKB2; Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein; Lasallia pustulata; 0 | A0A1W5CT22; Glucose-methanol-choline oxidoreductase, N-terminal; Lasallia pustulata; 0 |
| XANPAGTX0501_003140-T1 | cl78 | Cholin/aryl-alcohol oxidase | Upregulated in culture | 0.87 | 87.53881 | 695 | IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal;IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal;IPR012132 Glucose-methanol-choline oxidoreductase;IPR036188 FAD/NAD(P)-binding domain superfamily | AA3 | NA | Non-antimicrobial | 8BXL; Patulin Synthase from Penicillium expansum; 3.439e-88 | 5OC1; Crystal structure of aryl-alcohol oxidase from Pleurotus eryngii in complex with p-anisic acid; 1.932e-53 | A0A6V8H8J1; Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein; Talaromyces pinophilus (Penicillium pinophilum); 1.158e-102 | A0A420RG73; Versicolorin B synthase; Fusarium oxysporum (Fusarium vascular wilt); 6.15e-86 |
| XANPAGTX0501_005244-T1 | cl78 | Cholin/aryl-alcohol oxidase | Upregulated in culture | 0.92 | 93.05731 | 629 | IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal;IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal;IPR012132 Glucose-methanol-choline oxidoreductase;IPR036188 FAD/NAD(P)-binding domain superfamily | AA3 | NA | Non-antimicrobial | 4YNT; Crystal structure of Aspergillus flavus FAD glucose dehydrogenase; 1.274e-54 | 5OC1; Crystal structure of aryl-alcohol oxidase from Pleurotus eryngii in complex with p-anisic acid; 2.585e-53 | A0A084RWW1; deleted; ; 5.607e-75 | A0A2S6BXM5; Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein; Cercospora berteroae; 3.165e-69 |
| XANPAGTX0501_009758-T1 | cl78 | Cholin/aryl-alcohol oxidase | Non-DGE | 0.9 | 89.26037 | 595 | IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal;IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal;IPR012132 Glucose-methanol-choline oxidoreductase;IPR036188 FAD/NAD(P)-binding domain superfamily | AA3 | NA | Antimicrobial | 5OC1; Crystal structure of aryl-alcohol oxidase from Pleurotus eryngii in complex with p-anisic acid; 2.842e-51 | 3FIM; Crystal structure of aryl-alcohol-oxidase from Pleurotus eryingii; 5.959e-49 | A0A317VTY9; Alcohol oxidase; Aspergillus sclerotioniger CBS 115572; 3.092e-71 | A0A6V8H8J1; Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein; Talaromyces pinophilus (Penicillium pinophilum); 1.757e-69 |
| XANPAGTX0501_007624-T1 | cl79 | No annotation | Non-DGE | 0.6 | 62.86249 | 289 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_008290-T1 | cl79 | No annotation | Non-DGE | 0.73 | 74.65504 | 236 | NA | NA | NA | Antimicrobial | NA | NA | A0A136J8L8; Cyanovirin-N domain-containing protein; Microdochium bolleyi; 0.0002174 | D4AMW3; Uncharacterized secreted protein ARB_05566; Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton mentagrophytes); 0.0009542 |
| XANPAGTX0501_009606-T1 | cl80 | Gamma-crystallin-like | Upregulated in lichen | 0.6 | 79.86218 | 142 | NA | NA | NA | Non-antimicrobial | 1HDF; Evolution of the eye lens beta-gamma-crystallin domain fold; 1.302e-05 | 3SNZ; Crystal structure of a mutant W39D of a betagamma-crystallin domain from Clostridium beijerinckii; 0.0001275 | A0A1B8G710; Uncharacterized protein; Pseudogymnoascus verrucosus; 2.272e-10 | A0A4T0W2D3; Uncharacterized protein; Colletotrichum higginsianum; 8.437e-10 |
| XANPAGTX0501_009649-T1 | cl80 | Gamma-crystallin-like | Non-DGE | 0.73 | 84.10992 | 125 | NA | NA | NA | Non-antimicrobial | NA | NA | A0A1L9T545; Uncharacterized protein; Aspergillus sydowii CBS 593.65; 1.401e-08 | A0A1Y2W4B1; Uncharacterized protein; Hypoxylon sp. CI-4A; 2.365e-06 |
| XANPAGTX0501_000740-T1 | cl81 | Aspartic peptidase | Non-DGE | 0.7 | 68.28128 | 592 | IPR001461 Aspartic peptidase A1 family;IPR021109 Aspartic peptidase domain superfamily;IPR033121 Peptidase family A1 domain;IPR033876 Secreted aspartic endopeptidase | NA | A01A | Antimicrobial | 7AGB; Protease Sapp1p from Candida parapsilosis in complex with KB70; 2.331e-34 | 1J71; Structure of the extracellular aspartic proteinase from Candida tropicalis yeast.; 4.586e-34 | A0A0D2APD0; Peptidase A1 domain-containing protein; Verruconis gallopava; 5.708e-42 | A0A842Z296; deleted; ; 4.08e-36 |
| XANPAGTX0501_000747-T1 | cl81 | Aspartic peptidase | Non-DGE | 0.83 | 80.26111 | 468 | IPR001461 Aspartic peptidase A1 family;IPR001969 Aspartic peptidase, active site;IPR021109 Aspartic peptidase domain superfamily;IPR033121 Peptidase family A1 domain;IPR033876 Secreted aspartic endopeptidase | NA | A01A | Antimicrobial | 1J71; Structure of the extracellular aspartic proteinase from Candida tropicalis yeast.; 2.402e-36 | 2QZW; Secreted aspartic proteinase (Sap) 1 from Candida albicans; 7.453e-36 | A0A2G7FL77; Aspartic-type endopeptidase opsB; Aspergillus arachidicola; 5.992e-42 | A0A225APP5; Putative aspartic-type endopeptidase opsB; Talaromyces atroroseus; 1.968e-41 |
| XANPAGTX0501_003097-T1 | cl81 | Aspartic peptidase | Non-DGE | 0.81 | 78.76526 | 392 | IPR001461 Aspartic peptidase A1 family;IPR021109 Aspartic peptidase domain superfamily;IPR033121 Peptidase family A1 domain | NA | A01A | Antimicrobial | 6RSV; Endothiapepsin in complex with 017; 1.597e-27 | 4YCY; Endothiapepsin in complex with fragment 218; 2.192e-26 | A0A0D1XMT6; Peptidase A1 domain-containing protein; Verruconis gallopava; 4.332e-27 | A0A2B7YGS7; Peptidase A1 domain-containing protein; Polytolypa hystricis UAMH7299; 9.718e-26 |
| XANPAGTX0501_003124-T1 | cl81 | Aspartic peptidase | Upregulated in lichen | 0.84 | 83.03405 | 440 | IPR001461 Aspartic peptidase A1 family;IPR001969 Aspartic peptidase, active site;IPR021109 Aspartic peptidase domain superfamily;IPR033121 Peptidase family A1 domain;IPR034164 Pepsin-like domain | NA | A01A | Non-antimicrobial | 1UH8; Crystal structure of rhizopuspepsin at pH 8.0; 2.348e-23 | 5APR; STRUCTURES OF COMPLEXES OF RHIZOPUSPEPSIN WITH PEPSTATIN AND OTHER STATINE-CONTAINING INHIBITORS; 5.573e-23 | A0A0G2EMW1; Putative aspartic-type; Phaeomoniella chlamydospora; 3.931e-42 | A0A4S8ZDK6; Acid protease; Aureobasidium pullulans (Black yeast) (Pullularia pullulans); 1.222e-41 |
| XANPAGTX0501_003693-T1 | cl81 | Aspartic peptidase | Non-DGE | 0.84 | 83.69188 | 399 | IPR001461 Aspartic peptidase A1 family;IPR001969 Aspartic peptidase, active site;IPR021109 Aspartic peptidase domain superfamily;IPR033121 Peptidase family A1 domain | NA | A01A | Antimicrobial | 1FMX; STRUCTURE OF NATIVE PROTEINASE A IN THE SPACE GROUP P21; 8.943e-50 | 1FMU; STRUCTURE OF NATIVE PROTEINASE A IN P3221 SPACE GROUP.; 8.586e-49 | A0A232M6J5; Peptidase A1 domain-containing protein; Elaphomyces granulatus; 2.51e-56 | F8MUL2; Aspartic proteinase, pepstatin-sensitive; Neurospora tetrasperma (strain FGSC 2508 / ATCC MYA-4615 / P0657); 5.627e-55 |
| XANPAGTX0501_004043-T1 | cl81 | Aspartic peptidase | Non-DGE | 0.82 | 82.46504 | 425 | IPR001461 Aspartic peptidase A1 family;IPR001969 Aspartic peptidase, active site;IPR021109 Aspartic peptidase domain superfamily;IPR033121 Peptidase family A1 domain;IPR034163 Aspergillopepsin-like catalytic domain | NA | A01A | Non-antimicrobial | 2WEC; ACID PROTEINASE (PENICILLOPEPSIN) (E.C.3.4.23.20) COMPLEX WITH PHOSPHONATE INHIBITOR: METHYL(2S)-[1-(((N-(1-NAPHTHALENEACETYL))-L-VALYL)AMINOMETHYL)HYDROXY PHOSPHINYLOXY]-3-PHENYLPROPANOATE, SODIUM SALT; 6.328e-42 | 4YCT; Endothiapepsin in complex with fragment 216; 2.059e-41 | A0A507AUA0; Peptidase A1 domain-containing protein; Thyridium curvatum; 9.039e-46 | A0A165HBS6; Putative extracellular aspartic endopeptidase; Xylona heveae (strain CBS 132557 / TC161); 2.099e-45 |
| XANPAGTX0501_007515-T1 | cl81 | Aspartic peptidase | Upregulated in lichen | 0.82 | 86.80152 | 396 | IPR001461 Aspartic peptidase A1 family;IPR001969 Aspartic peptidase, active site;IPR021109 Aspartic peptidase domain superfamily;IPR033121 Peptidase family A1 domain;IPR034163 Aspergillopepsin-like catalytic domain | NA | A01A | Antimicrobial | 4Y48; Endothiapepsin in complex with fragment B50; 1.001e-47 | 6RSV; Endothiapepsin in complex with 017; 1.001e-47 | A0A1Q8RB75; Endothiapepsin; Colletotrichum chlorophyti; 3.9e-53 | A0A4S9M350; Peptidase A1 domain-containing protein; Aureobasidium pullulans (Black yeast) (Pullularia pullulans); 1.653e-52 |
| XANPAGTX0501_008754-T1 | cl81 | Aspartic peptidase | Non-DGE | 0.8 | 78.96484 | 483 | IPR001461 Aspartic peptidase A1 family;IPR001969 Aspartic peptidase, active site;IPR021109 Aspartic peptidase domain superfamily;IPR033121 Peptidase family A1 domain;IPR033876 Secreted aspartic endopeptidase | NA | A01A | Antimicrobial | 7AGB; Protease Sapp1p from Candida parapsilosis in complex with KB70; 1.616e-35 | 3FV3; Secreted aspartic protease 1 from Candida parapsilosis in complex with pepstatin A; 7.405e-34 | A0A1J9QJZ9; Aspartic-type endopeptidase; Diplodia corticola; 1.179e-47 | A1C4K0; Yapsin; Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107); 2.616e-44 |
| XANPAGTX0501_005657-T1 | cl82 | No annotation | Non-DGE | 0.57 | 57.60056 | 482 | NA | NA | NA | Below pLDDT threshold | NA | NA | A0A5M8Q482; Uncharacterized protein; Lasallia pustulata; 2.576e-22 | A0A2K9YE87; Uncharacterized protein; Cladonia uncialis subsp. uncialis; 2.496e-20 |
| XANPAGTX0501_006967-T1 | cl82 | No annotation | Upregulated in lichen | 0.6 | 63.78815 | 504 | NA | NA | NA | Below pLDDT threshold | NA | NA | A0A2K9YE87; Uncharacterized protein; Cladonia uncialis subsp. uncialis; 4.59e-24 | A0A5M8Q482; Uncharacterized protein; Lasallia pustulata; 1.422e-23 |
| XANPAGTX0501_007280-T1 | cl82 | No annotation | Upregulated in lichen | 0.63 | 59.71566 | 401 | NA | NA | NA | Below pLDDT threshold | NA | NA | A0A2K9YE87; Uncharacterized protein; Cladonia uncialis subsp. uncialis; 5.734e-18 | A0A5M8Q482; Uncharacterized protein; Lasallia pustulata; 2.469e-17 |
| XANPAGTX0501_000106-T1 | cl83 | Papain inbitor | Non-DGE | 0.72 | 67.79074 | 202 | IPR036908 RlpA-like domain superfamily | NA | NA | Non-antimicrobial | 3X2L; X-ray structure of PcCel45A apo form at 95K.; 2.454e-09 | 3X2H; X-ray structure of PcCel45A N92D with cellopentaose at 95K.; 5.375e-09 | A0A0E0F0C5; Expansin; Oryza meridionalis; 0.0005526 | A0A6P6U5N5; Expansin-like B1 isoform X2; Coffea arabica (Arabian coffee); 0.0005526 |
| XANPAGTX0501_001015-T1 | cl83 | Papain inbitor | Upregulated in lichen | 0.79 | 88.99895 | 143 | IPR036908 RlpA-like domain superfamily | NA | NA | Non-antimicrobial | 5NTB; Streptomyces papain inhibitor (SPI); 1.228e-09 | 4AVR; Crystal structure of the hypothetical protein Pa4485 from Pseudomonas aeruginosa; 5.917e-07 | S3CYI0; Barwin-like endoglucanase; Glarea lozoyensis (strain ATCC 20868 / MF5171); 4.104e-19 | A0A0C3H1Y4; RlpA-like protein double-psi beta-barrel domain-containing protein; Oidiodendron maius (strain Zn); 1.522e-18 |
| XANPAGTX0501_005809-T1 | cl83 | Papain inbitor | Non-DGE | 0.81 | 90.24906 | 128 | IPR001153 Barwin domain;IPR036908 RlpA-like domain superfamily | NA | NA | Antimicrobial | 5NTB; Streptomyces papain inhibitor (SPI); 3.868e-10 | 7WVR; Crystal structure of Talaromyces leycettanus JCM12802 expansin; 5.306e-07 | A0A6G1HT02; RlpA-like protein double-psi beta-barrel domain-containing protein; Trichodelitschia bisporula; 1.825e-13 | A0A367J2H3; RlpA-like protein double-psi beta-barrel domain-containing protein; Rhizopus stolonifer (Rhizopus nigricans); 7.186e-12 |
| XANPAGTX0501_006194-T1 | cl83 | Papain inbitor | Upregulated in lichen | 0.79 | 88.48266 | 154 | IPR036908 RlpA-like domain superfamily | NA | NA | Antimicrobial | 3X2P; Neutron and X-ray joint refined structure of PcCel45A with cellopentaose at 298K.; 1.055e-10 | 3X2H; X-ray structure of PcCel45A N92D with cellopentaose at 95K.; 1.122e-10 | A0A4U0URI0; CBM1 domain-containing protein; Friedmanniomyces endolithicus; 4.21e-14 | A0A3M7AHM8; CBM1 domain-containing protein; Hortaea werneckii; 1.959e-13 |
| XANPAGTX0501_009885-T1 | cl83 | Papain inbitor | Non-DGE | 0.69 | 80.85400 | 190 | IPR009009 RlpA-like protein, double-psi beta-barrel domain;IPR036908 RlpA-like domain superfamily | NA | NA | Non-antimicrobial | 5NTB; Streptomyces papain inhibitor (SPI); 4.147e-10 | 7WVR; Crystal structure of Talaromyces leycettanus JCM12802 expansin; 7.484e-09 | A0A1D1VXJ0; Expansin-like EG45 domain-containing protein; Ramazzottius varieornatus (Water bear) (Tardigrade); 6.686e-14 | A0A1R1Y825; Papain inhibitor; Smittium culicis; 1.948e-13 |
| XANPAGTX0501_000099-T1 | not in cluster | NA | Non-DGE | 0.88 | 90.33257 | 385 | IPR009486 Purine nucleoside permease | NA | NA | Non-antimicrobial | 3EEI; Crystal structure of 5’-methylthioadenosine/S-adenosylhomocysteine nucleosidase from neisseria meningitidis in complex with methylthio-immucillin-A; 1.541e-12 | 1Z5O; Crystal structure of MTA/AdoHcy nucleosidase Asp197Asn mutant complexed with 5’-methylthioadenosine; 1.638e-12 | A0A094HNX8; Helicase ATP-binding domain-containing protein; Pseudogymnoascus sp. VKM F-4519 (FW-2642); 2.911e-55 | A0A1V6QYV1; Purine nucleoside permease; Penicillium solitum; 2.707e-53 |
| XANPAGTX0501_000467-T1 | not in cluster | NA | Upregulated in lichen | 0.52 | 52.38919 | 161 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_000626-T1 | not in cluster | NA | Non-DGE | 0.5 | 64.90024 | 328 | IPR008972 Cupredoxin | NA | NA | Below pLDDT threshold | 3BQV; Crystal Structure of the double mutant D44A D45A Plastocyanin from Phormidium laminosum; 6.543e-08 | 4R0O; Crystal structure of PEGylated plastocyanin at 4.2 A resolution; 8.918e-08 | A0A2T3AXE3; Phytocyanin domain-containing protein; Amorphotheca resinae ATCC 22711; 3.987e-22 | A0A6A6GXA8; Phytocyanin domain-containing protein; Viridothelium virens; 6.475e-21 |
| XANPAGTX0501_000633-T1 | not in cluster | NA | Non-DGE | 0.68 | 70.34727 | 326 | IPR001223 Glycoside hydrolase family 18, catalytic domain;IPR011583 Chitinase II;IPR017853 Glycoside hydrolase superfamily | GH18 | NA | Non-antimicrobial | 1E6N; Chitinase B from Serratia marcescens inactive mutant E144Q in complex with N-acetylglucosamine-pentamer; 5.632e-13 | 4Z2H; Serratia marcescens Chitinase B complexed with macrolide inhibitor 29; 7.292e-13 | A0A6A6VMZ0; chitinase (EC 3.2.1.14); Sporormia fimetaria CBS 119925; 2.347e-28 | A0A1W2TM45; chitinase (EC 3.2.1.14); Rosellinia necatrix (White root-rot fungus); 1.341e-27 |
| XANPAGTX0501_000833-T1 | not in cluster | NA | Non-DGE | 0.81 | 85.55586 | 244 | IPR012349 FMN-binding split barrel | NA | NA | Non-antimicrobial | 1XHN; The crystal structure of Cellular Repressor of E1A-stimulated Genes (CREG); 8.145e-11 | 2HQ9; Crystal structure of a fad-binding protein (mll6688) from mesorhizobium loti at 1.95 A resolution; 9.275e-06 | A0A7C8IBI1; Pyridoxamine 5’-phosphate oxidase-domain-containing protein; Massariosphaeria phaeospora; 7.769e-29 | A0A545A0I8; deleted; ; 6.809e-27 |
| XANPAGTX0501_001028-T1 | not in cluster | NA | Non-DGE | 0.63 | 66.45818 | 556 | IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal;IPR036188 FAD/NAD(P)-binding domain superfamily | AA3 | NA | Antimicrobial | 1KDG; Crystal structure of the flavin domain of cellobiose dehydrogenase; 3.678e-33 | 4QI7; Cellobiose dehydrogenase from Neurospora crassa, NcCDH; 4.108e-32 | L8G156; Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein; Pseudogymnoascus destructans (strain ATCC MYA-4855 / 20631-21) (Bat white-nose syndrome fungus) (Geomyces destructans); 2.656e-43 | M3D149; FAD/NAD(P)-binding domain-containing protein; Sphaerulina musiva (strain SO2202) (Poplar stem canker fungus) (Septoria musiva); 7.147e-43 |
| XANPAGTX0501_001083-T1 | not in cluster | NA | Non-DGE | 0.64 | 70.77810 | 601 | IPR007266 Endoplasmic reticulum oxidoreductin 1;IPR037192 ERO1-like superfamily | NA | NA | Non-antimicrobial | 1RQ1; Structure of Ero1p, Source of Disulfide Bonds for Oxidative Protein Folding in the Cell; 2.83e-18 | 3M31; Structure of the C150A/C295A mutant of S. cerevisiae Ero1p; 3.257e-18 | A0A4S8MEM9; Endoplasmic oxidoreductin; Dendrothele bispora (strain CBS 962.96); 7.411e-25 | A0A1Y1VH03; Endoplasmic oxidoreductin; Piromyces finnis; 9.816e-25 |
| XANPAGTX0501_001094-T1 | not in cluster | NA | Non-DGE | 0.51 | 72.94346 | 463 | IPR013766 Thioredoxin domain;IPR017937 Thioredoxin, conserved site;IPR036249 Thioredoxin-like superfamily | NA | NA | Non-antimicrobial | 3ED3; Crystal Structure of the Yeast Dithiol/Disulfide Oxidoreductase Mpd1p; 5.614e-22 | 5GU6; Crystal structure of Human ERp44 form I; 3.746e-16 | A0A1W5DAQ3; Disulfide isomerase; Lasallia pustulata; 4.161e-49 | A0A1R3RS37; Thioredoxin domain-containing protein; Aspergillus carbonarius (strain ITEM 5010); 7.582e-47 |
| XANPAGTX0501_001104-T1 | not in cluster | NA | Non-DGE | 0.72 | 76.57498 | 466 | IPR018805 Cell wall protein YJL171C/Tos1, C-terminal;IPR018807 Cell wall protein YJL171C/Tos1, N-terminal | NA | NA | Antimicrobial | NA | NA | A0A0G2I0T9; glucan endo-1,3-beta-D-glucosidase (EC 3.2.1.39); Emmonsia crescens UAMH 3008; 7.324e-44 | W9YCH4; glucan endo-1,3-beta-D-glucosidase (EC 3.2.1.39); Capronia epimyces CBS 606.96; 1.256e-41 |
| XANPAGTX0501_001259-T1 | not in cluster | NA | Non-DGE | 0.81 | 82.29719 | 352 | IPR022751 Alpha-mannosyltransferase;IPR029044 Nucleotide-diphospho-sugar transferases | GT71 | NA | Antimicrobial | 4UEG; Crystal structure of human glycogenin-2 catalytic domain; 0.0008143 | NA | A0A0D8JT77; Alpha-1,3-mannosyltransferase; Coccidioides immitis (strain RS) (Valley fever fungus); 2.444e-32 | A0A072PC86; Alpha-1,3-mannosyltransferase; Exophiala aquamarina CBS 119918; 4.853e-32 |
| XANPAGTX0501_001264-T1 | not in cluster | NA | Non-DGE | 0.9 | 91.90525 | 577 | IPR001362 Glycoside hydrolase, family 32;IPR013148 Glycosyl hydrolase family 32, N-terminal;IPR013189 Glycosyl hydrolase family 32, C-terminal;IPR013320 Concanavalin A-like lectin/glucanase domain superfamily;IPR018053 Glycoside hydrolase, family 32, active site;IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily | GH32 | NA | Non-antimicrobial | 8BEQ; Structure of fructofuranosidase from Rhodotorula dairenensis; 6.094e-67 | 8BEU; Structure of D188A-fructofuranosidase from Rhodotorula dairenensis in complex with raffinose; 2.911e-66 | A0A067TBQ3; Glycosyl hydrolase family 32 N-terminal domain-containing protein; Galerina marginata (strain CBS 339.88); 8.249e-79 | A0A4T0B7E3; Glycosyl hydrolase family 32 N-terminal domain-containing protein; Aureobasidium pullulans (Black yeast) (Pullularia pullulans); 8.913e-76 |
| XANPAGTX0501_001663-T1 | not in cluster | NA | Non-DGE | 0.66 | 66.74461 | 271 | IPR000111 Glycoside hydrolase family 27/36, conserved site;IPR002241 Glycoside hydrolase, family 27;IPR013785 Aldolase-type TIM barrel;IPR017853 Glycoside hydrolase superfamily | NA | NA | Non-antimicrobial | 3A5V; Crystal structure of alpha-galactosidase I from Mortierella vinacea; 2.572e-24 | 3LXC; Interconversion of Human Lysosomal Enzyme Specificities; 4.085e-20 | A0A0F7STC2; Alpha-galactosidase (EC 3.2.1.22) (Melibiase); Phaffia rhodozyma (Yeast) (Xanthophyllomyces dendrorhous); 2.926e-23 | A0A2N5US34; Alpha-galactosidase (EC 3.2.1.22) (Melibiase); Puccinia coronata f. sp. avenae; 7.35e-23 |
| XANPAGTX0501_001758-T1 | not in cluster | NA | Non-DGE | 0.82 | 86.77719 | 327 | IPR002472 Palmitoyl protein thioesterase;IPR029058 Alpha/Beta hydrolase fold | NA | NA | Non-antimicrobial | 3GRO; Human palmitoyl-protein thioesterase 1; 1.497e-32 | 1EXW; CRYSTAL STRUCTURE OF PALMITOYL PROTEIN THIOESTERASE 1 COMPLEXED WITH HEXADECYLSULFONYL FLUORIDE; 4.429e-32 | A0A3D8RZZ4; Palmitoyl-protein thioesterase 1 (EC 3.1.2.22) (Palmitoyl-protein hydrolase 1); Coleophoma cylindrospora; 1.619e-47 | A0A136IMG9; Palmitoyl-protein thioesterase 1 (EC 3.1.2.22) (Palmitoyl-protein hydrolase 1); Microdochium bolleyi; 1.828e-46 |
| XANPAGTX0501_001815-T1 | not in cluster | NA | Non-DGE | 0.85 | 85.35372 | 457 | IPR003961 Fibronectin type III;IPR007484 Peptidase M28;IPR036116 Fibronectin type III superfamily | NA | M28E | Non-antimicrobial | 3B3C; Crystal structure of the M180A mutant of the aminopeptidase from Vibrio proteolyticus in complex with leucine phosphonic acid; 2.769e-15 | 2ANP; Functional Glutamate 151 to Histidine mutant of the aminopeptidase from Aeromonas Proteolytica.; 2.769e-15 | A0A5C3Q954; Peptide hydrolase (EC 3.4.-.-); Pterula gracilis; 3.334e-60 | A0A0C9VRY9; Peptide hydrolase (EC 3.4.-.-); Sphaerobolus stellatus (strain SS14); 2.84e-59 |
| XANPAGTX0501_002007-T1 | not in cluster | NA | Non-DGE | 0.61 | 71.28474 | 817 | NA | NA | NA | Non-antimicrobial | 8IC1; endo-alpha-D-arabinanase EndoMA1 D51N mutant from Microbacterium arabinogalactanolyticum in complex with arabinooligosaccharides; 3.989e-10 | NA | A0A1W5CV57; Apple domain-containing protein; Lasallia pustulata; 8.633e-83 | U1GB34; Apple domain-containing protein; Endocarpon pusillum (strain Z07020 / HMAS-L-300199) (Lichen-forming fungus); 8.167e-66 |
| XANPAGTX0501_002144-T1 | not in cluster | NA | Non-DGE | 0.94 | 93.64874 | 886 | IPR001764 Glycoside hydrolase, family 3, N-terminal;IPR002772 Glycoside hydrolase family 3 C-terminal domain;IPR013783 Immunoglobulin-like fold;IPR017853 Glycoside hydrolase superfamily;IPR019800 Glycoside hydrolase, family 3, active site;IPR026891 Fibronectin type III-like domain;IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily;IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily | GH3 | NA | Antimicrobial | 5FJJ; Three-dimensional structures of two heavily N-glycosylated Aspergillus sp. Family GH3 beta-D-glucosidases; 0 | 4IIH; Crystal structure of beta-glucosidase 1 from Aspergillus aculeatus in complex with thiocellobiose; 0 | A0A5N5CY28; beta-glucosidase (EC 3.2.1.21); Lasiodiplodia theobromae; 0 | Q0CTD7; Probable beta-glucosidase A (EC 3.2.1.21) (Beta-D-glucoside glucohydrolase A) (Cellobiase A) (Gentiobiase A); Aspergillus terreus (strain NIH 2624 / FGSC A1156); 0 |
| XANPAGTX0501_002316-T1 | not in cluster | NA | Non-DGE | 0.66 | 70.70526 | 538 | NA | NA | NA | Non-antimicrobial | 4QRK; Crystal structure of a putative cell adhesion protein (CLOSPO_03726) from Clostridium sporogenes ATCC 15579 at 1.95 A resolution; 9.468e-06 | NA | A0A6A6Y9H6; Adhesin domain-containing protein; Mytilinidion resinicola; 6.364e-23 | A0A4Z1NZS1; Adhesin domain-containing protein; Venturia nashicola; 7.993e-22 |
| XANPAGTX0501_002376-T1 | not in cluster | NA | Non-DGE | 0.91 | 91.82710 | 822 | IPR014870 Domain of unknown function DUF1793;IPR032514 Domain of unknown function DUF4965;IPR033433 Domain of unknown function DUF5127 | NA | NA | Non-antimicrobial | 5O0S; Crystal structure of txGH116 (beta-glucosidase from Thermoanaerobacterium xylolyticum) in complex with unreacted beta Cyclophellitol Cyclosulfate probe ME711; 8.68e-22 | 5FJS; Bacterial beta-glucosidase reveals the structural and functional basis of genetic defects in human glucocerebrosidase 2 (GBA2); 8.42e-19 | A0A6A6GM90; Glutaminase A; Elsinoe ampelina; 0 | A0A0U1LR85; UPF0202 protein; Talaromyces islandicus (Penicillium islandicum); 0 |
| XANPAGTX0501_002396-T1 | not in cluster | NA | Non-DGE | 0.88 | 90.18261 | 440 | IPR000834 Peptidase M14, carboxypeptidase A;IPR003146 Carboxypeptidase, activation peptide;IPR036990 Metallocarboxypeptidase-like, propeptide | NA | M14A | Non-antimicrobial | 4UF4; NA; 5.797e-45 | 5OM9; Crystal structure of the human CARBOXYPEPTIDASE A1 in complex with a thiirane mechanism-based inhibitor; 1.045e-44 | A0A0M9VUM1; Metallocarboxypeptidase A; Escovopsis weberi; 1.996e-58 | A0A430LPP9; Peptidase M14 carboxypeptidase A domain-containing protein; Fusarium euwallaceae; 4.187e-52 |
| XANPAGTX0501_002406-T2 | not in cluster | NA | Non-DGE | 0.89 | 89.56079 | 819 | IPR011050 Pectin lyase fold/virulence factor;IPR012334 Pectin lyase fold;IPR024535 Pectate lyase superfamily protein | GH55 | NA | Non-antimicrobial | 3EQN; Crystal structure of beta-1,3-glucanase from Phanerochaete chrysosporium (Lam55A); 2.544e-51 | 5M5Z; Chaetomium thermophilum beta-1-3-glucanase; 1.217e-50 | A0A135LHY7; Pectin lyase fold/virulence factor; Penicillium patulum (Penicillium griseofulvum); 2.282e-81 | A0A1V6PF20; Pectate lyase superfamily protein domain-containing protein; Penicillium decumbens; 5.583e-81 |
| XANPAGTX0501_002409-T1 | not in cluster | NA | Upregulated in lichen | 0.5 | 67.14336 | 110 | IPR001338 Hydrophobin | NA | NA | Non-antimicrobial | NA | NA | Q96VD0; Hydrophobin H1; Xanthoria parietina; 7.874e-10 | B9DR15; Hydrophobin; Xanthoria sp. 1653(143.2); 1.102e-08 |
| XANPAGTX0501_002636-T1 | not in cluster | NA | Non-DGE | 0.88 | 86.39282 | 639 | IPR002642 Lysophospholipase, catalytic domain;IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase | NA | NA | Non-antimicrobial | 5IZ5; Human GIVD cytosolic phospholipase A2; 2.78e-16 | 5IZ5; Human GIVD cytosolic phospholipase A2; 2.31e-15 | A0A229XYZ1; deleted; ; 1.222e-73 | G3Y902; Lysophospholipase (EC 3.1.1.5); Aspergillus niger (strain ATCC 1015 / CBS 113.46 / FGSC A1144 / LSHB Ac4 / NCTC 3858a / NRRL 328 / USDA 3528.7); 4.446e-72 |
| XANPAGTX0501_003126-T1 | not in cluster | NA | Non-DGE | 0.89 | 89.33528 | 428 | IPR021047 Mannosyltransferase 1, CMT1 | GT69 | NA | Antimicrobial | NA | NA | C1GWU2; Polysaccharide export protein (CAP59); Paracoccidioides lutzii (strain ATCC MYA-826 / Pb01) (Paracoccidioides brasiliensis); 6.287e-51 | A0A6A6S4M6; Glycosyltransferase family 69 protein; Massarina eburnea CBS 473.64; 8.481e-49 |
| XANPAGTX0501_003130-T1 | not in cluster | NA | Non-DGE | 0.71 | 88.51188 | 489 | IPR000209 Peptidase S8/S53 domain;IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9;IPR015500 Peptidase S8, subtilisin-related;IPR022398 Peptidase S8, subtilisin, His-active site;IPR023828 Peptidase S8, subtilisin, Ser-active site;IPR034193 Proteinase K-like catalytic domain;IPR036852 Peptidase S8/S53 domain superfamily;IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily | NA | S08A | Non-antimicrobial | 7A9F; Co-substituted Keggin silicotungstate with covalent bond to proteinase K; 3.576e-35 | 3F7M; Crystal structure of apo Cuticle-Degrading Protease (ver112) from Verticillium psalliotae; 4.509e-35 | W9YTV7; Cerevisin; Capronia epimyces CBS 606.96; 2.537e-74 | A0A0D2BNZ3; Subtilisin-like protease; Exophiala spinifera; 2.688e-74 |
| XANPAGTX0501_003186-T1 | not in cluster | NA | Upregulated in lichen | 0.79 | 86.69064 | 188 | NA | NA | NA | Non-antimicrobial | NA | NA | A0A3D8RZY1; Uncharacterized protein; Coleophoma cylindrospora; 2.059e-11 | A0A094GHG2; AB hydrolase-1 domain-containing protein; Pseudogymnoascus sp. VKM F-4518 (FW-2643); 9.153e-10 |
| XANPAGTX0501_003307-T1 | not in cluster | NA | Non-DGE | 0.68 | 80.35710 | 145 | IPR036514 SGNH hydrolase superfamily | NA | NA | Non-antimicrobial | NA | NA | A0A6A6IIT9; SGNH hydrolase; Trematosphaeria pertusa; 1.693e-08 | A0A478EAD9; SGNH hydrolase-type esterase domain-containing protein; Talaromyces pinophilus (Penicillium pinophilum); 4.656e-08 |
| XANPAGTX0501_003434-T1 | not in cluster | NA | Non-DGE | 0.9 | 94.06456 | 283 | IPR003154 S1/P1 nuclease;IPR008947 Phospholipase C/P1 nuclease domain superfamily | NA | NA | Non-antimicrobial | 5FBF; S1 nuclease from Aspergillus oryzae in complex with two molecules of 2’-deoxycytidine-5’-monophosphate; 7.177e-22 | 1AK0; P1 NUCLEASE IN COMPLEX WITH A SUBSTRATE ANALOG; 2.691e-21 | A0A0C3Q6Y7; Uncharacterized protein; Tulasnella calospora MUT 4182; 1.914e-23 | A0A2D3V2J1; Related to nuclease S1; Ramularia collo-cygni; 3.019e-23 |
| XANPAGTX0501_003448-T1 | not in cluster | NA | Upregulated in lichen | 0.73 | 78.49583 | 187 | NA | NA | NA | Non-antimicrobial | NA | NA | NA | NA |
| XANPAGTX0501_003490-T1 | not in cluster | NA | Non-DGE | 0.72 | 85.74232 | 538 | IPR001623 DnaJ domain;IPR011990 Tetratricopeptide-like helical domain superfamily;IPR013026 None;IPR019734 Tetratricopeptide repeat;IPR036869 Chaperone J-domain superfamily | NA | NA | Antimicrobial | NA | NA | A0A3M7I0K9; J domain-containing protein; Hortaea werneckii; 9.659e-38 | A0A3M6XUH3; J domain-containing protein; Hortaea werneckii; 1.363e-37 |
| XANPAGTX0501_003643-T1 | not in cluster | NA | Non-DGE | 0.51 | 64.64147 | 469 | NA | NA | NA | Below pLDDT threshold | NA | NA | A0A1E1LJD6; Related to AGA1 A-agglutinin anchor subunit; Rhynchosporium agropyri; 9.086e-33 | A0A0C3D8D2; Ribosomal protein s17; Oidiodendron maius (strain Zn); 4.987e-32 |
| XANPAGTX0501_003851-T1 | not in cluster | NA | Non-DGE | 0.54 | 81.14339 | 304 | NA | NA | NA | Non-antimicrobial | 1R0S; Crystal structure of ADP-ribosyl cyclase Glu179Ala mutant; 0.0001116 | 4XJT; Human CD38 complexed with inhibitor 2 [4-[(2,6-dimethylbenzyl)amino]-2-methylquinoline-8-carboxamide]; 0.000683 | T0F6N0; Intein C-terminal splicing domain protein; Leptospira broomii serovar Hurstbridge str. 5399; 1.235e-07 | A0A2D3W406; DUF637 domain-containing protein; Sulfurospirillum sp. UBA11407; 1.884e-07 |
| XANPAGTX0501_003873-T1 | not in cluster | NA | Upregulated in lichen | 0.8 | 85.71939 | 245 | IPR002053 Glycoside hydrolase, family 25;IPR017853 Glycoside hydrolase superfamily;IPR018077 Glycoside hydrolase, family 25 subgroup | GH25 | NA | Non-antimicrobial | 6ZMV; Structure of muramidase from Trichobolus zukalii; 5.817e-32 | 2X8R; The structure of a family GH25 lysozyme from Aspergillus fumigatus; 2.217e-28 | A0A6I5H8T3; Hydrolase; Streptomyces sp. SID486; 3.001e-24 | A0A6B1PIJ5; deleted; ; 5.997e-24 |
| XANPAGTX0501_004034-T1 | not in cluster | NA | Non-DGE | 0.57 | 80.69364 | 143 | NA | NA | NA | Non-antimicrobial | 8B2G; SH3-like domain from Penicillium virgatum muramidase; 0.0001431 | NA | B6QI84; MBL2-like secreted peptide, putative; Talaromyces marneffei (strain ATCC 18224 / CBS 334.59 / QM 7333) (Penicillium marneffei); 1.238e-10 | A0A094A8R6; Uncharacterized protein; Pseudogymnoascus sp. VKM F-3808; 2.517e-10 |
| XANPAGTX0501_004329-T1 | not in cluster | NA | Upregulated in lichen | 0.73 | 82.24983 | 176 | IPR020915 Uncharacterised protein family UPF0311 | NA | NA | Non-antimicrobial | 3G7G; Crystal structure of the protein with unknown function from Clostridium acetobutylicum ATCC 824; 1.897e-08 | 3G7G; Crystal structure of the protein with unknown function from Clostridium acetobutylicum ATCC 824; 3.326e-08 | A0A6A5YFR6; Secreted protein NIS1; Lophiotrema nucula; 6.873e-14 | A0A0D2EUD7; Dirigent protein; Exophiala xenobiotica; 8.375e-13 |
| XANPAGTX0501_004437-T1 | not in cluster | NA | Non-DGE | 0.89 | 90.68023 | 304 | NA | NA | NA | Non-antimicrobial | NA | NA | A0A364KRR8; Uncharacterized protein; Talaromyces amestolkiae; 5.796e-35 | A0A6A6RRD5; Uncharacterized protein; Massarina eburnea CBS 473.64; 3.692e-33 |
| XANPAGTX0501_004920-T1 | not in cluster | NA | Non-DGE | 0.8 | 78.62424 | 516 | IPR019236 Phosphatidate phosphatase APP1, catalytic domain | NA | NA | Non-antimicrobial | NA | NA | A0A178CYH7; Phosphatidate phosphatase APP1 catalytic domain-containing protein; Fonsecaea nubica; 2.457e-67 | A0A517LQY5; Phosphatidate phosphatase APP1 catalytic domain-containing protein; Venturia effusa; 2.939e-67 |
| XANPAGTX0501_005061-T1 | not in cluster | NA | Upregulated in lichen | 0.77 | 82.27010 | 197 | NA | NA | NA | Non-antimicrobial | NA | NA | A0A5N6L4G7; Late sexual development protein; Carpinus fangiana; 9.341e-11 | J3SFR0; Later sexual development protein; Cordyceps militaris (Caterpillar fungus) (Clavaria militaris); 5.096e-10 |
| XANPAGTX0501_005118-T1 | not in cluster | NA | Upregulated in culture | 0.81 | 90.23024 | 206 | NA | NA | NA | Antimicrobial | 4BK7; Crystal Structure of a variant of the Major Birch Pollen Allergen Bet v 1; 2.475e-05 | 2NS9; Crystal structure of protein APE2225 from Aeropyrum pernix K1, Pfam COXG; 0.000252 | A0A2T3A6X0; Uncharacterized protein; Coniella lustricola; 6.598e-21 | A0A4Z0Y6Z7; Uncharacterized protein; Xylaria hypoxylon; 6.014e-20 |
| XANPAGTX0501_005540-T1 | not in cluster | NA | Non-DGE | 0.81 | 81.65689 | 601 | IPR021102 Peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase A | NA | NA | Non-antimicrobial | NA | NA | A0A1W5D9F6; Peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase A; Lasallia pustulata; 1.304e-68 | W9CIP8; Putative Peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase A; Sclerotinia borealis (strain F-4128); 6.013e-65 |
| XANPAGTX0501_005629-T1 | not in cluster | NA | Upregulated in lichen | 0.87 | 91.80710 | 420 | IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily;IPR030395 Glycerophosphodiester phosphodiesterase domain | NA | NA | Antimicrobial | 1YDY; Crystal structure of periplasmic glycerophosphodiester phosphodiesterase from Escherichia coli; 6.608e-17 | 3L12; Crystal structure of Putative glycerophosphoryl diester phosphodiesterase (YP_165505.1) from Silicibacter pomeroyi DSS-3 at 1.60 A resolution; 3.272e-13 | A0A0B8P194; glycerophosphodiester phosphodiesterase (EC 3.1.4.46); Vibrio ishigakensis; 5.68e-55 | A0A6T9Y4D2; glycerophosphodiester phosphodiesterase (EC 3.1.4.46); Alteromonas macleodii (Pseudoalteromonas macleodii); 9.083e-55 |
| XANPAGTX0501_005656-T1 | not in cluster | NA | Non-DGE | 0.78 | 85.19818 | 231 | IPR025331 Tuberculosis necrotizing toxin | NA | NA | Non-antimicrobial | 8PMR; NADase from Aspergillus fumigatus with mutated calcium binding motif (D219A/E220A); 1.141e-25 | 6YGF; NADase from Aspergillus fumigatus with trapped reaction products; 7.19e-25 | A0A1J7J3X2; TNT domain-containing protein; Coniochaeta ligniaria NRRL 30616; 2.685e-28 | S3C0L4; TNT domain-containing protein; Ophiostoma piceae (strain UAMH 11346) (Sap stain fungus); 3.73e-28 |
| XANPAGTX0501_005892-T1 | not in cluster | NA | Non-DGE | 0.75 | 87.75533 | 182 | IPR017850 Alkaline-phosphatase-like, core domain superfamily | NA | NA | Non-antimicrobial | NA | NA | A0A1V1TF11; Uncharacterized protein; Xylariales sp. No.14919; 1.838e-22 | A0A439CRK1; alkaline phosphatase (EC 3.1.3.1); Xylaria grammica; 1.939e-20 |
| XANPAGTX0501_006290-T1 | not in cluster | NA | Non-DGE | 0.81 | 90.83000 | 155 | NA | NA | NA | Non-antimicrobial | NA | NA | W9YLS9; Uncharacterized protein; Capronia coronata CBS 617.96; 4.986e-21 | A0A194VTQ5; Uncharacterized protein; Valsa mali; 1.01e-19 |
| XANPAGTX0501_006382-T1 | not in cluster | NA | Upregulated in lichen | 0.89 | 90.74412 | 413 | NA | NA | NA | Antimicrobial | 6FWG; Structure of an E333Q variant of the GH99 endo-alpha-mannanase from Bacteroides xylanisolvens in complex with tetramannoside yeast mannan fragment; 8.222e-17 | 6FWM; Structure of the GH99 endo-alpha-mannanase from Bacteroides xylanisolvens in complex with alpha-Glc-1,3-1,2-anhydro-mannose hydrolyzed by enzyme; 9.306e-17 | A0A6A6SUE6; Uncharacterized protein; Lophiostoma macrostomum CBS 122681; 2.142e-59 | A0A2P6MTX4; Xylosidase/arabinosidase; Planoprotostelium fungivorum; 1.281e-41 |
| XANPAGTX0501_006534-T1 | not in cluster | NA | Non-DGE | 0.75 | 78.95544 | 417 | IPR000782 FAS1 domain;IPR036378 FAS1 domain superfamily | NA | NA | Non-antimicrobial | 5NV6; Structure of human transforming growth factor beta-induced protein (TGFBIp).; 1.457e-17 | 7AS7; Crystal structure of the GCD-associated TGFBIp mutant R124H; 4.57e-17 | A0A1W5D899; FAS1 domain; Lasallia pustulata; 1.098e-46 | A0A165FZY9; FAS1 domain-containing protein; Xylona heveae (strain CBS 132557 / TC161); 1.199e-44 |
| XANPAGTX0501_006631-T1 | not in cluster | NA | Non-DGE | 0.54 | 74.07682 | 258 | IPR008659 Yeast cell wall synthesis Kre9/Knh1, C-terminal;IPR018466 Yeast cell wall synthesis Kre9/Knh1-like, N-terminal | NA | NA | Non-antimicrobial | NA | NA | A0A2I0S4R5; deleted; ; 4.603e-24 | A0A0F4GR13; Uncharacterized protein; Zymoseptoria brevis; 2.21e-23 |
| XANPAGTX0501_006635-T1 | not in cluster | NA | Non-DGE | 0.65 | 70.70920 | 213 | NA | NA | NA | Non-antimicrobial | NA | NA | A0A5M8PRM9; Uncharacterized protein; Lasallia pustulata; 2.628e-15 | A0A1W5D8P3; Uncharacterized protein; Lasallia pustulata; 8.396e-13 |
| XANPAGTX0501_006937-T1 | not in cluster | NA | Non-DGE | 0.64 | 60.82756 | 356 | NA | NA | NA | Below pLDDT threshold | NA | NA | A0A4S8QVN8; Uncharacterized protein; Botrytis galanthina; 2.439e-10 | W9CAJ0; Uncharacterized protein; Sclerotinia borealis (strain F-4128); 3.978e-09 |
| XANPAGTX0501_006958-T1 | not in cluster | NA | Non-DGE | 0.82 | 85.80254 | 535 | IPR003137 PA domain;IPR007484 Peptidase M28;IPR041756 Peptidase M28, SGAP-like | NA | M28A | Antimicrobial | 8AC9; Structure of Pseudomonas aeruginosa aminopeptidase, PaAP_T; 5.269e-51 | 8ACG; Structure of Pseudomonas aeruginosa aminopeptidase, PaAP_T E340A mutant; 1.883e-49 | A0A6A6S275; Peptide hydrolase (EC 3.4.-.-); Massarina eburnea CBS 473.64; 4.081e-70 | A0A6A6PEK6; Peptide hydrolase (EC 3.4.-.-); Lineolata rhizophorae; 2.051e-66 |
| XANPAGTX0501_007039-T1 | not in cluster | NA | Non-DGE | 0.51 | 70.60086 | 278 | NA | NA | NA | Non-antimicrobial | 6X4T; Crystal structure of ICOS-L in complex with Prezalumab and VNAR domain; 0.0001918 | NA | A0A3M0WE15; Uncharacterized protein; Chaetothyriales sp. CBS 134920; 6.04e-23 | A0A3M7MWN4; Uncharacterized protein; Chaetothyriales sp. CBS 132003; 6.399e-23 |
| XANPAGTX0501_007093-T2 | not in cluster | NA | Non-DGE | 0.84 | 85.95366 | 369 | IPR013126 Heat shock protein 70 family | NA | NA | Non-antimicrobial | 5OBV; Mycoplasma genitalium DnaK deletion mutant lacking SBDalpha in complex with ADP and Pi.; 1.644e-12 | 6CZ1; Crystal structure of ATPase domain of Human GRP78 bound to Ver155008; 1.644e-12 | C5FXE3; Uncharacterized protein; Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) (Microsporum canis); 2.668e-33 | A0A395HEJ5; Aminoglycoside phosphotransferase domain-containing protein; Aspergillus ibericus CBS 121593; 3.088e-27 |
| XANPAGTX0501_007316-T1 | not in cluster | NA | Non-DGE | 0.91 | 94.15843 | 388 | IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase;IPR011013 Galactose mutarotase-like domain superfamily;IPR014718 Glycoside hydrolase-type carbohydrate-binding | NA | NA | Non-antimicrobial | 1LUR; Crystal Structure of the GalM/aldose Epimerase Homologue from C. elegans, Northeast Structural Genomics Target WR66; 5.745e-31 | 1SO0; Crystal structure of human galactose mutarotase complexed with galactose; 1.329e-30 | A0A1W5D5J2; Aldose 1-epimerase; Lasallia pustulata; 7.406e-65 | A0A150V8R4; Aldose 1-epimerase; Acidomyces richmondensis BFW; 1.806e-58 |
| XANPAGTX0501_007388-T1 | not in cluster | NA | Upregulated in culture | 0.89 | 88.42941 | 563 | IPR002372 Pyrrolo-quinoline quinone repeat;IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily;IPR015943 WD40/YVTN repeat-like-containing domain superfamily;IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat | NA | NA | Antimicrobial | 7CDL; holo-methanol dehydrogenase (MDH) with Cys131-Cys132 reduced from Methylococcus capsulatus (Bath); 3.738e-20 | 2D0V; Crystal structure of methanol dehydrogenase from Hyphomicrobium denitrificans; 2.31e-19 | T0KY48; PQQ enzyme repeat protein; Colletotrichum gloeosporioides (strain Cg-14) (Anthracnose fungus) (Glomerella cingulata); 5.883e-64 | A0A1Y1ZWW9; Quinon protein alcohol dehydrogenase-like superfamily; Clohesyomyces aquaticus; 2.844e-48 |
| XANPAGTX0501_007437-T1 | not in cluster | NA | Non-DGE | 0.55 | 63.38476 | 292 | NA | NA | NA | Below pLDDT threshold | NA | NA | A0A7C8IH86; Uncharacterized protein; Massariosphaeria phaeospora; 1.818e-13 | E3RDR6; Uncharacterized protein; Pyrenophora teres f. teres (strain 0-1) (Barley net blotch fungus) (Drechslera teres f. teres); 8.054e-13 |
| XANPAGTX0501_007655-T1 | not in cluster | NA | Upregulated in lichen | 0.71 | 73.85991 | 466 | IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily | NA | NA | Non-antimicrobial | 2ISD; PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C-DELTA1 FROM RAT; 0.00091 | NA | A0A3E2H320; PLC-like phosphodiesterase; Scytalidium lignicola (Hyphomycete); 1.563e-51 | A0A420HWP5; Putative secreted protein; Golovinomyces cichoracearum; 2.911e-51 |
| XANPAGTX0501_007769-T1 | not in cluster | NA | Non-DGE | 0.75 | 79.42492 | 626 | IPR020067 Frizzled domain;IPR024338 Stretch-activated cation channel Mid1/Calcium influx-promoting protein Ehs1 | NA | NA | Antimicrobial | NA | NA | A0A5M8PTI9; Calcium channel MID1; Lasallia pustulata; 1.168e-57 | A0A2S4PQ51; FZ domain-containing protein; Erysiphe pulchra; 2.473e-53 |
| XANPAGTX0501_008252-T1 | not in cluster | NA | Non-DGE | 0.82 | 86.45067 | 404 | IPR032675 Leucine-rich repeat domain superfamily | NA | NA | Non-antimicrobial | NA | NA | C5FEL3; Ecm33; Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) (Microsporum canis); 5.036e-25 | F0U581; GPI-anchored cell wall organization protein; Ajellomyces capsulatus (strain H88) (Darling’s disease fungus) (Histoplasma capsulatum); 1.644e-22 |
| XANPAGTX0501_008270-T1 | not in cluster | NA | Upregulated in lichen | 0.74 | 77.95650 | 200 | NA | NA | NA | Non-antimicrobial | NA | NA | A0A318ZGC2; Uncharacterized protein; Aspergillus saccharolyticus JOP 1030-1; 1.402e-09 | A0A2K9YDH4; Uncharacterized protein; Cladonia uncialis subsp. uncialis; 1.744e-09 |
| XANPAGTX0501_008637-T1 | not in cluster | NA | Non-DGE | 0.61 | 68.18693 | 476 | NA | NA | NA | Non-antimicrobial | NA | NA | C4JJA1; Uncharacterized protein; Uncinocarpus reesii (strain UAMH 1704); 2.814e-36 | S8B6S8; Uncharacterized protein; Penicillium oxalicum (strain 114-2 / CGMCC 5302) (Penicillium decumbens); 4.968e-36 |
| XANPAGTX0501_008763-T1 | not in cluster | NA | Non-DGE | 0.86 | 88.38733 | 389 | IPR036278 Sialidase superfamily | GH93 | NA | Non-antimicrobial | 2W5N; Native structure of the GH93 alpha-L-arabinofuranosidase of Fusarium graminearum; 2.388e-14 | 3A71; High resolution structure of Penicillium chrysogenum alpha-L-arabinanase; 2.909e-14 | A0A139I7Q9; Sialidase domain-containing protein; Pseudocercospora musae; 3.798e-37 | Q2HC91; Sialidase domain-containing protein; Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970) (Soil fungus); 8.043e-29 |
| XANPAGTX0501_008858-T1 | not in cluster | NA | Non-DGE | 0.9 | 92.51140 | 572 | IPR000101 Gamma-glutamyltranspeptidase;IPR029055 Nucleophile aminohydrolases, N-terminal;IPR043137 Gamma-glutamyltranspeptidase, small subunit;IPR043138 Gamma-glutamyltranspeptidase, large subunit, C-terminal domain | NA | T03 | Non-antimicrobial | 2E0W; T391A precursor mutant protein of gamma-Glutamyltranspeptidase from Escherichia coli; 1.118e-43 | 4Y23; Crystal structure of T399A precursor mutant protein of gamma-glutamyl transpeptidase from Bacillus licheniformis; 2.683e-41 | A0A0F4YDN3; Glutathione hydrolase (EC 2.3.2.2) (EC 3.4.19.13) (Gamma-glutamyltransferase) (Gamma-glutamyltranspeptidase); Rasamsonia emersonii CBS 393.64; 6.968e-83 | A0A2I2GMW9; Zn(2)-C6 fungal-type domain-containing protein; Aspergillus steynii IBT 23096; 4.193e-81 |
| XANPAGTX0501_009170-T1 | not in cluster | NA | Upregulated in culture | 0.72 | 81.22039 | 282 | IPR000334 Glycoside hydrolase, family 45;IPR036908 RlpA-like domain superfamily | GH45 | NA | Antimicrobial | 4ENG; STRUCTURE OF ENDOGLUCANASE V CELLOHEXAOSE COMPLEX; 3.143e-29 | 6MVI; Apo Cel45A from Neurospora crassa OR74A; 1.277e-28 | A0A2B7YD39; Cellulase (EC 3.2.1.4); Helicocarpus griseus UAMH5409; 1.565e-31 | A0A074VM44; Cellulase (EC 3.2.1.4); Aureobasidium melanogenum CBS 110374; 1.565e-31 |
| XANPAGTX0501_009211-T1 | not in cluster | NA | Non-DGE | 0.91 | 92.80117 | 707 | IPR003137 PA domain;IPR007365 Transferrin receptor-like, dimerisation domain;IPR007484 Peptidase M28;IPR036757 Transferrin receptor-like, dimerisation domain superfamily | NA | M28B | Non-antimicrobial | 4P44; X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a phosphoramidate inhibitor JRB-4-81; 1.814e-68 | 4P4D; X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a phosphoramidate inhibitor MP1C; 2.417e-68 | A0A7C8MSS2; Heterokaryon incompatibility domain-containing protein; Xylaria multiplex; 0 | A0A135UQD7; PA domain-containing protein; Colletotrichum nymphaeae SA-01; 0 |
| XANPAGTX0501_009293-T1 | not in cluster | NA | Non-DGE | 0.69 | 84.51065 | 107 | NA | NA | NA | Antimicrobial | NA | NA | A0A1L9RFQ7; Uncharacterized protein; Aspergillus wentii DTO 134E9; 2.072e-08 | A0A017S360; Uncharacterized protein; Aspergillus ruber (strain CBS 135680); 4.85e-08 |
| XANPAGTX0501_009521-T1 | not in cluster | NA | Non-DGE | 0.92 | 93.58860 | 979 | IPR000322 Glycoside hydrolase family 31;IPR011013 Galactose mutarotase-like domain superfamily;IPR013780 Glycosyl hydrolase, all-beta;IPR017853 Glycoside hydrolase superfamily;IPR025887 Glycoside hydrolase family 31, N-terminal domain;IPR030458 Glycosyl hydrolases family 31, active site;IPR033403 Domain of unknown function DUF5110 | GH31 | NA | Non-antimicrobial | 5DL0; Crystal structure of glucosidase II alpha subunit (Glc1Man2-bound from); 0 | 5DKX; Crystal structure of glucosidase II alpha subunit (Tris-bound from); 0 | A0A4P6XXT6; Glucosidase II subunit alpha; Metschnikowia aff. pulcherrima; 0 | A2DBB0; Glucosidase II subunit alpha; Trichomonas vaginalis (strain ATCC PRA-98 / G3); 6.364e-101 |
| XANPAGTX0501_009694-T1 | not in cluster | NA | Non-DGE | 0.73 | 74.51758 | 702 | IPR017853 Glycoside hydrolase superfamily;IPR039514 Endo-beta-1,6-galactanase-like | GH30 | NA | Antimicrobial | 7N6O; The crystal structure of the GH30 subfamily 10 enzyme, AcXbh30A from Acetivibrio clariflavus in complex with xylobiose; 3.122e-31 | 5CXP; X-ray crystallographic protein structure of the glycoside hydrolase family 30 subfamily 8 xylanase, Xyn30A, from Clostridium acetobutylicum; 1.856e-24 | A0A6J3MFN7; Glycoside hydrolase family 30 protein; Dissoconium aciculare CBS 342.82; 1.804e-62 | B0DQ00; Glycoside hydrolase family 5 protein; Laccaria bicolor (strain S238N-H82 / ATCC MYA-4686) (Bicoloured deceiver) (Laccaria laccata var. bicolor); 1.794e-61 |
| XANPAGTX0501_009729-T1 | not in cluster | NA | Non-DGE | 0.77 | 82.65681 | 191 | NA | GH134 | NA | Non-antimicrobial | 5JTS; Structure of a beta-1,4-mannanase, SsGH134.; 3.307e-09 | 5XUL; Complex structure (RmMan134A-M6).; 1.15e-08 | A0A1L9SZB2; Uncharacterized protein; Aspergillus sydowii CBS 593.65; 1.913e-09 | A0A1B8GLK5; Uncharacterized protein; Pseudogymnoascus verrucosus; 5.906e-09 |
| XANPAGTX0501_009761-T1 | not in cluster | NA | Upregulated in culture | 0.73 | 84.12986 | 211 | IPR001283 Cysteine-rich secretory protein-related;IPR014044 CAP domain;IPR018244 Allergen V5/Tpx-1-related, conserved site;IPR034120 None;IPR035940 CAP superfamily | NA | NA | Non-antimicrobial | 5JYS; Pry1 CAP domain; 2.82e-16 | 1SMB; Crystal Structure of Golgi-Associated PR-1 protein; 4.65e-13 | A0A1B8GSL1; SCP domain-containing protein; Pseudogymnoascus verrucosus; 2.459e-23 | A0A436ZUH8; SCP domain-containing protein; Arthrobotrys flagrans; 8.976e-21 |
| XANPAGTX0501_009880-T1 | not in cluster | NA | Non-DGE | 0.69 | 75.76424 | 229 | NA | NA | NA | Antimicrobial | NA | NA | U4L2B3; Uncharacterized protein; Pyronema omphalodes (strain CBS 100304) (Pyronema confluens); 1.082e-19 | A0A1Y2LYF1; SRCR domain-containing protein; Epicoccum nigrum (Soil fungus) (Epicoccum purpurascens); 3.713e-17 |
| XANPAGTX0501_009902-T1 | not in cluster | NA | Upregulated in culture | 0.81 | 82.82577 | 291 | IPR001148 Alpha carbonic anhydrase domain;IPR036398 Alpha carbonic anhydrase domain superfamily;IPR041891 Carbonic anhydrase, prokaryotic-like | NA | NA | Non-antimicrobial | 3F7U; Crystal Structure of soluble domain of CA4 in complex with small molecule.; 1.063e-15 | 7POM; Three dimensional structure of human carbonic anhydrase IX in complex with sulfonamide; 1.13e-15 | R7YXY8; Alpha-carbonic anhydrase domain-containing protein; Coniosporium apollinis (strain CBS 100218) (Rock-inhabiting black yeast); 3.485e-38 | A0A3M2SB97; Alpha-carbonic anhydrase domain-containing protein; Fusarium kuroshium; 1.106e-37 |
| XANPAGTX0501_009945-T1 | not in cluster | NA | Non-DGE | 0.64 | 64.67120 | 259 | NA | NA | NA | Below pLDDT threshold | NA | NA | Q2GRQ4; Uncharacterized protein; Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970) (Soil fungus); 7.202e-05 | NA |
| XANPAGTX0501_009972-T1 | not in cluster | NA | Upregulated in lichen | 0.85 | 89.22651 | 656 | IPR000209 Peptidase S8/S53 domain;IPR015366 Peptidase S53, activation domain;IPR030400 Sedolisin domain;IPR036852 Peptidase S8/S53 domain superfamily | NA | S53 | Antimicrobial | 3EE6; Crystal Structure Analysis of Tripeptidyl peptidase -I; 1.051e-44 | 3EDY; Crystal Structure of the Precursor Form of Human Tripeptidyl-Peptidase 1; 1.486e-44 | A0A5C3NB46; Subtilisin-like protein; Heliocybe sulcata; 2.6e-89 | S8EJ40; Peptidase S53 domain-containing protein; Fomitopsis schrenkii (Brown rot fungus); 1.85e-72 |
| XANPAGTX0501_010027-T1 | not in cluster | NA | Upregulated in lichen | 0.54 | 56.30980 | 250 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_010044-T1 | not in cluster | NA | Upregulated in lichen | 0.67 | 84.62511 | 229 | IPR002937 Amine oxidase;IPR036188 FAD/NAD(P)-binding domain superfamily | NA | NA | Non-antimicrobial | 3KU9; X-ray structure of the mutant lys300met of polyamine oxidase from zea mays in complex with spermine; 2.898e-08 | 1YY5; Crystal structure of Fms1, a polyamine oxidase from Yeast; 9.663e-05 | A0A1Y1ZCU9; Amine oxidase domain-containing protein; Clohesyomyces aquaticus; 2.895e-23 | A0A6A6IC26; Amine oxidase (EC 1.4.3.-); Trematosphaeria pertusa; 1.23e-20 |
| XANPAGTX0501_010179-T1 | not in cluster | NA | Non-DGE | 0.7 | 88.40682 | 773 | IPR002509 NodB homology domain;IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel | CE4 | NA | Antimicrobial | 7BLY; Structure of the chitin deacetylase AngCDA from Aspergillus niger; 5.956e-15 | 2Y8U; A. nidulans chitin deacetylase; 5.66e-14 | A0A395IMC3; NodB homology domain-containing protein; Monilinia fructigena; 1.698e-64 | A0A7H8RGX4; RNA helicase (EC 3.6.4.13); Talaromyces rugulosus; 8.317e-51 |
| XANPAGTX0501_010191-T1 | not in cluster | NA | Upregulated in culture | 0.81 | 88.59765 | 221 | IPR000675 Cutinase/acetylxylan esterase;IPR011150 Cutinase, monofunctional;IPR029058 Alpha/Beta hydrolase fold | CE5 | NA | Antimicrobial | 4PSD; Structure of Trichoderma reesei cutinase native form.; 1.768e-17 | 3DEA; Glomerella cingulata PETFP-cutinase complex; 8.199e-13 | A0A6A6U7K6; Cutinase (EC 3.1.1.74); Microthyrium microscopicum; 4.921e-20 | A0A3M7EGU2; Cutinase (EC 3.1.1.74); Hortaea werneckii; 7.466e-18 |
| XANPAGTX0501_010250-T1 | not in cluster | NA | Upregulated in lichen | 0.78 | 81.44745 | 141 | NA | NA | NA | Non-antimicrobial | NA | NA | A0A395I706; Ig-like domain-containing protein; Aspergillus homomorphus (strain CBS 101889); 5.921e-15 | A0A6A5RM64; Ig-like domain-containing protein; Didymella exigua CBS 183.55; 1.416e-14 |
| XANPAGTX0501_010326-T1 | not in cluster | NA | Non-DGE | 0.64 | 82.37849 | 146 | IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal;IPR036188 FAD/NAD(P)-binding domain superfamily | NA | NA | Non-antimicrobial | 8BXL; Patulin Synthase from Penicillium expansum; 3.518e-11 | 4H7U; Crystal structure of pyranose dehydrogenase from Agaricus meleagris, wildtype; 1.628e-08 | C9SEJ0; Choline dehydrogenase; Verticillium alfalfae (strain VaMs.102 / ATCC MYA-4576 / FGSC 10136) (Verticillium wilt of alfalfa) (Verticillium albo-atrum); 3.414e-14 | A0A0C4EB00; Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein; Magnaporthiopsis poae (strain ATCC 64411 / 73-15) (Kentucky bluegrass fungus) (Magnaporthe poae); 7.537e-14 |
| XANPAGTX0501_010370-T1 | not in cluster | NA | Upregulated in lichen | 0.53 | 63.13854 | 308 | IPR003609 PAN/Apple domain | NA | NA | Below pLDDT threshold | NA | NA | A0A2T2NYB4; Apple domain-containing protein; Corynespora cassiicola Philippines; 2.64e-21 | A0A6A6Y414; Apple domain-containing protein; Mytilinidion resinicola; 2.453e-20 |
| XANPAGTX0501_010426-T1 | not in cluster | NA | Non-DGE | 0.87 | 89.27199 | 337 | IPR018170 Aldo/keto reductase, conserved site;IPR020471 Aldo-keto reductase;IPR023210 NADP-dependent oxidoreductase domain;IPR036812 NADP-dependent oxidoreductase domain superfamily | NA | NA | Non-antimicrobial | 5HNT; Crystal Structure of AKR1C3 complexed with CAPE; 2.98e-30 | 4FAL; Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 in complex with 3-((3,4-dihydroisoquinolin-2(1H)-yl)sulfonyl)-N-methylbenzamide (80); 1.409e-28 | A0A2V1E8K6; Aldo/keto reductase; Periconia macrospinosa; 1.788e-43 | A0A6A5TPB9; Aldo/keto reductase; Byssothecium circinans; 3.235e-43 |
| XANPAGTX0501_010590-T1 | not in cluster | NA | Non-DGE | 0.63 | 86.96828 | 406 | IPR001568 Ribonuclease T2-like;IPR018188 Ribonuclease T2, His active site 1;IPR033130 Ribonuclease T2, His active site 2;IPR033697 Ribonuclease T2, eukaryotic;IPR036430 Ribonuclease T2-like superfamily | NA | NA | Antimicrobial | 3TBJ; The 1.7A crystal structure of Actibind a T2 ribonucleases as antitumorigenic agents; 8.715e-30 | 1BOL; THE CRYSTAL STRUCTURE OF RIBONUCLEASE RH FROM RHIZOPUS NIVEUS AT 2.0 A RESOLUTION; 1.534e-22 | A0A1E1KC66; Related to ribonucleases; Rhynchosporium agropyri; 6.326e-52 | A0A179TXI2; deleted; ; 2.654e-48 |
| XANPAGTX0501_010682-T1 | not in cluster | NA | Upregulated in lichen | 0.5 | 56.12104 | 251 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_000013-T1 | pTM below threshold | NA | Non-DGE | 0.38 | 61.66691 | 256 | NA | NA | NA | Below pLDDT threshold | NA | NA | C1GWS1; Extracellular membrane protein CFEM domain-containing protein; Paracoccidioides lutzii (strain ATCC MYA-826 / Pb01) (Paracoccidioides brasiliensis); 1.568e-08 | A0A1J9QV12; Extracellular membrane protein CFEM domain-containing protein; Blastomyces percursus; 2.619e-08 |
| XANPAGTX0501_000052-T1 | pTM below threshold | NA | Non-DGE | 0.38 | 42.72020 | 205 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_000098-T1 | pTM below threshold | NA | Non-DGE | 0.28 | 35.07247 | 170 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_000162-T1 | pTM below threshold | NA | Upregulated in lichen | 0.14 | 48.05267 | 105 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_000212-T1 | pTM below threshold | NA | Non-DGE | 0.22 | 34.04358 | 265 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_000271-T1 | pTM below threshold | NA | Non-DGE | 0.22 | 35.77524 | 368 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_000324-T1 | pTM below threshold | NA | Non-DGE | 0.43 | 47.81232 | 298 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_000327-T1 | pTM below threshold | NA | Non-DGE | 0.32 | 34.56706 | 194 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_000401-T1 | pTM below threshold | NA | Upregulated in culture | 0.32 | 40.85944 | 216 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_000434-T1 | pTM below threshold | NA | Upregulated in lichen | 0.25 | 29.38005 | 588 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_000470-T1 | pTM below threshold | NA | Non-DGE | 0.13 | 45.71574 | 216 | IPR031452 Protein Kre1 | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_000606-T1 | pTM below threshold | NA | Upregulated in lichen | 0.19 | 29.36423 | 267 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_000609-T1 | pTM below threshold | NA | Upregulated in lichen | 0.35 | 44.32490 | 149 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_000630-T1 | pTM below threshold | NA | Non-DGE | 0.38 | 58.03000 | 175 | IPR008427 Extracellular membrane protein, CFEM domain | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_000639-T1 | pTM below threshold | NA | Non-DGE | 0.29 | 59.62101 | 119 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_000655-T1 | pTM below threshold | NA | Upregulated in lichen | 0.43 | 40.92976 | 210 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_000697-T1 | pTM below threshold | NA | Upregulated in lichen | 0.23 | 40.31839 | 224 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_000700-T1 | pTM below threshold | NA | Non-DGE | 0.48 | 53.36772 | 346 | IPR036908 RlpA-like domain superfamily | NA | NA | Below pLDDT threshold | NA | NA | A0A4S9S5J9; Expansin-like EG45 domain-containing protein; Aureobasidium pullulans (Black yeast) (Pullularia pullulans); 1.557e-08 | A0A178CMY3; deleted; ; 1.304e-07 |
| XANPAGTX0501_000737-T1 | pTM below threshold | NA | Upregulated in lichen | 0.24 | 32.97850 | 341 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_000813-T1 | pTM below threshold | NA | Non-DGE | 0.38 | 45.56127 | 197 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_000953-T1 | pTM below threshold | NA | Non-DGE | 0.18 | 28.39448 | 201 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_001001-T1 | pTM below threshold | NA | Non-DGE | 0.2 | 57.35556 | 99 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_001042-T1 | pTM below threshold | NA | Non-DGE | 0.31 | 42.27669 | 142 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_001063-T1 | pTM below threshold | NA | Upregulated in lichen | 0.19 | 56.66084 | 131 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_001103-T1 | pTM below threshold | NA | Non-DGE | 0.16 | 51.99290 | 107 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_001136-T1 | pTM below threshold | NA | Non-DGE | 0.38 | 48.69567 | 1002 | IPR002889 Carbohydrate-binding WSC | AA2, AA5 | NA | Below pLDDT threshold | 5FWW; Wnt modulator Kremen in complex with DKK1 (CRD2) and LRP6 (PE3PE4); 1.155e-06 | 6SNW; Structure of Coxsackievirus A10 complexed with its receptor KREMEN1; 1.572e-06 | A0A1J9R4V4; Wsc-domain-containing protein; Diplodia corticola; 2.932e-19 | A0A3M7A6V9; WSC domain-containing protein; Hortaea werneckii; 1.006e-18 |
| XANPAGTX0501_001183-T1 | pTM below threshold | NA | Upregulated in lichen | 0.44 | 47.35611 | 126 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_001304-T1 | pTM below threshold | NA | Upregulated in lichen | 0.39 | 66.09179 | 78 | NA | NA | NA | Non-antimicrobial | NA | NA | NA | NA |
| XANPAGTX0501_001461-T1 | pTM below threshold | NA | Non-DGE | 0.28 | 36.83783 | 157 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_001550-T1 | pTM below threshold | NA | Non-DGE | 0.44 | 59.11496 | 276 | IPR002889 Carbohydrate-binding WSC | AA2, AA5 | NA | Below pLDDT threshold | 6SNW; Structure of Coxsackievirus A10 complexed with its receptor KREMEN1; 2.564e-08 | 5FWU; Wnt modulator Kremen crystal form II at 2.8A; 3.73e-08 | A0A2J6PEI4; Copper radical oxidase; Hyaloscypha hepaticicola; 4.812e-10 | A0A072PVC9; WSC domain-containing protein; Exophiala aquamarina CBS 119918; 5.804e-10 |
| XANPAGTX0501_001708-T1 | pTM below threshold | NA | Upregulated in lichen | 0.32 | 35.93536 | 222 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_001709-T1 | pTM below threshold | NA | Non-DGE | 0.31 | 37.15931 | 216 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_001849-T1 | pTM below threshold | NA | Non-DGE | 0.39 | 41.61976 | 207 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_001919-T1 | pTM below threshold | NA | Upregulated in lichen | 0.26 | 35.33512 | 203 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_001935-T1 | pTM below threshold | NA | Upregulated in lichen | 0.15 | 47.83888 | 170 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_002013-T1 | pTM below threshold | NA | Non-DGE | 0.16 | 49.99292 | 171 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_002041-T1 | pTM below threshold | NA | Upregulated in lichen | 0.32 | 38.90838 | 111 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_002086-T1 | pTM below threshold | NA | Non-DGE | 0.39 | 58.80412 | 204 | IPR008427 Extracellular membrane protein, CFEM domain | NA | NA | Below pLDDT threshold | NA | NA | A0A2V1B9P3; Extracellular membrane protein CFEM domain-containing protein; Cadophora sp. DSE1049; 4.966e-06 | A0A3D8QQ47; Extracellular membrane protein CFEM domain-containing protein; Coleophoma crateriformis; 3.307e-05 |
| XANPAGTX0501_002121-T1 | pTM below threshold | NA | Non-DGE | 0.21 | 30.50148 | 244 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_002186-T1 | pTM below threshold | NA | Upregulated in lichen | 0.17 | 44.08050 | 397 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_002220-T1 | pTM below threshold | NA | Non-DGE | 0.43 | 50.26500 | 1168 | IPR001223 Glycoside hydrolase family 18, catalytic domain;IPR001579 Glycosyl hydrolases family 18 (GH18) active site;IPR017853 Glycoside hydrolase superfamily | GH18 | NA | Below pLDDT threshold | 4TX6; AfChiA1 in complex with compound 1; 3.579e-40 | 2XUC; Natural product-guided discovery of a fungal chitinase inhibitor; 9.1e-36 | A0A5M8PFI4; chitinase (EC 3.2.1.14); Lasallia pustulata; 2.869e-51 | A0A2I0RWZ2; deleted; ; 2.694e-41 |
| XANPAGTX0501_002264-T1 | pTM below threshold | NA | Non-DGE | 0.45 | 54.44478 | 182 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_002336-T1 | pTM below threshold | NA | Non-DGE | 0.24 | 48.11919 | 236 | IPR000420 Yeast PIR protein repeat | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_002412-T1 | pTM below threshold | NA | Upregulated in lichen | 0.47 | 46.08050 | 440 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_002412-T2 | pTM below threshold | NA | Upregulated in lichen | 0.49 | 47.55088 | 431 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_002423-T1 | pTM below threshold | NA | Non-DGE | 0.45 | 67.76805 | 77 | NA | NA | NA | Non-antimicrobial | NA | NA | NA | NA |
| XANPAGTX0501_002446-T1 | pTM below threshold | NA | Upregulated in lichen | 0.28 | 52.93857 | 189 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_002482-T1 | pTM below threshold | NA | Non-DGE | 0.26 | 30.07165 | 248 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_002502-T1 | pTM below threshold | NA | Non-DGE | 0.45 | 44.87958 | 286 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_002514-T1 | pTM below threshold | NA | Upregulated in lichen | 0.2 | 56.13142 | 106 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_002565-T1 | pTM below threshold | NA | Upregulated in lichen | 0.29 | 48.51197 | 147 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_002660-T1 | pTM below threshold | NA | Non-DGE | 0.32 | 50.18997 | 309 | IPR000420 Yeast PIR protein repeat | NA | NA | Below pLDDT threshold | NA | NA | A0A2K0WBY6; Uncharacterized protein; Gibberella nygamai (Bean root rot disease fungus) (Fusarium nygamai); 2.916e-05 | A0A0F2MMU3; Uncharacterized protein; Sporothrix schenckii 1099-18; 4.904e-05 |
| XANPAGTX0501_002665-T1 | pTM below threshold | NA | Upregulated in lichen | 0.35 | 40.79893 | 280 | IPR024079 Metallopeptidase, catalytic domain superfamily | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_002697-T1 | pTM below threshold | NA | Non-DGE | 0.38 | 54.53519 | 154 | NA | GH128 | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_002844-T1 | pTM below threshold | NA | Non-DGE | 0.42 | 60.30492 | 177 | IPR008427 Extracellular membrane protein, CFEM domain | NA | NA | Below pLDDT threshold | NA | NA | A0A6A6WBS8; Extracellular membrane protein CFEM domain-containing protein; Pseudovirgaria hyperparasitica; 7.371e-05 | A0A4S8UDR1; WSC domain-containing protein; Aureobasidium pullulans (Black yeast) (Pullularia pullulans); 0.0002121 |
| XANPAGTX0501_003040-T1 | pTM below threshold | NA | Non-DGE | 0.35 | 55.21358 | 296 | IPR008427 Extracellular membrane protein, CFEM domain | NA | NA | Below pLDDT threshold | NA | NA | A0A178CLW4; Extracellular membrane protein CFEM domain-containing protein; Fonsecaea nubica; 2.395e-05 | A0A0D2AVK1; Extracellular membrane protein CFEM domain-containing protein; Exophiala spinifera; 0.0001056 |
| XANPAGTX0501_003231-T1 | pTM below threshold | NA | Non-DGE | 0.37 | 46.96308 | 211 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_003232-T1 | pTM below threshold | NA | Non-DGE | 0.19 | 42.98057 | 105 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_003233-T1 | pTM below threshold | NA | Non-DGE | 0.37 | 47.58521 | 192 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_003270-T1 | pTM below threshold | NA | Upregulated in lichen | 0.23 | 36.12173 | 231 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_003314-T1 | pTM below threshold | NA | Non-DGE | 0.27 | 48.61361 | 97 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_003361-T1 | pTM below threshold | NA | Upregulated in lichen | 0.44 | 51.78166 | 500 | NA | NA | NA | Below pLDDT threshold | NA | NA | A0A6H0XNU9; Uncharacterized protein; Peltaster fructicola; 1.513e-18 | J3KK77; Uncharacterized protein; Coccidioides immitis (strain RS) (Valley fever fungus); 2.67e-18 |
| XANPAGTX0501_003362-T1 | pTM below threshold | NA | Non-DGE | 0.19 | 31.78513 | 955 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_003435-T1 | pTM below threshold | NA | Non-DGE | 0.32 | 47.97649 | 606 | NA | NA | NA | Below pLDDT threshold | NA | NA | A0A1W5DE84; glutathione transferase (EC 2.5.1.18); Lasallia pustulata; 3.128e-09 | U4LRI5; Carbohydrate-binding module family 19 domain-containing protein; Pyronema omphalodes (strain CBS 100304) (Pyronema confluens); 1.09e-07 |
| XANPAGTX0501_003436-T1 | pTM below threshold | NA | Non-DGE | 0.48 | 74.36984 | 190 | NA | NA | NA | Antimicrobial | NA | NA | A0A1B8D8I3; Biotrophy-associated secreted protein 2; Pseudogymnoascus sp. 24MN13; 2.363e-19 | A0A094CVI4; Biotrophy-associated secreted protein 2; Pseudogymnoascus sp. VKM F-4515 (FW-2607); 2.429e-18 |
| XANPAGTX0501_003606-T1 | pTM below threshold | NA | Upregulated in lichen | 0.29 | 34.10482 | 197 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_003677-T1 | pTM below threshold | NA | Non-DGE | 0.27 | 30.55640 | 197 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_003679-T1 | pTM below threshold | NA | Non-DGE | 0.46 | 49.80288 | 560 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_003725-T1 | pTM below threshold | NA | Non-DGE | 0.25 | 48.07547 | 1001 | NA | NA | NA | Below pLDDT threshold | NA | NA | A0A093ZSQ2; F-box domain-containing protein; Pseudogymnoascus sp. VKM F-3775; 9.192e-06 | A0A6A5K0Q4; Uncharacterized protein; Decorospora gaudefroyi; 5.299e-05 |
| XANPAGTX0501_003765-T1 | pTM below threshold | NA | Upregulated in lichen | 0.17 | 36.25006 | 350 | IPR000420 Yeast PIR protein repeat | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_003766-T1 | pTM below threshold | NA | Upregulated in lichen | 0.35 | 47.00045 | 177 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_003769-T1 | pTM below threshold | NA | Non-DGE | 0.38 | 84.30392 | 51 | NA | NA | NA | Non-antimicrobial | NA | NA | NA | NA |
| XANPAGTX0501_003850-T1 | pTM below threshold | NA | Upregulated in culture | 0.29 | 38.25145 | 304 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_003863-T2 | pTM below threshold | NA | Upregulated in culture | 0.39 | 50.59582 | 340 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_003865-T1 | pTM below threshold | NA | Non-DGE | 0.24 | 32.08215 | 247 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_003880-T1 | pTM below threshold | NA | Non-DGE | 0.41 | 54.98441 | 281 | NA | NA | NA | Below pLDDT threshold | NA | NA | A0A6A6HBS6; AA1-like domain-containing protein; Viridothelium virens; 0.000714 | NA |
| XANPAGTX0501_003978-T1 | pTM below threshold | NA | Non-DGE | 0.16 | 46.38479 | 240 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_003988-T1 | pTM below threshold | NA | Non-DGE | 0.48 | 52.03327 | 844 | IPR008427 Extracellular membrane protein, CFEM domain | NA | NA | Below pLDDT threshold | NA | NA | A0A6A6HF69; Extracellular membrane protein CFEM domain-containing protein; Viridothelium virens; 4.525e-25 | A0A0A1TKI7; Putative Beta-1,3-endoglucanase; [Torrubiella] hemipterigena; 4.406e-23 |
| XANPAGTX0501_004023-T1 | pTM below threshold | NA | Non-DGE | 0.23 | 40.82680 | 222 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_004085-T1 | pTM below threshold | NA | Non-DGE | 0.27 | 34.75723 | 697 | IPR000420 Yeast PIR protein repeat | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_004226-T1 | pTM below threshold | NA | Non-DGE | 0.33 | 48.76878 | 1218 | NA | NA | NA | Below pLDDT threshold | NA | NA | A0A0F7U4N9; Uncharacterized protein; Penicillium brasilianum; 1.716e-15 | A0A4Z0Z4R1; Uncharacterized protein; Xylaria hypoxylon; 2.608e-10 |
| XANPAGTX0501_004309-T1 | pTM below threshold | NA | Upregulated in lichen | 0.28 | 55.95350 | 80 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_004507-T1 | pTM below threshold | NA | Non-DGE | 0.49 | 60.31919 | 295 | IPR008427 Extracellular membrane protein, CFEM domain | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_004636-T1 | pTM below threshold | NA | Non-DGE | 0.26 | 41.79605 | 693 | NA | NA | NA | Below pLDDT threshold | NA | NA | A0A6G1HAL2; Apple domain-containing protein; Aulographum hederae CBS 113979; 8.048e-07 | A0A4V4K3D9; feruloyl esterase (EC 3.1.1.73); Aureobasidium pullulans (Black yeast) (Pullularia pullulans); 1.935e-06 |
| XANPAGTX0501_004671-T1 | pTM below threshold | NA | Non-DGE | 0.33 | 40.73679 | 187 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_004880-T1 | pTM below threshold | NA | Upregulated in lichen | 0.2 | 46.83578 | 199 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_004881-T1 | pTM below threshold | NA | Upregulated in lichen | 0.17 | 31.09336 | 447 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_004930-T1 | pTM below threshold | NA | Upregulated in lichen | 0.19 | 42.19248 | 137 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_004931-T1 | pTM below threshold | NA | Non-DGE | 0.25 | 56.26977 | 214 | NA | NA | NA | Below pLDDT threshold | NA | NA | M3D3T5; Uncharacterized protein; Sphaerulina musiva (strain SO2202) (Poplar stem canker fungus) (Septoria musiva); 0.0001561 | A0A1P8YXY7; Uncharacterized protein; Passalora fulva (Tomato leaf mold) (Cladosporium fulvum); 0.0002854 |
| XANPAGTX0501_004978-T1 | pTM below threshold | NA | Upregulated in lichen | 0.18 | 38.53014 | 212 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_005046-T1 | pTM below threshold | NA | Non-DGE | 0.3 | 33.33182 | 231 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_005093-T1 | pTM below threshold | NA | Non-DGE | 0.43 | 73.20231 | 117 | IPR011024 Gamma-crystallin-like | NA | NA | Non-antimicrobial | NA | NA | A0A135TVW9; Uncharacterized protein; Colletotrichum nymphaeae SA-01; 4.513e-05 | A0A2T2PBH5; Beta/gamma crystallin ‘Greek key’ domain-containing protein; Corynespora cassiicola Philippines; 0.0001914 |
| XANPAGTX0501_005317-T1 | pTM below threshold | NA | Upregulated in lichen | 0.29 | 35.48320 | 334 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_005338-T1 | pTM below threshold | NA | Non-DGE | 0.3 | 42.89314 | 299 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_005364-T1 | pTM below threshold | NA | Upregulated in lichen | 0.35 | 59.45167 | 102 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_005536-T1 | pTM below threshold | NA | Non-DGE | 0.11 | 43.11011 | 180 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_005573-T1 | pTM below threshold | NA | Upregulated in lichen | 0.27 | 41.92369 | 244 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_005653-T1 | pTM below threshold | NA | Non-DGE | 0.27 | 35.34574 | 289 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_005717-T1 | pTM below threshold | NA | Upregulated in lichen | 0.35 | 35.15150 | 213 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_005718-T1 | pTM below threshold | NA | Non-DGE | 0.2 | 33.49452 | 292 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_005733-T1 | pTM below threshold | NA | Upregulated in lichen | 0.2 | 28.61554 | 350 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_005759-T1 | pTM below threshold | NA | Upregulated in culture | 0.37 | 60.31197 | 218 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_005792-T1 | pTM below threshold | NA | Non-DGE | 0.32 | 75.71431 | 534 | IPR018392 LysM domain;IPR036779 LysM domain superfamily | CBM50 | NA | Antimicrobial | 4B9H; Cladosporium fulvum LysM effector Ecp6 in complex with a beta-1,4- linked N-acetyl-D-glucosamine tetramer: I3C heavy atom derivative; 7.082e-05 | NA | A0A0C2IKZ1; LysM domain-containing protein; Sporothrix brasiliensis 5110; 1.409e-38 | U7PMK7; LysM domain-containing protein; Sporothrix schenckii (strain ATCC 58251 / de Perez 2211183) (Rose-picker’s disease fungus); 8.377e-38 |
| XANPAGTX0501_005813-T1 | pTM below threshold | NA | Non-DGE | 0.43 | 62.54160 | 288 | IPR018466 Yeast cell wall synthesis Kre9/Knh1-like, N-terminal | NA | NA | Below pLDDT threshold | NA | NA | A0A443I375; GPI anchored serine-threonine rich protein; Byssochlamys spectabilis (Paecilomyces variotii); 1.373e-13 | A0A2T2NIQ0; Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein; Corynespora cassiicola Philippines; 8.064e-13 |
| XANPAGTX0501_005845-T1 | pTM below threshold | NA | Non-DGE | 0.3 | 55.95631 | 931 | IPR002889 Carbohydrate-binding WSC | AA2, AA5 | NA | Below pLDDT threshold | 5I25; human recombinant coagulation FXI in complex with a peptide derived from human high molecular weight kininogen (HKP); 5.622e-10 | 5EOK; Human Plasma Coagulation Factor XI in complex with peptide P39; 7.873e-10 | A0A6A6YV25; Apple domain-containing protein; Mytilinidion resinicola; 1.527e-20 | A0A0D2CZ88; Apple domain-containing protein; Exophiala xenobiotica; 7.741e-18 |
| XANPAGTX0501_005926-T1 | pTM below threshold | NA | Non-DGE | 0.31 | 36.87731 | 212 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_006010-T1 | pTM below threshold | NA | Non-DGE | 0.26 | 41.65388 | 224 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_006091-T1 | pTM below threshold | NA | Upregulated in culture | 0.37 | 59.93578 | 296 | NA | NA | NA | Below pLDDT threshold | NA | NA | A0A0D2G7D5; Extracellular membrane protein CFEM domain-containing protein; Fonsecaea pedrosoi CBS 271.37; 6.802e-05 | A0A0D2CC38; Extracellular membrane protein CFEM domain-containing protein; Cladophialophora immunda; 0.0001483 |
| XANPAGTX0501_006135-T1 | pTM below threshold | NA | Non-DGE | 0.21 | 44.10064 | 344 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_006144-T1 | pTM below threshold | NA | Non-DGE | 0.29 | 29.79741 | 355 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_006188-T1 | pTM below threshold | NA | Non-DGE | 0.4 | 45.56256 | 641 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_006200-T1 | pTM below threshold | NA | Non-DGE | 0.22 | 38.86053 | 375 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_006216-T1 | pTM below threshold | NA | Non-DGE | 0.45 | 74.14030 | 164 | NA | NA | NA | Antimicrobial | NA | NA | A0A6A6RAX6; EGF-like domain-containing protein; Lophium mytilinum; 9.832e-07 | NA |
| XANPAGTX0501_006245-T1 | pTM below threshold | NA | Upregulated in lichen | 0.38 | 40.98643 | 224 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_006269-T1 | pTM below threshold | NA | Non-DGE | 0.35 | 36.31963 | 217 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_006277-T1 | pTM below threshold | NA | Non-DGE | 0.22 | 34.49871 | 202 | IPR004212 GTF2I-like repeat | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_006282-T1 | pTM below threshold | NA | Upregulated in lichen | 0.29 | 37.07552 | 212 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_006327-T1 | pTM below threshold | NA | Upregulated in lichen | 0.39 | 52.12547 | 311 | IPR018466 Yeast cell wall synthesis Kre9/Knh1-like, N-terminal | NA | NA | Below pLDDT threshold | NA | NA | A0A0D1ZSJ7; Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein; Exophiala mesophila (Black yeast); 5.571e-07 | A0A0F8V2U6; Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein; Aspergillus ochraceoroseus; 3.566e-06 |
| XANPAGTX0501_006345-T1 | pTM below threshold | NA | Non-DGE | 0.26 | 41.90220 | 141 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_006386-T1 | pTM below threshold | NA | Upregulated in culture | 0.39 | 47.84989 | 445 | NA | NA | NA | Below pLDDT threshold | NA | NA | A0A1B9G3W8; Uncharacterized protein; Kwoniella bestiolae CBS 10118; 1.331e-07 | A0A1A6AB64; Uncharacterized protein; Kwoniella dejecticola CBS 10117; 1.91e-07 |
| XANPAGTX0501_006396-T1 | pTM below threshold | NA | Non-DGE | 0.28 | 38.38777 | 247 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_006430-T1 | pTM below threshold | NA | Non-DGE | 0.4 | 58.62042 | 526 | NA | NA | NA | Below pLDDT threshold | NA | NA | C9SCF8; Predicted protein; Verticillium alfalfae (strain VaMs.102 / ATCC MYA-4576 / FGSC 10136) (Verticillium wilt of alfalfa) (Verticillium albo-atrum); 3.233e-15 | A0A507BM56; Uncharacterized protein; Thyridium curvatum; 6.992e-15 |
| XANPAGTX0501_006469-T1 | pTM below threshold | NA | Non-DGE | 0.43 | 42.74056 | 214 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_006612-T1 | pTM below threshold | NA | Non-DGE | 0.33 | 41.95192 | 291 | IPR036779 LysM domain superfamily | NA | NA | Below pLDDT threshold | NA | NA | A0A0J8RMW3; LysM domain-containing protein; Coccidioides immitis H538.4; 5.611e-08 | E9DDV5; LysM domain-containing protein; Coccidioides posadasii (strain RMSCC 757 / Silveira) (Valley fever fungus); 1.291e-07 |
| XANPAGTX0501_006642-T1 | pTM below threshold | NA | Non-DGE | 0.23 | 50.69881 | 210 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_006751-T1 | pTM below threshold | NA | Upregulated in lichen | 0.25 | 29.51219 | 237 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_006771-T1 | pTM below threshold | NA | Non-DGE | 0.25 | 45.20033 | 122 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_006846-T1 | pTM below threshold | NA | Upregulated in lichen | 0.39 | 60.82377 | 106 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_006848-T1 | pTM below threshold | NA | Upregulated in culture | 0.18 | 56.75794 | 107 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_006860-T1 | pTM below threshold | NA | Upregulated in lichen | 0.49 | 60.95872 | 321 | IPR008979 Galactose-binding-like domain superfamily | NA | NA | Below pLDDT threshold | 5W6H; Crystal structure of Bacteriophage CBA120 tailspike protein 4 enzymatically active domain (TSP4dN, orf213); 2.258e-06 | 5X7S; Crystal structure of Paenibacillus sp. 598K alpha-1,6-glucosyltransferase, terbium derivative; 2.023e-05 | A0A6A6YIM7; CBM-cenC domain-containing protein; Mytilinidion resinicola; 8.037e-07 | A0A5E4KIN1; Uncharacterized protein; Uncultured archaeon; 3.342e-06 |
| XANPAGTX0501_006870-T1 | pTM below threshold | NA | Non-DGE | 0.25 | 49.69147 | 347 | IPR018909 Endo-1,3(4)-beta-glucanase 1, carbohydrate binding | CBM52 | NA | Below pLDDT threshold | NA | NA | R7YMC8; Endo-1,3(4)-beta-glucanase 1 carbohydrate binding domain-containing protein; Coniosporium apollinis (strain CBS 100218) (Rock-inhabiting black yeast); 1.193e-05 | A0A1S9RPI8; Endo-1,3(4)-beta-glucanase 1 carbohydrate binding domain-containing protein; Penicillium brasilianum; 2.619e-05 |
| XANPAGTX0501_006878-T1 | pTM below threshold | NA | Non-DGE | 0.48 | 55.66750 | 184 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_006927-T1 | pTM below threshold | NA | Non-DGE | 0.29 | 39.10967 | 182 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_007125-T1 | pTM below threshold | NA | Non-DGE | 0.31 | 37.96095 | 315 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_007184-T1 | pTM below threshold | NA | Non-DGE | 0.27 | 35.92510 | 204 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_007194-T1 | pTM below threshold | NA | Non-DGE | 0.4 | 52.33116 | 147 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_007362-T1 | pTM below threshold | NA | Upregulated in lichen | 0.27 | 33.91120 | 392 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_007451-T1 | pTM below threshold | NA | Non-DGE | 0.35 | 45.09716 | 155 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_007556-T1 | pTM below threshold | NA | Non-DGE | 0.32 | 42.12523 | 128 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_007596-T1 | pTM below threshold | NA | Non-DGE | 0.32 | 52.98769 | 471 | NA | NA | NA | Below pLDDT threshold | NA | NA | A0A0D8JU73; GPI anchored protein; Coccidioides immitis (strain RS) (Valley fever fungus); 1.668e-13 | A0A117NP65; Uncharacterized protein; Penicillium freii; 9.925e-13 |
| XANPAGTX0501_007662-T1 | pTM below threshold | NA | Non-DGE | 0.41 | 67.45495 | 303 | IPR036908 RlpA-like domain superfamily | NA | NA | Non-antimicrobial | 5NTB; Streptomyces papain inhibitor (SPI); 6.385e-12 | 4L48; Crystal structure of d78n mutant clavibacter michiganensis expansin in complex with cellohexaose; 3.418e-06 | A0A094D7Z3; RlpA-like protein double-psi beta-barrel domain-containing protein; Pseudogymnoascus sp. VKM F-4515 (FW-2607); 1.021e-16 | K1XV49; Riboflavin aldehyde-forming enzyme; Marssonina brunnea f. sp. multigermtubi (strain MB_m1) (Marssonina leaf spot fungus); 5.927e-16 |
| XANPAGTX0501_007855-T1 | pTM below threshold | NA | Non-DGE | 0.44 | 55.95904 | 114 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_007865-T1 | pTM below threshold | NA | Upregulated in lichen | 0.2 | 34.63703 | 209 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_007939-T1 | pTM below threshold | NA | Upregulated in lichen | 0.39 | 38.59798 | 258 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_007940-T1 | pTM below threshold | NA | Non-DGE | 0.35 | 41.71245 | 220 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_008019-T1 | pTM below threshold | NA | Upregulated in lichen | 0.43 | 46.04617 | 227 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_008041-T1 | pTM below threshold | NA | Upregulated in lichen | 0.27 | 33.06829 | 287 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_008135-T1 | pTM below threshold | NA | Non-DGE | 0.29 | 48.80956 | 228 | NA | NA | NA | Below pLDDT threshold | NA | NA | A0A167V6T8; Uncharacterized protein; Ascosphaera apis ARSEF 7405; 0.0008161 | NA |
| XANPAGTX0501_008148-T1 | pTM below threshold | NA | Non-DGE | 0.25 | 36.09338 | 717 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_008162-T1 | pTM below threshold | NA | Non-DGE | 0.2 | 35.30811 | 286 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_008182-T1 | pTM below threshold | NA | Non-DGE | 0.35 | 47.60920 | 125 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_008186-T1 | pTM below threshold | NA | Non-DGE | 0.46 | 58.11869 | 374 | IPR008972 Cupredoxin | NA | NA | Below pLDDT threshold | 3CVD; Regulation of Protein Function: Crystal Packing Interfaces and Conformational Dimerization; 9.21e-06 | 2W88; Plastocyanin variant with N-terminal Methionine - open structure; 9.776e-06 | C4JT37; Phytocyanin domain-containing protein; Uncinocarpus reesii (strain UAMH 1704); 2.287e-22 | A0A0C3HWR8; Phytocyanin domain-containing protein; Oidiodendron maius (strain Zn); 3.911e-22 |
| XANPAGTX0501_008218-T1 | pTM below threshold | NA | Non-DGE | 0.46 | 46.12536 | 418 | IPR024079 Metallopeptidase, catalytic domain superfamily | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_008219-T1 | pTM below threshold | NA | Non-DGE | 0.49 | 59.06300 | 290 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_008281-T1 | pTM below threshold | NA | Non-DGE | 0.32 | 44.73137 | 161 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_008351-T1 | pTM below threshold | NA | Non-DGE | 0.47 | 73.50206 | 559 | NA | NA | NA | Antimicrobial | NA | NA | A0A094A2F5; Uncharacterized protein; Pseudogymnoascus sp. VKM F-4281 (FW-2241); 3.078e-37 | A0A284RFH5; Related to cell wall mannoprotein; Armillaria ostoyae (Armillaria root rot fungus); 3.704e-33 |
| XANPAGTX0501_008400-T1 | pTM below threshold | NA | Non-DGE | 0.44 | 63.87267 | 262 | IPR018466 Yeast cell wall synthesis Kre9/Knh1-like, N-terminal | NA | NA | Below pLDDT threshold | NA | NA | A0A6G1HP33; Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein; Trichodelitschia bisporula; 5.099e-11 | A0A6C1LWC6; deleted; ; 5.704e-11 |
| XANPAGTX0501_008424-T1 | pTM below threshold | NA | Non-DGE | 0.47 | 67.70070 | 229 | IPR018466 Yeast cell wall synthesis Kre9/Knh1-like, N-terminal | NA | NA | Non-antimicrobial | 7XT6; Structure of a membrane protein M3; 0.0008373 | NA | R7YRL3; Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein; Coniosporium apollinis (strain CBS 100218) (Rock-inhabiting black yeast); 8.236e-12 | A0A6G1H9J1; Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein; Aulographum hederae CBS 113979; 8.236e-12 |
| XANPAGTX0501_008443-T1 | pTM below threshold | NA | Non-DGE | 0.42 | 65.45769 | 744 | IPR002889 Carbohydrate-binding WSC | AA2, AA5 | NA | Antimicrobial | 5FWW; Wnt modulator Kremen in complex with DKK1 (CRD2) and LRP6 (PE3PE4); 3.046e-06 | 7PZ2; Structure of the mechanosensor domain of Wsc1 from Saccharomyces cerevisiae; 0.0001756 | A0A1Q8RZZ8; WSC domain-containing protein-like protein 4; Colletotrichum chlorophyti; 2.882e-49 | G0RCZ5; N-terminal WSC domain-containing protein; Hypocrea jecorina (strain QM6a) (Trichoderma reesei); 2.272e-38 |
| XANPAGTX0501_008477-T1 | pTM below threshold | NA | Non-DGE | 0.34 | 38.65885 | 183 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_008519-T1 | pTM below threshold | NA | Non-DGE | 0.42 | 50.80404 | 1065 | NA | NA | NA | Below pLDDT threshold | NA | NA | A0A139H0H7; Chitin-binding type-1 domain-containing protein; Pseudocercospora eumusae; 2.429e-16 | M3AJY5; Apple domain-containing protein; Pseudocercospora fijiensis (strain CIRAD86) (Black leaf streak disease fungus) (Mycosphaerella fijiensis); 5.071e-15 |
| XANPAGTX0501_008553-T1 | pTM below threshold | NA | Non-DGE | 0.21 | 35.48684 | 779 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_008622-T1 | pTM below threshold | NA | Upregulated in lichen | 0.27 | 36.45940 | 184 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_008694-T1 | pTM below threshold | NA | Non-DGE | 0.22 | 40.74125 | 265 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_008809-T1 | pTM below threshold | NA | Non-DGE | 0.31 | 45.66059 | 488 | NA | NA | NA | Below pLDDT threshold | NA | NA | A0A4S8SXU7; feruloyl esterase (EC 3.1.1.73); Aureobasidium pullulans (Black yeast) (Pullularia pullulans); 2.438e-06 | A0A4S9HI98; feruloyl esterase (EC 3.1.1.73); Aureobasidium pullulans (Black yeast) (Pullularia pullulans); 3.099e-06 |
| XANPAGTX0501_008872-T1 | pTM below threshold | NA | Non-DGE | 0.35 | 34.38388 | 201 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_008875-T1 | pTM below threshold | NA | Upregulated in lichen | 0.25 | 36.22508 | 128 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_008931-T1 | pTM below threshold | NA | Non-DGE | 0.19 | 44.85339 | 221 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_008948-T1 | pTM below threshold | NA | Non-DGE | 0.17 | 38.85130 | 231 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_008971-T1 | pTM below threshold | NA | Non-DGE | 0.41 | 44.89566 | 316 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_008978-T1 | pTM below threshold | NA | Upregulated in lichen | 0.27 | 39.13834 | 193 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_008987-T1 | pTM below threshold | NA | Non-DGE | 0.28 | 39.11374 | 171 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_009011-T1 | pTM below threshold | NA | Upregulated in lichen | 0.2 | 56.92495 | 99 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_009191-T1 | pTM below threshold | NA | Non-DGE | 0.48 | 59.44738 | 122 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_009292-T1 | pTM below threshold | NA | Non-DGE | 0.49 | 45.18802 | 333 | NA | NA | NA | Below pLDDT threshold | NA | NA | A0A4Q4R4H3; deleted; ; 2.317e-07 | A0A7U2F0M6; Uncharacterized protein; Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Parastagonospora nodorum); 2.943e-06 |
| XANPAGTX0501_009295-T1 | pTM below threshold | NA | Non-DGE | 0.47 | 52.70230 | 721 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_009312-T1 | pTM below threshold | NA | Non-DGE | 0.45 | 48.78964 | 966 | IPR000757 Glycoside hydrolase family 16;IPR013320 Concanavalin A-like lectin/glucanase domain superfamily | GH16 | NA | Below pLDDT threshold | 6IBW; Crh5 transglycosylase in complex with NAG; 7.599e-33 | 6IBU; Apo Crh5 transglycosylase; 1.787e-32 | A0A0S6XEC7; GH16 domain-containing protein; Fungal sp. (strain No.11243); 1.298e-33 | A0A4V3UP95; Glycosidase (EC 3.2.-.-); Aspergillus tanneri; 7.181e-33 |
| XANPAGTX0501_009324-T1 | pTM below threshold | NA | Non-DGE | 0.18 | 55.03943 | 87 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_009430-T1 | pTM below threshold | NA | Non-DGE | 0.29 | 51.23665 | 251 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_009502-T1 | pTM below threshold | NA | Non-DGE | 0.14 | 51.21467 | 150 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_009607-T1 | pTM below threshold | NA | Upregulated in lichen | 0.32 | 33.84773 | 309 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_009615-T1 | pTM below threshold | NA | Upregulated in lichen | 0.32 | 65.99257 | 113 | IPR035940 CAP superfamily | NA | NA | Non-antimicrobial | NA | NA | NA | NA |
| XANPAGTX0501_009668-T1 | pTM below threshold | NA | Upregulated in lichen | 0.24 | 62.61028 | 212 | NA | NA | NA | Below pLDDT threshold | NA | NA | H6C1Q2; Uncharacterized protein; Exophiala dermatitidis (strain ATCC 34100 / CBS 525.76 / NIH/UT8656) (Black yeast) (Wangiella dermatitidis); 3.367e-07 | A0A366S4S1; Uncharacterized protein; Fusarium coffeatum; 2.219e-06 |
| XANPAGTX0501_009682-T1 | pTM below threshold | NA | Non-DGE | 0.39 | 39.61619 | 236 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_009683-T1 | pTM below threshold | NA | Upregulated in lichen | 0.24 | 30.44388 | 428 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_009688-T1 | pTM below threshold | NA | Upregulated in lichen | 0.24 | 49.57690 | 290 | IPR000254 Cellulose-binding domain, fungal;IPR035971 Cellulose-binding domain superfamily;IPR036908 RlpA-like domain superfamily | NA | NA | Below pLDDT threshold | 4QI4; Dehydrogenase domain of Myriococcum thermophilum cellobiose dehydrogenase, MtDH; 0.0006969 | NA | N4X993; Endo-beta-1,4-glucanase D (Endoglucanase D) (EC 3.2.1.4) (Carboxymethylcellulase D) (Cellulase D); Cochliobolus heterostrophus (strain C4 / ATCC 48331 / race T) (Southern corn leaf blight fungus) (Bipolaris maydis); 0.0007107 | NA |
| XANPAGTX0501_009689-T1 | pTM below threshold | NA | Upregulated in lichen | 0.31 | 41.64505 | 222 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_009692-T1 | pTM below threshold | NA | Non-DGE | 0.3 | 42.07158 | 215 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_009726-T1 | pTM below threshold | NA | Non-DGE | 0.23 | 48.70371 | 124 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_009730-T1 | pTM below threshold | NA | Upregulated in lichen | 0.28 | 47.45514 | 255 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_009793-T1 | pTM below threshold | NA | Non-DGE | 0.21 | 35.83401 | 207 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_009844-T1 | pTM below threshold | NA | Non-DGE | 0.38 | 37.60851 | 241 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_009857-T1 | pTM below threshold | NA | Non-DGE | 0.49 | 52.14888 | 179 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_009886-T1 | pTM below threshold | NA | Upregulated in lichen | 0.2 | 40.27393 | 112 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_009899-T1 | pTM below threshold | NA | Non-DGE | 0.19 | 35.46123 | 203 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_009901-T1 | pTM below threshold | NA | Non-DGE | 0.23 | 32.99650 | 180 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_009962-T1 | pTM below threshold | NA | Upregulated in culture | 0.45 | 57.73133 | 294 | NA | NA | NA | Below pLDDT threshold | NA | NA | A0A2T4A4W1; Apple domain-containing protein; Trichoderma harzianum CBS 226.95; 0.0007207 | NA |
| XANPAGTX0501_010021-T1 | pTM below threshold | NA | Upregulated in lichen | 0.15 | 39.63054 | 224 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_010022-T1 | pTM below threshold | NA | Upregulated in lichen | 0.2 | 40.20379 | 116 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_010026-T1 | pTM below threshold | NA | Upregulated in lichen | 0.36 | 50.82466 | 371 | IPR018392 LysM domain;IPR036779 LysM domain superfamily | NA | NA | Below pLDDT threshold | NA | NA | A0A6G1ML62; Uncharacterized protein; Orbilia oligospora (Nematode-trapping fungus) (Arthrobotrys oligospora); 4.647e-09 | A0A7C8K1K9; LysM domain-containing protein; Orbilia oligospora (Nematode-trapping fungus) (Arthrobotrys oligospora); 1.75e-08 |
| XANPAGTX0501_010040-T1 | pTM below threshold | NA | Upregulated in lichen | 0.42 | 52.91466 | 290 | NA | NA | NA | Below pLDDT threshold | NA | NA | A0A1B8AR82; Uncharacterized protein; Fusarium poae; 5.417e-07 | A0A136ISV8; Uncharacterized protein; Microdochium bolleyi; 1.31e-06 |
| XANPAGTX0501_010086-T1 | pTM below threshold | NA | Non-DGE | 0.17 | 55.87331 | 151 | IPR000420 Yeast PIR protein repeat | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_010088-T1 | pTM below threshold | NA | Non-DGE | 0.45 | 59.31449 | 312 | NA | NA | NA | Below pLDDT threshold | NA | NA | Q2HDI8; Uncharacterized protein; Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970) (Soil fungus); 1.063e-13 | A0A0D1XIR7; Uncharacterized protein; Verruconis gallopava; 2.728e-13 |
| XANPAGTX0501_010096-T1 | pTM below threshold | NA | Non-DGE | 0.25 | 41.67990 | 292 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_010127-T1 | pTM below threshold | NA | Non-DGE | 0.43 | 67.28046 | 87 | NA | NA | NA | Non-antimicrobial | NA | NA | NA | NA |
| XANPAGTX0501_010138-T1 | pTM below threshold | NA | Non-DGE | 0.11 | 41.18544 | 204 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_010307-T1 | pTM below threshold | NA | Upregulated in culture | 0.26 | 29.37579 | 356 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_010329-T1 | pTM below threshold | NA | Non-DGE | 0.23 | 55.70355 | 107 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_010382-T1 | pTM below threshold | NA | Non-DGE | 0.3 | 37.89519 | 833 | NA | NA | NA | Below pLDDT threshold | NA | NA | A0A066X6J5; Putative alpha-1,3-glucanase; Colletotrichum sublineola (Sorghum anthracnose fungus); 5.117e-11 | A0A4S9I1D4; Uncharacterized protein; Aureobasidium pullulans (Black yeast) (Pullularia pullulans); 1.349e-10 |
| XANPAGTX0501_010393-T1 | pTM below threshold | NA | Upregulated in culture | 0.36 | 68.70766 | 209 | NA | NA | NA | Non-antimicrobial | NA | NA | NA | NA |
| XANPAGTX0501_010394-T1 | pTM below threshold | NA | Non-DGE | 0.29 | 42.73618 | 173 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_010595-T1 | pTM below threshold | NA | Non-DGE | 0.25 | 31.68788 | 170 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_010636-T1 | pTM below threshold | NA | Non-DGE | 0.2 | 30.96896 | 279 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_010737-T1 | pTM below threshold | NA | Non-DGE | 0.49 | 47.04299 | 354 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
| XANPAGTX0501_010738-T1 | pTM below threshold | NA | Non-DGE | 0.48 | 50.86233 | 356 | NA | NA | NA | Below pLDDT threshold | NA | NA | NA | NA |
analysis_and_temp_files/05_cluster_structures/lddt_tree_itol.nwk.txtresults/cluster_tree/clusters.*library(RColorBrewer)
#define palette
get_11_colors<-function(color){ # a function for each color gives 11 shades from dark to light as a dataframe with one row
colfunc1 <- colorRampPalette(c("black", color))
colfunc2 <- colorRampPalette(c(color,"white"))
darks<-colfunc1(10)[7:10]
lights<-colfunc2(10)[2:8]
return(c(darks,lights))
}
l<-lapply(brewer.pal(8,"Dark2"),get_11_colors)
color_table<-do.call(rbind,l)
color_table<-data.frame(color_table)
color_table$hue<-brewer.pal(8,"Dark2")
color_list<-color_table %>% pivot_longer(-hue,names_to="shade",values_to = "color") %>%
mutate(shade2 = case_when(shade=="X10"~"XX10",shade=="X11"~"XX11",T~shade)) %>% arrange(shade2) %>% select(color)
#add pallet to the cluster list
cluster_info_col<-cbind(cluster_info,color_list[1:84,])
#get common ancestors for all clades
itol_tree<-makeNodeLabel(lddt)
write.tree(itol_tree,"../analysis_and_temp_files/05_cluster_structures/lddt_tree_itol.nwk")
get_clade_node<-function(cluster,tree="itol_tree"){
tips<-clusters_df$tip[clusters_df$cluster_id==cluster]
mrsa_node<-findMRCA(itol_tree,tips,type="node")
node<-itol_tree$node.label[mrsa_node - length(itol_tree$tip.label)]
return(node)
}
cluster_info_col$node<-sapply(cluster_info_col$cluster_id,get_clade_node)
#had to manually assign the node for cl42 (the one that has 1 protein only)
cluster_info_col$node[cluster_info_col$cluster_id=="cl42"]<-clusters_df$tip[clusters_df$cluster_id=="cl42"]
cluster_info_col$node<-unlist(cluster_info_col$node)
write.table(cluster_info_col,"../analysis_and_temp_files/05_cluster_structures/cluster_col.txt",sep=",",quote = F, row.names = F, col.names=T)
#prepare the dataset
cat("DATASET_RANGE\nSEPARATOR COMMA\nDATASET_LABEL,Cluster\nRANGE_COVER,clade\nDATA\n", file="../analysis_and_temp_files/05_cluster_structures/itol_clusters.txt")
itol_data<-cluster_info_col %>% mutate(node2=node) %>%
select(node,node2,color)
write.table(itol_data,"../analysis_and_temp_files/05_cluster_structures/itol_clusters.txt",append=TRUE,sep=",",quote = F, row.names = F, col.names=F)
knitr::include_graphics("../results/cluster_tree/clusters.png")
dge <- ann %>% mutate(ProteinID=str_replace(TranscriptID,"XANPAGTX0501","FUN")) %>% filter(ProteinID %in% lddt$tip.label) %>%
mutate(symbol1 = case_when(DGE=="Upregulated in lichen" ~ 1, T ~ -1),
symbol2 = case_when(DGE=="Upregulated in culture" ~ 1,T ~ -1)) %>%
select(ProteinID,symbol1,symbol2)
#prepare the dataset
cat("DATASET_BINARY\nSEPARATOR COMMA\nDATASET_LABEL,Differentially Expressed\nCOLOR,#ff0000\nFIELD_LABELS,Upregulated in lichen,Upregulated in culture\nFIELD_SHAPES,4,5\nFIELD_COLORS,#F8766D,#00B6EB\nDATA\n", file="../analysis_and_temp_files/05_cluster_structures/itol_dge.txt")
write.table(dge,"../analysis_and_temp_files/05_cluster_structures/itol_dge.txt",append=TRUE,sep=",",quote = F, row.names = F, col.names=F)
knitr::include_graphics("../results/cluster_tree/clusters_dge.png")
cazy_cluster_list<-combined %>%
mutate(cazy_binary=ifelse(is.na(CAZyme_new),"noncazy","cazy")) %>%
group_by(ClusterID,cazy_binary) %>% summarize(n=n()) %>%
pivot_wider(names_from = cazy_binary,values_from = n,values_fill=0) %>%
mutate(cazy_perc=cazy/(cazy+noncazy)) %>% filter(cazy_perc>0.5)
## `summarise()` has grouped output by 'ClusterID'. You can override using the
## `.groups` argument.
cluster_info_col_cazy <- cluster_info_col %>%
filter(cluster_id %in% cazy_cluster_list$ClusterID) %>%
mutate(node2=node) %>% select(node,node2,color)
#add 'range' for CAZymes not in the clusters above
ind_cazy_list<-combined %>% filter(!is.na(CAZyme_new),
!(ClusterID %in% cazy_cluster_list$ClusterID),
ClusterID!="pTM below threshold") %>%
mutate(node=str_replace(ProteinID,"XANPAGTX0501","FUN"),node2=str_replace(ProteinID,"XANPAGTX0501","FUN")) %>% select(node,node2)
#define colors as shades of light grey
colfunc <- colorRampPalette(c("#d4d4d4", "#a8a8a8"))
ind_cazy_list$color<-colfunc(nrow(ind_cazy_list))
#prepare the dataset
cat("DATASET_RANGE\nSEPARATOR COMMA\nDATASET_LABEL,CAZymes\nRANGE_COVER,clade\nDATA\n", file="../analysis_and_temp_files/05_cluster_structures/itol_cazy.txt")
write.table(rbind(cluster_info_col_cazy,ind_cazy_list),"../analysis_and_temp_files/05_cluster_structures/itol_cazy.txt",append=TRUE,sep=",",quote = F, row.names = F, col.names=F)
knitr::include_graphics("../results/cluster_tree/cazy_dge.png")
protease_cluster_list<-combined %>%
mutate(protease_binary=ifelse(is.na(Protease_new),"nonprotease","protease")) %>%
group_by(ClusterID,protease_binary) %>% summarize(n=n()) %>%
pivot_wider(names_from = protease_binary,values_from = n,values_fill=0) %>%
mutate(protease_perc=protease/(protease+nonprotease)) %>% filter(protease_perc>0.5)
## `summarise()` has grouped output by 'ClusterID'. You can override using the
## `.groups` argument.
cluster_info_col_protease <- cluster_info_col %>%
filter(cluster_id %in% c(protease_cluster_list$ClusterID,"cl32","cl83")) %>%
mutate(node2=node) %>% select(node,node2,color)
#add 'range' for proteases not in the clusters above
ind_protease_list<-combined %>% filter(!(ClusterID %in% c(protease_cluster_list$ClusterID,"cl32","cl83")),ClusterID!="pTM below threshold") %>%
filter(!is.na(Protease_new) | grepl("eptidase",InterPro) |
grepl("rotease",InterPro)) %>%
mutate(node=str_replace(ProteinID,"XANPAGTX0501","FUN"),node2=str_replace(ProteinID,"XANPAGTX0501","FUN")) %>% select(node,node2)
#define colors as shades of light grey
colfunc <- colorRampPalette(c("#d4d4d4", "#a8a8a8"))
ind_protease_list$color<-colfunc(nrow(ind_protease_list))
#prepare the dataset
cat("DATASET_RANGE\nSEPARATOR COMMA\nDATASET_LABEL,Protease\nRANGE_COVER,clade\nDATA\n", file="../analysis_and_temp_files/05_cluster_structures/itol_protease.txt")
write.table(rbind(cluster_info_col_protease,ind_protease_list),"../analysis_and_temp_files/05_cluster_structures/itol_protease.txt",append=TRUE,sep=",",quote = F, row.names = F, col.names=F)
knitr::include_graphics("../results/cluster_tree/protease_dge.png")
int_cluster_list <- c("cl04","cl16","cl18","cl19","cl20","cl21","cl22","cl23",
"cl24","cl24a","cl37","cl38","cl40","cl41","cl42","cl80",
"cl29","cl34")
cluster_info_col_int <- cluster_info_col %>%
filter(cluster_id %in% int_cluster_list) %>%
mutate(node2=node) %>% select(node,node2,color)
#prepare the dataset
cat("DATASET_RANGE\nSEPARATOR COMMA\nDATASET_LABEL,Putative Effectors\nRANGE_COVER,clade\nDATA\n", file="../analysis_and_temp_files/05_cluster_structures/itol_interest.txt")
write.table(rbind(cluster_info_col_int),"../analysis_and_temp_files/05_cluster_structures/itol_interest.txt",append=TRUE,sep=",",quote = F, row.names = F, col.names=F)
knitr::include_graphics("../results/cluster_tree/interest_dge.png")
effp<-read.delim2("../analysis_and_temp_files/01_predicting_effectors/effectorp_GTX0501.out")
effp$prot<-gsub( " .*$", "", effp$X..Identifier)
effp$prot<-str_replace(effp$prot,"FUN","XANPAGTX0501")
deep1<-read.csv2("../analysis_and_temp_files/01_predicting_effectors/deepredeef_prediction_1.csv",sep=",")
deep2<-read.csv2("../analysis_and_temp_files/01_predicting_effectors/deepredeef_prediction_2.csv",sep=",")
deep<-rbind(deep1,deep2)
deep$prot<-gsub( " .*$", "", deep$name)
deep$prot<-str_replace(deep$prot,"FUN","XANPAGTX0501")
effp %>% filter(prot %in% clusters_df$TranscriptID[clusters_df$cluster_id=="cl04"]) %>% select(prot,Prediction,Non.effector)
## prot Prediction Non.effector
## 1 XANPAGTX0501_000516-T1 Non-effector Y (0.79)
## 2 XANPAGTX0501_002012-T1 Non-effector Y (0.921)
## 3 XANPAGTX0501_002315-T2 Non-effector Y (0.96)
## 4 XANPAGTX0501_003678-T1 Non-effector Y (0.736)
## 5 XANPAGTX0501_005039-T1 Non-effector Y (0.853)
## 6 XANPAGTX0501_005768-T1 Non-effector Y (0.819)
## 7 XANPAGTX0501_009148-T1 Non-effector Y (0.962)
## 8 XANPAGTX0501_010247-T1 Non-effector Y (0.933)
deep %>% filter(prot %in% clusters_df$TranscriptID[clusters_df$cluster_id=="cl04"]) %>% select(prot,prediction,s_score)
## prot prediction s_score
## 533 XANPAGTX0501_000516-T1 effector 0.970979988574982
## 2088 XANPAGTX0501_002012-T1 non-effector 0.341907918453217
## 2401 XANPAGTX0501_002315-T2 effector 0.587720155715942
## 3831 XANPAGTX0501_003678-T1 effector 0.964024305343628
## 25210 XANPAGTX0501_005039-T1 effector 0.841638267040253
## 9971 XANPAGTX0501_005768-T1 effector 0.958712518215179
## 44871 XANPAGTX0501_009148-T1 non-effector 0.424879431724548
## 5617 XANPAGTX0501_010247-T1 non-effector 0.0446633771061897
hyd_cluster_list<-c(protease_cluster_list$ClusterID,cazy_cluster_list$ClusterID,
"cl05","cl07","cl11","cl12","cl58","cl32","cl83")
cluster_info_col_hyd <- cluster_info_col %>%
filter(cluster_id %in% hyd_cluster_list) %>%
mutate(node2=node) %>% select(node,node2,color)
#prepare the dataset
cat("DATASET_RANGE\nSEPARATOR COMMA\nDATASET_LABEL,Hydrolase\nRANGE_COVER,clade\nDATA\n", file="../analysis_and_temp_files/05_cluster_structures/itol_hydrolase.txt")
write.table(cluster_info_col_hyd,"../analysis_and_temp_files/05_cluster_structures/itol_hydrolase.txt",append=TRUE,sep=",",quote = F, row.names = F, col.names=F)
hyd_cluster_list<-c(protease_cluster_list$ClusterID,cazy_cluster_list$ClusterID,
"cl05","cl07","cl11","cl12","cl58","cl32","cl83")
cluster_info_col_hyd <- cluster_info_col %>%
filter(cluster_id %in% hyd_cluster_list) %>%
mutate(node2=node) %>% select(node,node2,color)
#prepare the dataset
cat("DATASET_RANGE\nSEPARATOR COMMA\nDATASET_LABEL,Hydrolase\nRANGE_COVER,clade\nDATA\n", file="../analysis_and_temp_files/05_cluster_structures/itol_hydrolase.txt")
write.table(cluster_info_col_hyd,"../analysis_and_temp_files/05_cluster_structures/itol_hydrolase.txt",append=TRUE,sep=",",quote = F, row.names = F, col.names=F)